Insights On Upstream Manufacturing

  1. From Lab To Commercialization: Simplifying Bioprocess Scale-Up 12/16/2025

    Explore how unique cuboid geometries and advanced mixing dynamics create consistent performance from the bench to commercial manufacturing, ensuring flexibility and improved productivity.

  2. Enhancing Lentiviral Vector Titre By Limiting Auto-Transduction 12/15/2025

    Limiting auto-transduction with Additive X boosts lentiviral vector titres by 4.2-fold, reduces reintegration events, and optimizes continuous production processes for advanced cell therapy applications.

  3. Lentiviral Vector Upstream Process 12/12/2025

    Scalable lentiviral vector production is moving beyond adherent systems. Learn how streamlined workflows enable linear scale-up in stirred-tank bioreactors for cost-effective gene therapy manufacturing.

  4. Lipid Nanoparticles Boost CRISPR HDR Gene Insertion in Human T Cells 12/12/2025

    Lipid nanoparticles enable precise, non-viral gene editing in T cells to achieve high HDR efficiency and viability in scalable workflows. Explore how this approach overcomes viral vector limitations.

  5. Hear From The Experts: LNPs Driving The Future Of Cell Therapy 12/12/2025

    Explore how lipid nanoparticles are driving breakthroughs in cell therapy, from mRNA-based immune cell engineering to genome editing for CAR T cells and HSPCs from leading experts.

  6. Building A Biomanufacturing Ecosystem For Supply Agility Starts Early 12/9/2025

    A unified, modular biomanufacturing ecosystem combining rapid CLD, flexible purification, and scalable global capacity can accelerate production and strengthen supply agility amid rising demand.

  7. Efficient Stem Cell Expansion In Bioreactors For Immunotherapy 12/9/2025

    A scalable bioreactor process enables efficient expansion of cord blood-derived HSCs and NK cell differentiation, delivering high purity and strong cytotoxicity, advancing immune cell therapies.

  8. Advances In mAb Purification With Optimized Membrane And A New Screen 12/9/2025

    Optimized membranes and channel geometry accelerate mAb purification, cutting process times while maintaining product integrity. Discover how these advancements improve scalability and sustainability.

  9. MES Apps Built For Speed And Seamless Integration 12/9/2025

    Digitize bioprocess workflows to achieve consistent, paper-free execution that deploys up to 66% quicker than traditional MES with a cloud-based, no-code platform built for single-use bioprocessing.

  10. Insights To Sustainable Signaling Devices With Bioluminescent Bacteria 12/5/2025

    A protocol for scaling a bioluminescent marine strain is validated, revealing atypical light kinetics that necessitate an immediate harvesting window for maximum performance.