Purification Provider Sourcing Center

Purification Sourcing Center

Biologic purification is a critical series of downstream steps required to capture a target biomolecule and remove host cell related impurities, process related impurities, and product related impurities.

Those steps include protein extraction or isolation, purification, and polishing. The purification process generally exploits differences in protein size, biological activity, physicochemical properties, and binding affinity to produce specific, pure proteins. Whether at bench-scale or in a high-volume commercial production environment, the purification of biologic pharmaceutical products is complex and expensive, typically representing upwards of 50 percent of a therapeutic antibody’s downstream manufacturing cost, and often causing production bottlenecks. BioProcess Online offers a host of timely resources to help you manage the cost—and overcome the complexity—of the downstream purification process.

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Purification - 3M Biopharmaceutical Purification
3M Biopharmaceutical Purification

3M biopharmaceutical purification solutions work to optimize your processes, applying our biopharma experience, material science and proprietary technologies to help you develop highly effective purification solutions. Our solutions are designed for upstream and downstream processing. These solutions are focused on 3M innovative technologies for the development and manufacturing of recombinant proteins including mAbs, vaccines, and therapeutic plasma proteins.

Capabilities

Purification - Asahi Kasei Bioprocess America, Inc.
Asahi Kasei Bioprocess America, Inc.

Asahi Kasei Bioprocess America, Inc. is dedicated to providing solutions to ensure safety, efficiency and purity for your therapeutic products within the bioprocess and pharmaceutical industries. We engineer fluid management equipment for Inline Buffer Formulation, Oligonucleotide Synthesis, Chromatography, Virus Filtration and more.

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Purification - Astrea Bioseparations
Astrea Bioseparations

Astrea Bioseparations is a supplier delivering scalable, reliable solutions, with resins used in more than 20 FDA or EMA approved manufacturing processes. At Astrea Bioseparations we create tailored solutions that streamline bioprocesses from research through commercial phases. Our product portfolio includes standard and custom adsorbents and columns, complemented by our support services, that help customers run successful affinity chromatography and bioseparations projects.

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Purification Provider - Bio-Rad Laboratories
Bio-Rad Laboratories

Bio-Rad Laboratories is a leading provider of innovative tools to the life science and clinical diagnostics markets, where the company’s products are used for scientific discovery, drug development, and biopharmaceutical production.

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Purification Provider - bio-techne
bio-techne

Bio-Techne empowers researchers in Life Science and Clinical Diagnostics by providing high-quality reagents instruments, custom manufacturing, and testing services. Whether you are at the cutting edge of academic research, translating basic discoveries to therapeutic leads, or at a facility that requires the highest level of diagnostic testing, our innovative products and services provide the solutions you need to achieve success.

Capabilities

Purification Provider - Custom Sensors & Technology
CAI

CAI exists to help our customers design, deliver, operate, and maintain quality-critical manufacturing (GMP related) or mission-critical facilities. Our engineering, technical, and consulting services encompass all aspects of operation: equipment, automation, process, and human performance. The result is a superior level of operational performance and reliability.

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Purification Provider - Cygnus Technologies
Cygnus Technologies

Cygnus helps companies developing therapeutic proteins, vaccines, antibodies, plasma derivatives and gene therapies to ensure the safety of biotherapeutics prior to human trials, regulatory approval and commercial release. Cygnus provides analytical tools and solutions delivering insights to improve bioprocess development for faster regulatory approval and better clinical outcomes.

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Purification Provider - Cytiva
Cytiva

Cytiva provides the expertise and tools spanning a wide range of applications from basic research of proteins and cells to large-scale purification of biopharmaceuticals. Within the bioprocessing space, Cytiva provides products and expertise for developers and manufacturers of biotherapeutics.

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Purification Provider - JSR Life Sciences
JSR Life Sciences

JSR Life Sciences is a global built on more than 50 years of polymer expertise and began research in the life sciences more than 30 years ago. Using a variety of integrated, leading-edge technologies, JSR Life Sciences provides materials that contribute to the manufacturing process of biopharmaceuticals, life science research applications, in vitro diagnostics and medical devices.

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Purification Provider - JSR Life Sciences
Minebea

Minebea Intec is a premium provider of industrial weighing and control equipment. Our product solutions are used throughout the entire manufacturing process ranging from incoming goods inspection to production, to final quality control and logistics. We manufacture high-quality measurement equipment, such as high-capacity load cells and industrial scales. Our company ranks amongst the world's leading suppliers in the sector of process tank and hopper weighing.

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Purification Provider - MilliporeSigma Process Solutions
MilliporeSigma

At MilliporeSigma, our mission is to help our customers improve human health and life worldwide. This commitment means providing leading life science products and services in ways that also help improve the communities and environment in which we all live.

Capabilities

Purification Provider - Pall
Pall Corporation

Pall's leading-edge filtration, single-use systems, separation, purification and analytical technologies, as well as technical services in validation, assays and process optimization applicable to laboratory and pilot-scale development, play an essential role in the industry's ability to manufacture these products. As an established global provider of analytical and purification technologies, Pall supports faster development of new drugs and vaccines around the world.

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Purification Provider - Sartorius Stedim Biotech
Sartorius

The Sartorius Group is a leading international partner of life science research and the biopharmaceutical industry. The Bioprocess Solutions Division with its broad product portfolio focusing on single-use solutions helps customers to manufacture biotech medications and vaccines safely and efficiently. The Group has been annually growing by double digits on average and has been regularly expanding its portfolio by acquisitions complementary technologies.

Capabilities

Purification Provider - SCIEX
SCIEX

At SCIEX, our mission is to deliver solutions for the precision detection and quantification of molecules, empowering our customers to protect and advance the wellness and safety of all.

SCIEX has led the field of mass spectrometry for 50 years. From the moment we launched the first ever commercially successful triple quad in 1981, we have developed groundbreaking technologies and solutions that influence life-changing research and outcomes.

Purification Provider - Thermo Fisher Scientific
Thermo Fisher Scientific

To meet the increasing demand for biologics worldwide, you need to expect more from suppliers. It isn’t just about the products we deliver, but how we do business together. With a collaborative approach that is grounded in our technical knowledge, we work with you to achieve optimal bioprocessing outcomes.


Purification Provider - W.L. Gore & Associates
W.L. Gore & Associates

GORE Protein Capture Devices with Protein A utilize a unique membrane solution that provides a binding capacity advantage at high flow rates and improves the speed of purification versus traditional technologies. The GORE Protein Capture Device scales across sizes without compromising binding capacity or speed and is available is sizes for early drug discovery screening, late stage optimization, process development, and GMP clinical applications.

Capabilities

Purification Provider - Waters Corporation
Waters Corporation

Waters Corporation unlocks the potential of science through analytical measurement technology, deep scientific expertise, and reliable insights to enhance human health and well-being. As a global leader in analytical instruments, consumables, and software, Waters has pioneered chromatography, mass spectrometry, and thermal analysis innovations serving the life, materials, and food sciences for more than 60 years.

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