Keeping Up With New Emerging Analytical Technology

Explore how advancements in cutting-edge process analytical technologies (PAT) improve drug development, including cell and gene therapies, through enhanced monitoring and control, simplifying complex bioprocess challenges.

Highlights

Mass spectrometry-based applications range from evaluating glycan distributions in monoclonal antibody products to optimization of the cell culture process development by monitoring amino acid and metabolite consumption. Traditional Liquid Chromatography-Mass Spectrometry (LC-MS) has long been a cornerstone in this domain, renowned for its robustness and precision. Although LC-MS is highly flexible, its complexity demands significant technical expertise and method development. To streamline the process, newer PAT solutions, like REBEL, a Capillary Electrophoresis-Mass Spectrometry (CE-MS) Amino Acid Analyzer, offer simplified yet powerful methods for cell culture media analysis.

In this webinar, scientists from the U.S. Federal Drug Administration (FDA) evaluated the performance of REBEL against traditional LC-MS methods in monitoring amino acid concentrations in CHO cell culture bioreactors. 

Key Takeaways:

• Capabilities & Limitations: Understand the unique attributes of the Amino Acid Analyzer and its targeted approach for high-throughput media analysis.
• Platform Comparison: Compare the CE-MS Amino Acid Analyzer to traditional LC-MS methods in terms of ease of use, flexibility, and application-specific effectiveness.
• Data Quality & Resource Efficiency: Evaluate the trade-offs, operational ease, and resourcefulness of each analytical platform for faster, higher-quality results in cell culture process optimization.

This webinar is a must-watch for anyone looking to leverage the latest analytical advancements for efficient and reliable bioprocess insights.