Bioprocess Online for bioanalytics, biopurification, bioproduction

fundamental comparison metaphor or analogy-GettyImages-2191773530

Comparing Advanced Modality Needs, Part 1: Manufacturing

ADCs, AOCs, ATMPs, cell and gene therapies, and oligonucleotide therapeutics represent distinct but interconnected approaches to precision medicine. Let's take a closer look at their manufacturing needs.

More Featured Editorial

EDITOR'S DESK

Contextualizing Data To Enable AI And Prevent Knowledge Leaks
Bioprocess Online's Tyler Menichiello interviews Martin Kockx, a principal manufacturing systems engineer at Vertex Pharmaceuticals, on his presentation at 2026 BPI, “Transforming Biomanufacturing: Why Architecture Must Precede Analytics."

On The Ground At BPI: Jacqualyn Schulman, Ph.D., On Accelerating Clonal CLD

An interview with Jacqualyn Schulman, Ph.D., a principal scientist at Bristol Myers Squibb (BMS), on her presentation at BPI 2026, “Fast-Tracking CHO Cell Line Development Using Integrated Engineering Strategies.”

AstraZeneca's Focus On Predictive Control, Semi-Autonomous Processing

This article captures key takeaways from a BioProcess International keynote by Preeya Boppana, director of MSAT process analytics and laboratories at AstraZeneca, titled “Transforming Biologics Manufacturing: Leveraging Predictive Analytics and Advanced Process Control for Next-Generation Operations.”

Prioritizing Quality Over Everything

Regulatory compliance and cGMP manufacturing expert Tatyana Matveeva, Ph.D., explains the role and importance of a quality unit in an organization, as well as what happens when it’s compromised.

Evaluating The Levers Driving Productivity In Bioprocessing

Experts discuss where productivity gains can be achieved and how development teams should seek to improve process performance in this recap of the Bioprocess Online Live event "The Levers And Tradeoffs That Drive Process Productivity."

GUEST COLUMNISTS

Closing The Gap Between Modeling And GMP Predictive Control
Predictive control offers opportunities to improve process consistency, reduce variability, and respond to changing manufacturing conditions before they cause deviations.
IT/OT Convergence Could Lighten Biopharma's Automation Burden
Integration lets frameworks talk to each other through middleware. Convergence brings them under the same architecture, which can can reduce costs and maintenance.
Beyond The Plate Count: How To Build A Defensible Environmental Monitoring Trend Review
Determining whether a drug manufacturing environment is stable, drifting, or developing a recurring loss-of-control signal requires integrated trend evaluation.
Want More Sustainable Biopharma Packaging? Try These Levers
Biopharmaceutical packaging optimization must not compromise the goods inside or compliance, so sustainable packaging developers might need to think outside the box.
What Europe's Draft Annex 22 Actually Asks Of Human Oversight Of AI
The European Commission and the Pharmaceutical Inspection Co-operation Scheme (PIC/S) consulted on draft Annex 22, Artificial Intelligence. Here's what you should know.
How To Keep Your 'Big Bang' Platform Switch From Becoming A Big Bust
Leaders at a Roche fill/finish facility describe the tactile steps involve to change EMS, ERP, and WMS all at once with no rollback option.
How Is Your Glass Supplier Adapting To Europe's Energy Crisis?
Europe's glass manufacturers, including those making pharmaceutical lab glassware, have experienced a series of energy shocks. Many have adopted sustainability practices.
Fine-Tuning Bioseparation Column Geometry With 3D-Printed Monoliths
If geometric control, not retention, is the priority in viral vector separation, research group says high-resolution 3D-printing chromatography monoliths can be useful.

BIOPROCESSING WHITE PAPERS

Digital Solutions Enhance Pharmaceutical Manufacturing Performance
Personalised therapies and advanced technologies are reshaping manufacturing. Explore how intelligent automation can improve flexibility, strengthen data integrity, and accelerate production.

A Journey To Boundless Automation In Life Sciences
7/1/2025

Boundless automation reimagines industrial computing through seamless integration of the intelligent field, edge, and cloud, unified by a real-time data fabric that enables digital transformation.
The Proven, Practical Gateway To Upstream Process Intensification
11/18/2025

N-1 perfusion enables higher inoculum densities, faster production, and reduced costs without altering fed-batch processes. Explore a practical path to intensification for biologics manufacturers.
Achieving Unmatched Accuracy And Compliance In Pressure Sensing
9/27/2026

Discover how advanced pressure sensing can improve measurement accuracy, simplify system design, and support more efficient, sustainable bioprocessing.
Cell Based Potency Assays: De-Risk Your Path With An Experienced CDMO
4/21/2026

Thorough characterization is key to unlocking the potential of antibody-based therapeutics. Leveraging a CDMO's extensive capabilities and expertise can allow you to navigate the biopharmaceutical development landscape.
Tablet Manufacturing Technologies For Solid Drug Formulation
4/2/2025

Compressed tablets are common oral solid dosages that contain the API and various excipients. Learn about the critical steps in selecting manufacturing methods and excipients to achieve the desired therapeutic effects and stability.

More Bioprocessing White Papers

BIOPROCESSING APP NOTES & CASE STUDIES

More Bioprocessing App Notes & Case Studies

NEW FOR OUR READERS

EDITORIAL COLLECTIONS KNOWLEDGE CENTER

Editorial Collections are subscriber-only, curated resources that combine expert interviews, feature articles, and industry analysis to help readers better understand emerging trends, operational challenges, regulatory developments, and best practices shaping the biopharma industry.

More Editorial Collections