The Allegro STR bioreactor family combines Pall’s bioprocess engineering expertise, cell culture know-how and our drive for quality into a series of single-use bioreactors that deliver consistent and scalable cell culture performance across the range. The Allegro STR bioreactor family has a direct bottom-driven impellor allowing power inputs up to 0.25 W/kg, resulting in high oxygen transfer rates and short mixing times.
By Brandy Sargent, Editor In Chief, The Cell Culture Dish
This article was originally published on the Downstream Column, May 17, 2017 and is reprinted here with permission - https://downstreamcolumn.com/cool-tools/pre-activated-resins-ligand-immobilization-facilitate-creation-customized-affinity-purification-media/
In the development of biopharmaceuticals there are times when an off the shelf affinity chromatography medium is unavailable or isn't highly selective for the target molecule being purified. It is possible then to design a custom chromatography solution by coupling a specific ligand to a pre-activated resin.
Leading Analytical Scientists with Advanced Instrumentation.
The RRN 3xx5 series (without ultrasonic bath) is the perfect solution for the high output range Each cleaning station is completely free of hoses. This not only increases pharmaceutical safety, but also simplifies maintenance and cleaning efforts. By using a servo driven internal spraying needle motion, different container sizes can be processed without changing the internal spraying needles. The external cleaning stations are mounted above the transport system and can be easily adjusted for a specific height, angle, and lateral position.
PODs can be utilized in a multitude of applications including: monoclonal antibodies, vaccine or recombinant proteins, personalized medicines, cell and gene therapy and even laboratory use. The utilization of single-use processing equipment within the POD creates the most flexible production platform available.
Considering that 90% of drug candidates have bioavailability issues, making sure your program is prepared for all phases of clinical trials from the very start is the fast way forward. Patheon Solubility Enhancement Services approaches BCS II and IV drug substance solubility issues a fundamentally different way that identifies the solubility enhancement technologies most likely to work before you get started. That helps eliminate rework and worry later on.
Emergent’s two 240 ft2 lyophilizers can hold lot sizes of:
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