Repligen Process Analytics

  1. Assessing mAb Quality Through Direct Spent Media Analysis 1/17/2025

    Learn about an innovative tool that offers direct analysis of spent media, revealing key product quality attributes (PQAs) of monoclonal antibodies (mAbs) that ensure optimal mAb quality and productivity.

  2. Keeping Up With New Emerging Analytical Technology 11/4/2024

    Explore advancements in emerging analytical technologies like Process Analytical Technology (PAT) and mass spectrometry, improving drug development through enhanced bioprocess monitoring and control.

  3. Data-Driven CHO Bioprocess Optimization And Scale-Up 9/10/2024

    Learn how at-line cell culture media analysis enhances mAb production by refining nutrient feed strategies, reducing toxic metabolites, and improving yields while lowering costs.

  4. Amino Acid Analysis Indicates Metabolic Differences In MCB CAR T-Cells 7/26/2024

    Exploring the metabolic differences in CAR T-cells activated with multi-cytokine backpacks (MCBs) reveals correlations between CAR T-cell activation, nutrient metabolism, and efficacy.

  5. Instant PAT Implementation Across Cell Lines, Media, And Scales 7/26/2024

    Explore how MAVERICK’s Raman-based technology delivers instant, reliable measurements of glucose, lactate, and biomass across diverse cell lines, media, and scales.

  6. Real-Time Monitoring Of Key Bioprocess Parameters 5/22/2024

    The success of this experiment shows how the integration of Process Analytical Technology probes into bioreactors can enhance process understanding and enable precise bioprocess monitoring and control.

  7. Continuous Monitoring And Control Of Glucose And Lactate 5/22/2024

    This experiment demonstrates that continuous real-time monitoring of glucose and lactate and dynamic glucose feed control to a low-level set-point leads to improved process and product parameters.

  8. Analyzing Critical Quality Attributes Of Monoclonal Antibodies 5/22/2024

    Use microchip CE-MS technology to achieve quicker peptide mapping analysis, high sample reproducibility, and low artificially induced modifications.

  9. In-line, Raman-Based PAT Solution For Monitoring And Control 5/22/2024

    With an in-line, Raman-based PAT solution you can monitor and control several critical process parameters (CPP) to maintain optimal cell culture conditions.

  10. Instant Implementation Of Raman-Based Monitoring 4/9/2024

    This platform, based on Raman technology with a de novo approach, operates as effortlessly as a pH-meter, providing real-time measurements of key process parameters such as glucose, lactate, and biomass.