Bioprocessing Application Notes & Case Studies

1. Using Human-Centered Engineering To Improve HPLC Solvent Handling 10/15/2026

   Real-world HPLC workflows show how closed-system solvent handling can address contamination, downtime, and waste across laboratory settings.

2. Supply Chain Diversification In Biopharmaceutical Manufacturing 10/15/2026

   Single-source dependencies in biologics manufacturing carry risks that surface as programs scale toward commercial production. 

3. Improving Formulation And Aliquoting Efficiency With Mixing Solutions 10/14/2026

   Separate formulation, filtration and aliquoting add transfers and integrity tests. A single closed flowpath can improve time, yield and contamination control.

4. High-Yield Cell Therapy Bioproduction 10/14/2026

   Producing billions of dental pulp stem cells strains static culture and complicates harvest. A closed planar perfusion approach offers another route, with scale-up lessons from one developer.

5. Improving Stability Through Science-Led OSD Reformulation 10/13/2026

   A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

6. De-Risking Complex Generic OSD Development 10/13/2026

   Complex generic tablet development requires early alignment of regulatory strategy, QbD formulation, discriminatory dissolution, and reference-scaled bioequivalence.

7. Cell Culture Monitoring With An Innovative Analyzer 10/9/2026

   Evaluate the speed, precision, and consistency of automated bioanalyte testing, including sensor detection principles, quality controls, glucose, and lactate linearity.

8. Method Evaluation Guidance For Transferring A Process 10/9/2026

   Moving a cell counting method between analyzers in a lab requires evidence of comparability. A structured study of suspension and adherent models tests precision and linearity against defined criteria.

9. An Automated Cell-Processing Platform For MSC Harvest 10/7/2026

   Discover closed, automated harvest, formulation, and dispensing of umbilical cord MSCs at commercial scale, with data on viability, recovery, and filling precision, including single runs.

10. Purification Of Antibodies With Nuvia™ wPrime 2A Media, A Scalable Hydrophobic Weak Anion Exchange Resin 10/5/2026

    Discover how mixed-mode AEX-HIC resin in flow-through mode optimizes downstream mAb purification, lowering aggregate levels to 0.7% with high monomer recovery.