Insights On Upstream Manufacturing
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In Vitro Vs In Vivo: A History Of Modern Cell Culture
3/8/2024
Explore the origins of modern cell culture as well as the advantages and disadvantages of in vitro and in vivo studies.
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High-Titer rAAV Production In Bioreactors Using Producer Cell Lines
3/6/2024
Here, we detail the upstream process development and optimization for an AAV8-GFP proof-of-concept (PoC) producer single cell clone (SCC) in both batch and perfusion modes.
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Producer Cell Line For Large-Scale Viral Vector Manufacturing
3/6/2024
Embrace the future of gene therapies and overcome challenges in large-scale viral vector manufacturing with a one-step process that ensures robustness and scalability.
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Cost Modeling Comparison Of Bioreactors To Produce Adherent Cell Products
3/6/2024
This study employs BioSolve software, a reference for cost analyses in the biopharmaceutical industry, to compare the upstream manufacturing costs between multitray stacks and the iCELLis™ bioreactor.
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Plasmid Engineering To Improve AAV Productivity And Packaging Efficiency
3/5/2024
Review how you can significantly increase AAV productivity and packaging efficiency for various AAV serotypes and client-specific Genes of Interest (GOIs) at the upstream production stage through plasmid engineering approaches.
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Novel Engineered Plasmids, Optimized HEK293 Cell Line For AAV Productivity
3/5/2024
Lonza has further improved its platform process with the creation of engineered plasmids that afford significantly higher titers and productivity levels compared to standard systems.
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Meet An Optimized Suspension-Based Platform Technology
3/5/2024
Discover a ready-to-use, suspension-based platform technology for transient transfection of LVVs that eliminates the need to transition from small-scale adherent processes.
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The Innovator's Dilemma with Lumen Bioscience's Brian Finrow, J.D.
3/4/2024
In biotech, when "one of these things doesn't look like the other one," it can be a blessing or a curse. On one hand, scientific novelty is praised and rewarded. On the other, unfamiliarity breeds skepticism from the investment community. Brian Finrow, J.D. embraces that reality and the challenges that come with it.
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Bubbling Innovation: Dynamic Trends Shaping The Future Of Microbial Fermentation
3/1/2024
Drug developers must understand the latest trends in microbial fermentation. By leveraging innovative methods and technologies, developers can unlock new opportunities and improve patient outcomes.
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A Closed And Automated Solution For Cell Therapy Manufacturing
3/1/2024
Streamline your cell therapy manufacturing process and workflow by automating and closing your cell isolation, cell harvest, and formulation with a system designed to offer you versatility.