Purification Sourcing Center

Biologic purification is a critical series of downstream steps required to capture a target biomolecule and remove host cell related impurities, process related impurities, and product related impurities.

Those steps include protein extraction or isolation, purification, and polishing. The purification process generally exploits differences in protein size, biological activity, physicochemical properties, and binding affinity to produce specific, pure proteins. Whether at bench-scale or in a high-volume commercial production environment, the purification of biologic pharmaceutical products is complex and expensive, typically representing upwards of 50 percent of a therapeutic antibody’s downstream manufacturing cost, and often causing production bottlenecks. BioProcess Online offers a host of timely resources to help you manage the cost—and overcome the complexity—of the downstream purification process.

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Purification Provider - Bio-Rad Laboratories
Bio-Rad Laboratories

Bio-Rad Laboratories is a leading provider of innovative tools to the life science and clinical diagnostics markets, where the company’s products are used for scientific discovery, drug development, and biopharmaceutical production.

Capabilities

Purification Provider - Cytiva
Cytiva

Cytiva provides the expertise and tools spanning a wide range of applications from basic research of proteins and cells to large-scale purification of biopharmaceuticals. Within the bioprocessing space, Cytiva provides products and expertise for developers and manufacturers of biotherapeutics.

Capabilities

Purification Provider - JSR Life Sciences
JSR Life Sciences

JSR Life Sciences is a global built on more than 50 years of polymer expertise and began research in the life sciences more than 30 years ago. Using a variety of integrated, leading-edge technologies, JSR Life Sciences provides materials that contribute to the manufacturing process of biopharmaceuticals, life science research applications, in vitro diagnostics and medical devices.

Capabilities


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Purification Provider - MilliporeSigma Process Solutions
MilliporeSigma Process Solutions

At MilliporeSigma, our mission is to help our customers improve human health and life worldwide. This commitment means providing leading life science products and services in ways that also help improve the communities and environment in which we all live.

Capabilities

Purification Provider - Sartorius Stedim Biotech
Sartorius Stedim Biotech

Sartorius is a leading international pharmaceutical and laboratory equipment supplier. With our innovative products and services, we are helping our customers across the entire globe to implement their complex and quality-critical biomanufacturing and laboratory processes reliably and economically.

Capabilities

Purification Provider - Thermo Fisher Scientific
Thermo Fisher Scientific

To meet the increasing demand for biologics worldwide, you need to expect more from suppliers. It isn’t just about the products we deliver, but how we do business together. With a collaborative approach that is grounded in our technical knowledge, we work with you to achieve optimal bioprocessing outcomes.