FEATURED ARTICLES

• Address Current Challenges In Gene Therapy Viral Vector Manufacturing

  This article addresses key advancements at each step in the production of viral vectors — from maximizing titer output at scale upstream to optimized formulation compositions at fill/finish — to support commercial scale.

• Meeting Local Regulations With Ready-To-Use Buffer Solutions

  Learn about a ready-to-use, custom buffer solution provided to a biopharmaceutical manufacturing facility in order to help them reduce costs and the amount of time spent on QC testing and validation.

• High-Quality Serum to Improve Performance And Supply Stability

  A consultative partnership brought valuable solutions to a global CDMO that was experiencing performance issues with their fetal bovine serum, and needed a new product source of superior quality fast.

• Custom Formulation Solution Including An Animal-Origin Element

  Explore the customized, multi-component solution designed to meet quality and packaging specifications, while including an animal-origin element, as well as a non-compendial component.

• Custom Solutions For Efficient Buffer Management

  Learn about the services that helped four companies ramp up their mAb production despite complications when it comes to hydration and buffer prep.

• Enhance Virus Clearance Process Capability With Biodegradable Detergent

  Learn more about an effective, biodegradable solution for the viral inactivation process that controls protein impurities and is compatible with downstream unit operations.

• Outsourcing Manufacturing Of Acetic Acid And Benzyl Alcohol Solutions

  Custom buffer solutions produced for a multinational biopharmaceutical company, enabled a fast facility expansion while still meeting the customers strict quality and regulatory requirements.

• Overcoming Risk In Cell And Gene Production

  To meet the speed to market demands of today requires process standardization and portability, improvements in raw material supply and sourcing and greater supply chain control.

• Four Best Practices For Single-Use Supply Chain Success

  What are four of best practices for single-use supply chain management and how can you avoid the worst-case scenario of being dependent upon an unreliable or small supply chain?

• AI Improving Inventory Management For Single-Use Systems Manufacturing

  The use of AI and machine learning tools can begin the process of moving from predictive, human-driven inventory management and manufacturing processes to genuine, data-driven decision making

• Harnessing Amino Acid Derivatives To Improve Monoclonal Antibodies

  Recent research in the fast-growing market of monoclonal antibodies (mAbs) identifies excipients that reduce viscosity of high-concentration formulation and improve stability across a wide concentration range.

• Protein A Resin Screening For Mouse IgG

  A study was conducted to evaluate the resin performance for a leading medical technology company needed a better purification process solution.

• Performance Of Protein A Resins For Different mAbs

  Review a Protein A resin solution assisting biotech companies who are working with and removing impurities from a wide variety of antibodies.

• Solving Cost And Supply Challenges In Biopharma Downstream Processing

  In response to the growing demand for monoclonal antibodies, researchers are looking at different areas of the downstream process where they can improve efficiency and scalability.

• De-risks Your Monoclonal Antibody Scale-Up Process

  Improve your mAb production by adopting a technology platform approach using a fluid handling system that can transition from development to your final production volume.

• The Case For Early Use Of cGMP Raw Materials

  Using cGMP grade reagents earlier makes for a seamless transition while maintaining quality and viability.

• Downstream Process Intensification: Enhanced mAb Purification

  Learn more about an integrated monoclonal antibody (mAb) downstream purification process that enables significant throughput improvement while removing critical impurities.

• Improve Your Processes With Alternative Buffer Management Strategies

  Understanding the alternative buffer management strategies available can help ensure you have the tools and resources necessary to remain competitive in today’s growing bioprocessing industry.

• Bioprocess Sampling Case Study

  A GMP-compliant, novel process sampling solution for taking multiple conical tube samples at varying time points results in immediate process efficiency and sterility assurance.

• Global Single-Use Supply Chains: Managing Risk, Minimizing Complexity

  Biopharma manufacturers can benefit by adopting a global single-use supply chain strategy early in the drug development life cycle and carefully evaluating their single-use equipment and materials suppliers.