Insights On Upstream Manufacturing
-
Find The Right T Cell Expansion And Phenotype Balance For Cell Therapy
3/22/2024
Explore this study that works to determine the optimal concentrations of IL-7 and IL-15 for T cell expansion, as well as how to produce the desired phenotype while requiring less protein.
-
Touch-Free T Cell Expansion With A Fill-And-Forget Workflow
3/22/2024
Explore a bioreactor for large-scale, low-cost immune cell therapy manufacturing paired with a "fill-and-forget" workflow and discover how robust T cell expansion can be achieved.
-
XOFLX™ Lenti Platform: Stable Lentiviral Vector Production Cell Lines Yield LVV Titres Comparable To The Four-Plasmid Process
3/21/2024
LVV manufacturing processes remain a significant hurdle for sponsors. Review the potential of a platform of packaging and producer cell lines designed to enhance LVV manufacturing efficiency.
-
Development And Optimization Of Suspension-Adapted 293T Cell Line
3/21/2024
Learn how an adapted cell line can reduce costs and improve scalability in the production of lentiviral vectors for CGTs and examine its potential to produce GMP-grade lentiviral vectors.
-
Scale Up Strategy For Oncolytic HSV-1 Vector Manufacturing
3/21/2024
Discover how a novel, large-scale production method for herpes simplex virus type-1 vectors has the potential to accelerate the progress of gene therapy and bring it closer to widespread application.
-
Cell Line Development For High-Titer Lentivirus Vector Production
3/21/2024
Explore a groundbreaking method to significantly enhance LV vector yield using engineered HEK293T cells. This approach paves the way for more efficient and large-scale production of LV vectors.
-
A Launchpad For Scalable Systems In AAV Gene Therapy Manufacturing
3/21/2024
Identifying a trusted supplier that can address the myriad of challenges that accompany development for AAV-based drugs is critical to securing an asset’s ultimate commercial success.
-
Enhancing Quality By Employing Cell Line Replacement, Process Optimization
3/19/2024
Explore how the various proprietary platforms and in-house expertise fit together to enable a range of comprehensive options that can be adapted to fit development strategies.
-
GMP-Compliant Production Lines Of Plasmid
3/19/2024
The OBiO Intelli-M GMP manufacturing site has three production lines of prokaryotic cell culture plasmid for commercial manufacturing, including a single-use whole process production line and two stainless steel production lines.
-
A New Horizon In AAV cGMP Gene Therapy Manufacturing
3/18/2024
For cell expansion to occur, we use the world-leading cell line: Pro10™ by AskBio. Viralgen is the only company in the world with a license to manufacture for third parties.