Bioprocess Online for bioanalytics, biopurification, bioproduction

Navigating Tariffs: Implications And Strategies For Pharmaceuticals Manufacturers

The U.S. tariffs on trading partners bring a whole new set of challenges, but there are tactics and strategies companies can deploy to help offset the cost and operational impacts.

EDITOR'S DESK

2025 Cell Therapy Outlook From BPI West
Bioprocess Online and Cell & Gene spoke with Takeda’s Amy Shaw at BPI West to discuss the industry and her key takeaways from the conference.

Using AI And ML To Gain Insight Into Optimal Glycoforms

Bioprocess Online asked Nathan Lewis, Ph.D., to briefly explain the research he presented at BPI West 2025.

Impressions And Takeaways From BPI West 2025

Editor Tyler Menichiello reviews the most compelling topics and sessions from this year's BioProcess International U.S. West.

Areas For Advancement In Peptide Manufacturing

Experts from Eli Lilly, NervGen, and Piramal Pharma Solutions discuss the myriad of ways peptide manufacturing can be improved, drawing on years of industry experience and insight.

For Gilead, Sustainability Is More Than A PR Effort

Gilead's chief sustainability officer and SVP of operations, Joydeep Ganguly, explains the company's cultural focus on sustainability and how it influences everything from R&D to manufacturing.

GUEST COLUMNISTS

Climbing The Blockchain Ladder To Optimize Clinical Supply Forecasting
Layering AI on top of blockchain technology offers a powerful way to predict kinks in the supply chain. Here's a look at where the technology is headed.
How CAR-NKs Offer Powerful Therapeutic Flexibility
Induced pluripotent stem cells have emerged as a promising platform for producing CAR-engineered NK cells in a standardized, renewable, and scalable way.
Ramping Up GMP-Compliant CAR-NK Manufacturing At Scale With iPSCs
The ability to produce billions of NK cells in a single production run represents a transformative shift in the economics and logistics of cell therapy.
Pharmaceutical Sovereignty: The Resilience We Cannot Outsource
Pharmaceutical sovereignty is no longer a theoretical concern. Sovereignty in this context does not imply isolation, but rather strategic resilience: building robust national and regional capabilities that ensure security while enabling global collaboration.
Getting To The Heart Of CDMO Tech Transfer Excellence
Discover five key factors that drive a seamless and efficient technology transfer, highlighting how a culture of technical expertise, customer focus, and operational flexibility is crucial to success in the CDMO industry.
How AI Is A Game-Changer For Auditing Compliance And Efficiency
In the life sciences, audits have long been bogged down by repetitive tasks. AI is changing the way auditors operate, making compliance more seamless than ever.
March 2025 — CDMO Opportunities And Threats Report
Each month, Outsourced Pharma works in conjunction with PharmSource, part of GlobalData, to present its “Contract Manufacturing: Opportunities and Threats (CMOT) Report” to our readers. The report identifies CDMOs that might be impacted by key events affecting their clients, including company acquisitions, product acquisitions and licenses, product approvals, late clinical product terminations, and FDA rejections.
A Closer Look At Buffer Recycling For More Sustainable Bioprocessing
Recognizing the unexplored potential to save resources, one researcher realized consumption reduction of up to 50% during a key phase of downstream processing.

BIOPROCESSING WHITE PAPERS

Enhancing Safety And Efficacy Of mRNA-Based Therapeutics
Discover how Codex® HiCap RNA Polymerase optimizes mRNA yield while reducing dsRNA byproducts for safer, more effective therapeutics.

Optimized Fill And Finish To Limit DMSO's Negative Impact On T Cells
5/17/2023

In order to improve the existing cryopreservation paradigm, operators must consider fill/finish and cryopreservation techniques that streamline processing steps and minimize cells’ exposure to DMSO.
Upscaling hMSC Production Enhances Extracellular Vesicle Secretion And Cargo Profile
12/19/2024

Explore how the dynamic microenvironment of bioreactors influences the production and composition of extracellular vesicles (EVs), including exosomes, secreted by human mesenchymal stromal cells (hMSCs).
A Checklist For Efficient And Reliable Gene Therapy Manufacturing
6/3/2024

Gain insight into how to design and execute an efficient upstream AAV production process, and follow the checklist within to ensure all appropriate factors are considered at each phase of drug development.
Purity Analysis Methods For Synthetic Prime Editing Guide RNAs
9/8/2023

Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.
Finding An Optimal Harvest Solution By Considering Both Cost And Sustainability
3/27/2025

Optimize your bioprocessing harvest with single-use centrifugation. Reduce costs, waste, and space needs compared to traditional depth filtration methods.

More Bioprocessing White Papers

BIOPROCESSING APP NOTES & CASE STUDIES

More Bioprocessing App Notes & Case Studies

BIOPROCESS ONLINE CONTENT COLLECTIONS

This collection of articles digs into the industry’s growing focus on knowledge management as an indispensable facet of biomanufacturing and pharmaceutical development, exploring how it plays into risk management, quality, vendor relationships, and supply chain resilience.