Purification Sourcing Center
Biologic purification is a critical series of downstream steps required to capture a target biomolecule and remove host cell related impurities, process related impurities, and product related impurities.
Those steps include protein extraction or isolation, purification, and polishing. The purification process generally exploits differences in protein size, biological activity, physicochemical properties, and binding affinity to produce specific, pure proteins. Whether at bench-scale or in a high-volume commercial production environment, the purification of biologic pharmaceutical products is complex and expensive, typically representing upwards of 50 percent of a therapeutic antibody’s downstream manufacturing cost, and often causing production bottlenecks. BioProcess Online offers a host of timely resources to help you manage the cost—and overcome the complexity—of the downstream purification process.
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Looking for help with your Purification project? If you're searching for information or a supplier, let Life Science Connect lend you a hand.
Asahi Kasei Bioprocess America, Inc.
Asahi Kasei Bioprocess America, Inc. is dedicated to providing solutions to ensure safety, efficiency and purity for your therapeutic products within the bioprocess and pharmaceutical industries. We engineer fluid management equipment for Inline Buffer Formulation, Oligonucleotide Synthesis, Chromatography, Virus Filtration and more.
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Avantor
Your partner for customized solutions.
Avantor's flexible and responsive bioprocessing solutions help you quickly move biologics from research to reality. We collaborate at every step in scaling up your monoclonal antibodies (mAbs) production — maximizing productivity, mitigating risk and reducing waste to accelerate your process.
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Bio-Rad Laboratories
Bio-Rad Laboratories is a leading provider of innovative tools to the life science and clinical diagnostics markets, where the company’s products are used for scientific discovery, drug development, and biopharmaceutical production.
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Have questions about selecting the right Purification product?
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CARR Biosystems
With over three decades of pioneering versatile stainless steel and single-use separation systems, CARR Biosystems delivers high-performance, fully-scalable bioprocessing solutions to accelerate process development. We help scientists and engineers produce vital biologics in emerging and established markets, including cell and gene therapy, vaccine development, microbial fermentation, and cellular agriculture.
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Cygnus Technologies
Cygnus helps companies developing therapeutic proteins, vaccines, antibodies, plasma derivatives and gene therapies to ensure the safety of biotherapeutics prior to human trials, regulatory approval and commercial release. Cygnus provides analytical tools and solutions delivering insights to improve bioprocess development for faster regulatory approval and better clinical outcomes.
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Cytiva
With a rich heritage dating back hundreds of years, Cytiva brings a wealth of technical expertise and talent, a broad and deep portfolio, and exceptional service help researchers and biopharma advance therapeutics at every stage from discovery to delivery. We supply the tools and support our customers need to work better, faster, and safer, leading to the delivery of transformative medicines to patients.
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Danaher Life Sciences
Every day, scientists around the world are dedicated to unraveling the mysteries of disease, discovering novel therapies and vaccines, and conducting crucial drug testing. Danaher Life Sciences comprehensive capabilities go beyond research, enabling us to drive the development of innovative biopharmaceuticals, revolutionary cell and gene therapies, and other breakthrough treatments.
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Ecolab, Purolite Resins
Ecolab Purolite Resins™ is a leading manufacturer of ion exchange, catalyst, adsorbent and advanced polymers. The company has manufacturing facilities in the USA, China, and Romania, and operates dedicated R&D centers in the USA, China, Romania, Russia, and the UK. Ecolab, Purolite Resins is the only globally-acting company focused exclusively on resin technology and is dedicated to solving the most difficult process challenges.
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Federal Equipment Company
Federal Equipment Company is a reliable resource for pharmaceutical processing and packaging equipment needs, with over 60 years of expertise working with manufacturers seeking to buy and sell used equipment.
MilliporeSigma
At MilliporeSigma, our mission is to help our customers improve human health and life worldwide. This commitment means providing leading life science products and services in ways that also help improve the communities and environment in which we all live.
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NanoTemper Technologies, Inc.
Our mission at NanoTemper Technologies is to create biophysical tools for scientists in drug discovery and development who need to tackle challenging characterizations. We build instruments that enable researchers everywhere develop new and improved drug modalities – from small molecules to biologic therapeutics and AAVs – for a wide range of therapeutic areas.
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Sartorius
The Sartorius Group is a leading international partner of life science research and the biopharmaceutical industry. The Bioprocess Solutions Division with its broad product portfolio focusing on single-use solutions helps customers to manufacture biotech medications and vaccines safely and efficiently. The Group has been annually growing by double digits on average and has been regularly expanding its portfolio by acquisitions complementary technologies.
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Thermo Fisher Scientific
To meet the increasing demand for biologics worldwide, you need to expect more from suppliers. It isn’t just about the products we deliver, but how we do business together. With a collaborative approach that is grounded in our technical knowledge, we work with you to achieve optimal bioprocessing outcomes.
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W.L. Gore & Associates
GORE Protein Capture Devices with Protein A utilize a unique membrane solution that provides a binding capacity advantage at high flow rates and improves the speed of purification versus traditional technologies. The GORE Protein Capture Device scales across sizes without compromising binding capacity or speed and is available is sizes for early drug discovery screening, late stage optimization, process development, and GMP clinical applications.
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