Bioprocessing White Papers

1. Software Automation In The Blood And Biologics Industry 1/11/2022

   Explore the different categories of solutions available to improve process efficiencies as well as the needs and wants that they address.

2. Modernizing Biopharma Manufacturers To Improve Quality And Safety 1/10/2022

   Read how proven, scalable digital solutions to modernize pharmaceutical product innovation and development gives enterprises an edge in meeting the manufacturing guidelines for pharmaceuticals while elevating the entire industry.

3. A Guide To Eliminating Small-Bore Connector Failures 12/28/2021

   The ISO 80369 standard is meant to design out the misconnection failure mode of small-bore luer fittings used with liquids and gases. This white paper discusses practical steps you can take to adapt to the new ISO requirements and addresses the common concerns, challenges and proposed solutions when switching to the new connector geometry.

4. Rationale Behind Just-in-Time (JIT) Component Suppliers In Biopharma 12/22/2021

   Teaming up with an external partner that has expertise in just-in-time inventory management minimizes risk when moving away from batch inventory replenishing

5. Pharma Manufacturing’s Digital Journey 12/16/2021

   The implementation of technologies and practices that improve efficiency, speed, and adaptability gives enterprises an edge while elevating the entire pharmaceutical industry. In this paper we detail the approaches pharma companies are taking to ensure long-term relevance in the value chain.

6. In Vivo-like Cell Culture: The Impact Of 3-Dimensional Technologies On Your Cell-based Applications 12/14/2021

   The limitations of 2D cell culture can cause roadblocks to research and contribute to poor predictive power of preclinical cell-based drug and toxicity screening assays. In this article we explore several more reasons why 3D is better and provide tips for perfecting the technique for optimal results.

7. Modern Containment Solutions In OSD Processes 12/14/2021

   There’s a changing landscape in the containment world for OSD processing. We now have very short-range production planning and we see smaller batch sizes and more changeover, which require greater levels of efficacy, efficiency, and speed. In this paper we consider the pros and cons between a hard-wall system and a flexible-wall containment systems.

8. How To Intensify Your Blood Plasma IgG Purification 12/9/2021

   In this white paper, we present the results from our collaboration with Taipei Medical University to develop and evaluate the reliability and consistency of various new steps to purify plasma-derived IgG. The intensified workflow includes flow-through mode chromatography and single-pass tangential flow filtration to achieve high recovery of a high quality product.

9. Streamlining Upstream Plasmid DNA Manufacturing 12/9/2021

   Here we will discuss the scalable process workflow solutions available from initial R&D investment to clinical testing and commercialization.

10. Monitoring Mammalian Cell Cultures: Raman vs. MIR Spectroscopy 12/9/2021

    A direct comparison between the two technologies was conducted to investigate which system is more suitable for analyzing mammalian cell culture(s).