Bioprocessing Application Notes & Case Studies

  1. Single-Step Influenza And Dengue Virus Purification With Mixed-Mode CHT Ceramic Hydroxyapatite XT Media
    9/21/2018

    As a media for simple, fast, scalable, and reproducible viral purification, CHT XT Media meets the demand for a robust media with excellent life time and single-step purification functionality for healthy process economics.

     

  2. S.U.B. Enhancements For High-Density Perfusion Cultures
    9/20/2018

    This study presents how strategic enhancements to the sparge and agitation systems of Thermo Scientific™ HyPerforma™ S.U.B.s have revealed the potential for a three- to four-fold improvement in mixing and mass transfer performance compared to legacy S.U.B. designs.

  3. Mass Transfer Of Single-Use Fermenters To Stirred Glass Bioreactors
    9/20/2018

    The HyPerforma S.U.F. performs similarly to stainless steel SIP/CIP fermentors, making it the best option against other single-use reactors that fall below the mark.

  4. Scale-up And Tech Transfer From 100 L SIP/CIP Vessel To The 300 L S.U.F.
    9/20/2018

    A collaborative study with a new customer with the objective of taking an existing, smaller preclinical E. coli process previously performed in stainless steel vessels and scaling it up quickly using the Thermo Scientific™ HyPerforma™ 300 L Single-Use Fermentor (S.U.F.)

  5. Total Transportation Management Saves Company $10.2 Million
    9/20/2018

    A leading multinational pharmaceutical company approached Fisher Clinical Services with an extensive clinical trial pipeline and the need to achieve a comprehensive, fully-managed transportation strategy. Learn more about our outsourced transportation option that delivered tangible results.

  6. Innovative, Flexible, And Time-Sensitive Packaging Solutions
    9/19/2018

    Given the rapidly changing landscape of today's trials, if sponsors wish to succeed, they must remain vigilant - attending to every detail of the process. Learn more about how several sponsors achieved success through these case-study examples.

  7. Buffer Filter Selection Guidelines
    9/17/2018

    In biotech drug manufacture, a significant proportion of filtration costs are attributable to filters utilized for removing fine contaminants and low levels of bioburden from buffers and wash fluids

  8. Chromassette®: Equivalent Performance Of Individual And Stacked Cassettes
    9/13/2018

    The stacking ability of matched Chromassette devices enables easy and quick adjustment of resin volumes in order to meet the capacity requirements of individual processes.

  9. Chromassette®: Examples Of Recently Tested Resins Suggest Wide Applicability Of The Technology
    9/13/2018

    This application note details bed integrity testing of some resins recently packed in Chromassette devices prior to shipment to end users.

  10. Evaluation Of Chromassette® Packed With Cation Exchange Resin
    9/13/2018

    A modular chromatography technology that readily meets today’s bio-separation scale up demands for improved ease of use.