Insights On Upstream Manufacturing

  1. Optimizing CHO Cell Culture Using A Design Of Experiments Approach 8/6/2025

    Learn how researchers optimized CHO cell culture to boost IgG1 titer to 5.8 g/L and improve viability, which cut development time from 14 days to 12 while enhancing productivity.

  2. Tangential Flow Filtration Of LNPs Results In 10X Concentration Within 20 Minutes 8/5/2025

    Dive into a study that details how a single-pass tangential flow filtration system can achieve a tenfold concentration of liposomal nanoparticles in under 20 minutes.

  3. Harvesting In The PBS Mini 8/4/2025

    Learn efficient ways to harvest cells after a run, including pipette and bottom-port aspiration techniques.

  4. Media Exchange In The PBS Mini 8/4/2025

    Discover how to perform an in situ settle-based media exchange to optimize your cell culture and improve cell growth.

  5. Sampling In The PBS Mini 8/4/2025

    Learn how to accurately sample from the PBS Mini bioreactor. Discover critical steps for representative samples, including optimal mixing and collection techniques.

  6. Inoculation In The PBS Mini 8/4/2025

    Learn how to inoculate the PBS Mini bioreactor. Discover best practices for adding supplements and cells, ensuring gentle handling and optimal mixing for your cell culture.

  7. Batching In The PBS Mini 8/4/2025

    Learn how to properly batch your cell culture vessel, equilibrating media to create a stable and consistent environment for optimal cell growth.

  8. Meet The PBS Mini Vertical-Wheel Bioreactor 8/4/2025

    Discover a scaled-down bioreactor offering superior, gentle mixing in 60-100mL and 300-500mL working volumes. Learn about its key features and universal base.

  9. Producing MSC-Derived Cell Therapies From Isolation To Large-Scale Expansion 8/4/2025

    Explore the journey of producing MSC-derived cell therapies, from initial isolation and expansion to final product formulation and storage, and learn how to optimize each step.

  10. Cell-Based Screening: Accelerating Therapeutic Development 7/29/2025

    Discover how advanced transfection technology can accelerate therapeutic development. Explore faster, more flexible cell-based screening assays, including mammalian display, to optimize your research.