Insights On Upstream Manufacturing

31. Enabling MSC Harvest, Wash, And Concentration 11/17/2025

    A study demonstrates how a low-shear, closed-system centrifuge achieved over 90% MSC recovery and minimized viability loss, supporting scalable cell therapy manufacturing.

32. Advancing Biologics Development With Next-Gen Cell Line Development 11/17/2025

    Next-gen CLD utilizes transposase-mediated integration for speed and stability and employs an engineered cell line to enhance ADCC and a high-throughput assay for early glycosylation control.

33. Rethinking Peptones As First-Line Optimization Tools 11/14/2025

    Peptones enhance CHO cell growth, viability, and yield, offering a fast, low-risk way to improve bioprocess performance without major process changes.

34. Multispecific Antibodies: Key Challenges And Solutions To Enable A New Frontier In Cancer Treatment 11/14/2025

    Multispecific antibodies are a newer class of cancer therapeutics addressing tumor complexity. Learn about the design, manufacturing, and regulatory challenges and integrated solutions accelerating their development.

35. Simplify Your Cell Culture Processes 11/13/2025

    Discover bioreactors that combine fast setup, robust design, and scalable performance to streamline cell culture workflows, which help you move from uncertainty to control, no matter your molecule.

36. Understanding Adeno-Associated Virus Vector Impurities 11/13/2025

    AAV vectors hold promise for gene therapy, but removing product-related impurities remains a challenge. Learn how cell line development and process optimization are advancing rAAV production.

37. Cell Culture Media Demystified For Performance, Quality, And Innovation 11/13/2025

    Cell culture media isn’t one-size-fits-all. Learn how media composition, customization, and analytics can dramatically improve cell growth, productivity, and product quality for complex processes.

38. Accelerate Your pDNA And mRNA Process Development 11/13/2025

    Explore a structured approach to optimizing and scaling plasmid DNA production using E. coli, with insights into key growth parameters, benchtop feasibility, and pilot-scale performance.

39. Cell Culture Media Mixing In A Benchtop Single-Use Mixer 11/13/2025

    Explore how efficient powder-liquid mixing and sterile filtration preserve media integrity and support reproducibility in biopharmaceutical workflows, with promising scalability for larger-volume applications.

40. Scientific Poster: Driving High-Titer Productivity And Faster Timelines 11/13/2025

    Accelerated cell line development delivers high-titer biologics in weeks, supporting diverse modalities with robust analytics, scalable productivity, and proven stability across 60+ generations.