Bioprocessing Application Notes & Case Studies

1. Stability Screening For Colloidal Stability: Diffusion Interaction Parameter Thermal Shift Assay 4/28/2025

   Colloidal stability is one of the most important properties to control due to the propensity for biopharmaceuticals to aggregate and the subsequent potential to severely affect the drug's efficacy and patient safety.

2. Why Cell Line Screening Is Crucial For Successful CDC Assay Development 4/28/2025
3. Demonstration Of Scalability For A Novel Fixed Bed Reactor Platform 4/28/2025

   Designed to enable efficient scalability, a new FBR platform allows operators to use one technology, with a standardized workflow, for their process development, scale-up, and manufacturing processes.

4. Characterizing Binding Interactions By ITC 4/24/2025

   Isothermal Titration Calorimetry is a powerful technique for analyzing biochemical binding events, which is crucial for understanding molecular interactions and enzyme kinetics in biomedical research.

5. A Novel Patient-Derived Colorectal Cancer Organoid Platform 4/22/2025

   Patient-derived organoids are revolutionizing drug discovery by mimicking tumors and predicting therapeutic efficacy. Discover a scalable bioprocess that enhances reproducibility and cost-effectiveness to pave the way for broader adoption.

6. IVT mRNA Encapsulation Efficiency Assessment 4/21/2025

   In vitro transcribed mRNA revolutionizes biotherapeutics, which necessitates thorough quality assessments. Discover how an analyzer system enhances encapsulation efficiency and critical quality attributes in IVT mRNA workflows.

7. CQA Assessment Of LNP-Encapsulated IVT mRNA 4/21/2025

   Learn more about issued guidelines on Critical Quality Attributes for IVT mRNA vaccines and biotherapeutics to focus on drug substance and LNP-encapsulated drug product assessment using an analyzer system.

8. Boost Your Lab's Performance: 3 Ways To Increase Efficiency 4/16/2025

   Maximize your research potential by overcoming workflow bottlenecks. This piece explores flexible strategies for increasing throughput and integrating automation seamlessly into your laboratory operations.

9. ThioBridge™ Conjugates 4/14/2025

   Discover how Abzena’s ThioBridge™ technology is enabling the next generation of stable, scalable, and clinically advanced ADCs through site-specific conjugation.

10. Transfer Of Fed-Batch To Semi-Perfusion Process 4/14/2025

    Continuous processes enhance product quality, yield, and cost savings. Explore transitioning a fed-batch process to perfusion using a small batch bioreactor system to optimize cell culture conditions and comparing performances.