Bioprocessing Application Notes & Case Studies

1. Improved T Cell Expansion Using Closed, Automated Stirred-Tank Bioreactors 6/10/2025

   A shift from traditional rocking motion systems to stirred-tank bioreactors can enhance T cell expansion, offering greater scalability and more intimate process control.

2. Comparing Serum-free To Serum-Supplemented Media 6/9/2025

   Reducing serum in vaccine manufacturing is a key consideration for lowering costs and improving supply security. We compare performance in serum-free versus serum-supplemented media.

3. A Temperature-Stable Replacement For Animal Trypsin In Cell Dissociation Applications 6/9/2025

   Improve cell dissociation with a gentle, recombinant enzyme. This temperature-stable protease shows dissociation kinetics similar to porcine trypsin but with lower cell toxicity and greater overall purity.

4. Understanding EndoCleave's Role In Viral Vector Manufacturing 6/4/2025

   Achieving high-quality viral vectors demands rigorous control over contaminants. Learn about enzymatic approaches to significantly reduce nucleic acid impurities in your manufacturing processes.

5. Evaluating The Impact Of Flexible Environmental Controls On HEK293 Cell Growth And Viability 6/2/2025

   Achieving high viable cell densities in HEK293 cultures is crucial. This study examines how precise environmental adjustments support robust growth for gene therapy applications.

6. Evaluating Contamination Control For Open-Vessel Cultivation 5/30/2025

   Open-vessel cultivation can be challenging due to airborne contaminants. Learn how continuous air filtration within an incubator shaker ensures a particle-free environment.

7. Benchmarking Filtration Performance Of TFF Cassettes 5/30/2025

   Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.

8. Taking A Look At AAV Production Using HEK293 In A Perfusion Process 5/28/2025

   Discover a scalable, cost-effective solution for gene therapy manufacturing with VintaProcess™ — featuring VintaCell™, VintaFect™, and fixed-bed bioreactor technology.

9. The Evolution Of AAV Production: Scaling Through Nature Instead Of Brute Force 5/28/2025

   This study evaluates the performance and productivity of VintaProcess in addressing the persistent manufacturing challenges in AAV gene therapy production.

10. IR Spectral Signatures Of GC, AU, And GU Base Pairing In H2O-Based Buffer By MMS 5/22/2025

    Explore a label-free approach to characterize RNA structure with high sensitivity. See how specific base pair types are resolved, providing a clearer picture of RNA folding.