Repligen Process Analytics

  1. Comparison To And Advantages Over Traditional Chemometrics Models 4/5/2024

    As Raman spectroscopy, with partial least squares (PLS) models, becomes more popular in bioprocesses applications it's important to recognize the challenges this approach presents.

  2. Analyzing Serum-Free Media For Cell Therapy Applications 3/14/2024

    Identifying critical factors and their concentrations with an eye towards designing an ideally formulated, defined serum-free medium should be carried out using rational and systematic approaches.

  3. Metabolite Analysis In Cell Therapy Development 3/14/2024

    Understand the importance of metabolic analysis in cell therapy, optimizing cell culture media formulations, and enhancing the effectiveness of CAR-T cell therapy and stem cell transplantation.

  4. Now Starts Now: The Future of Glucose And Lactate Measurement 10/4/2023

    Explore a platform that addresses the challenges of on-line nutrient and metabolite monitoring and control.

  5. On-line Measurement Of Glucose & Lactate With Automated Feedback Control 10/3/2023

    Achieve continuous, on-line monitoring with measurements as often as every two minutes, with no loss of bioreactor volume and no risk of contamination.

  6. Enabling Real-Time Process Control 10/3/2023

    Defined control strategies enable more intensified and stable cell culture processes such as perfusion which may see dramatically improved productivity.

  7. Glucose And Lactate Raman-Based Monitoring System 9/27/2023

    Evaluate the consistency, linearity, and specificity of a plug-and-play, in-line, Raman-based PAT solution that typically provides measurements with a precision of <0.1 g/L for both glucose and lactate.

  8. In-line Monitoring Of Bioprocess Parameters For The 21st Century 9/18/2023

    Review the current state of several optical technology approaches and their associated strengths and limitations along with new and transformative means to instantly implement in-line monitoring.

  9. Addressing Upstream Cell Culture Challenges As A Community 6/14/2022

    John Hopkins University's Michael J. Betenbaugh speaks to the Advanced Mammalian Biomanufacturing Innovation Center's work with new data sources to improve process modeling.

  10. Mass Spectrometry For Biopharmaceutical Process Development 6/14/2022

    Learn how at-line analytics are valuable for process modeling and biosimulation through topics such as digital design and modeling cell culture processes.