Bioprocessing Application Notes & Case Studies

1. Aligning Scientific Expertise To Accelerate Complex Biologics Programs 7/17/2026

   Complex biologics often outgrow traditional development platforms. Learn how an integrated development strategy can accelerate timelines while reducing risk.

2. CLD Case Study: Complex Biologics – Bispecific Fusion Nanobody 7/17/2026

   See how a bispecific fusion nanobody (BFN) achieved BsAb titers above 7 g/L with 5 of 6 clones stable beyond 60 generations — from CLD through cGMP manufacturing.

3. Unlocking Robust Separations For Modern Peptide Therapeutics 7/14/2026

   As peptide therapeutics grow more complex, impurity profiling demands greater chromatographic confidence. See how robust reproducibility can support reliable GLP-1 receptor agonist analysis.

4. Using dSEC-7 Column For Separation And Length Determination Of mRNA 7/13/2026

   mRNA analysis depends on methods that can separate broad size ranges. Learn how retention time can help estimate transcript length and complement capillary electrophoresis workflows.

5. What Is Size Exclusion Chromatography (SEC)? 7/13/2026

   Aggregation can compromise mAb quality at many stages of development. Learn why size exclusion chromatography is a trusted approach for detecting aggregates and supporting confident characterization.

6. Peptide Mapping Of Adeno Associated Virus Capsid Proteins 7/13/2026

   Peptide mapping helps reveal AAV capsid protein identity, sequence coverage, and potential modification patterns, giving gene therapy teams a clearer view of viral protein quality across workflows.

7. Native RPLC For ADCs: How Column Hydrophobicity Shapes DAR Separation 7/13/2026

   ADC characterization does not have to be overwhelmed by complex intact MS profiles. Smart column selection can improve separation, clarify critical quality attributes, and make ADC analysis easier.

8. Sample Clean-Up After N-Linked Glycan Release And Labeling 7/13/2026

   Glycan profiling starts with effective clean-up. See how comparable recovery across key labeled glycans and sialylated glycan groups can support confident analysis while helping labs manage costs.

9. Production Of Disulfide-Rich Cow Knob Domain Antibodies 7/8/2026

   Discover how a microbial expression platform enabled high-titer production of disulfide-rich bovine knob domain antibodies with confirmed SARS-CoV-2 spike protein binding activity at 19 nM IC50.

10. A Sterilizing-Grade Membrane For Efficient Filtration Of Biologics 7/7/2026

    Higher flow rates and a smaller process footprint can create meaningful gains across sterile filtration steps. Explore the performance data and where efficiency improvements may be possible.