Insights On Upstream Manufacturing

  1. Discover The Benchtop DynaDrive Single-Use Bioreactor 8/20/2025

    Ready to transform your process development? Introducing the 5 L Thermo Scientific DynaDrive Single‑Use Bioreactor (S.U.B.), now available! Experience the same bioreactor design from bench to commercial and re‑imagine scalability in process development.

  2. Optimizing VLP Manufacturing For Gene Editing By GMP-Compliant Flow Electroporation® 8/20/2025

    Learn how a novel approach to VLP manufacturing can overcome common scalability and consistency issues, enabling high yields and potent gene editing in a single day.

  3. Scalable Electroporation Optimizes Transposon Delivery In CAR T Cell Manufacturing Workflows 8/20/2025

    Learn how electroporation can be used to efficiently engineer T cells for CAR T cell manufacturing workflows with piggyBac™ transposons while maintaining high viability and cell yield.

  4. Time To Intensify: Taking mAb Manufacturing To The Next Level 8/19/2025

    Explore how process intensification can revolutionize monoclonal antibody manufacturing to boost productivity, cut costs, and enhance sustainability with scalable strategies and real-world results.

  5. Cell Line Development For Bispecific Antibodies 8/18/2025

    See how the recently described cell line development paradigm shift, enabled by the Leap-In transposon platform, can extend to the development of bispecific monoclonal antibody-producing cell substrates.

  6. Keys To Achieving Unparalleled Flexibility In CHO Based Bioproduction 8/16/2025

    The dynamic growth and pace of change observed in novel mAb formats and cell and gene therapies emphasizes that biomanufacturing innovation is essential to deliver scale, speed, and sustainability.

  7. Building A Biomanufacturing Ecosystem For Supply Agility Starts Early 8/16/2025

    Unprecedented capital investments of >$8bn expand capacity to improve patient access. Going beyond expansions, learn more about a holistic, globally harmonized operational ecosystem.

  8. Accelerate Your Path To The Clinic: Custom Cell Culture Media Solutions 8/15/2025

    A strategic approach to cell culture media is essential for success. Learn how to get a head start toward clinical readiness and avoid future hurdles with optimized media.

  9. An Alternative Genetic Engineering Tool In CHO Cells 8/15/2025

    Discover how transposon technology is being reimagined as a precise genetic engineering tool to create high-performing CHO cell lines for biotherapeutic production with enhanced metabolic and glycan profiles.

  10. Developing An In Vivo CAR-T With Interius BioTherapeutics' Sianny Christanti and Babu Medi, Ph.D. 8/12/2025

    On this episode of Better Biopharma, Interius BioTherapeutics’ Sianny Christanti and Babu Medi, Ph.D., explain how the company is re-engineering a lentiviral vector to enable INT2104, its off-the-shelf, in vivo CAR T-cell therapy. They discuss the vector's design and its manufacturability, as well as the analytical and regulatory challenges of bringing this first-in-human therapy to the clinic.