Millipore Sigma Bio-Expo Live November 2025: Upstream Bioprocessing

CHO CLD is time and resource intensive process. While new vectors and robotics have improved timelines and throughput, they are costly and haven’t solved the core productivity limits of traditional CHO hosts. To address this, we have developed CHOZN® Elite cell line, a production-adapted CHO cell line that delivers high-yield clones using standard plasmids and media—no expensive technology required. Clones from minipool and bulk pool workflows reached up to 13 g/L and 5 g/L respectively with the later attainable in only 80 days. Depending on the CLD method used, this new host cell line meets industrial needs by accelerating the CLD or increasing the titer leading to cost-saving process.