Insights On Upstream Manufacturing

  1. Streamline Your AAV Process With A Production Platform 10/6/2025

    AAVs are reshaping gene therapy, but scaling production introduces complexity. Learn how upstream process optimization can improve yield, consistency, and speed to meet growing demands.

  2. From Seaweed To Scale-Up: IBioIC's Journey With Fermentation Technology 10/3/2025

    The circular bioeconomy requires advanced bioprocess scale-up capabilities. Access to flexible, user-friendly pilot-scale equipment is vital for companies to move from lab-bench innovation to commercial reality.

  3. Assessing The Impact Of Manipulation Of Fermentation Broth On Fungal Biomass 10/3/2025

    Explore how adding Iron and B12 to fungal fermentation media increases nutritional content and impacts the biomass's texture and flavor profile, optimizing production for novel food applications.

  4. Confidently Scaling-Up Microbial Fermentation: Overcoming Common Challenges 10/3/2025

    Successful microbial scale-up hinges on ensuring process consistency, optimizing yield, and simplifying compliance. Learn strategies to overcome key challenges in bacterial, fungal, or yeast fermentation.

  5. Complex Antibody Expression - Challenge Accepted 10/2/2025

    Explore how tailored cell line development strategies are enabling high-yield production of complex biologics and reveal how automation and data modeling drive success in CHO cell line development.

  6. Scalable Strategies For Intensified Viral Vector Production In HEK293 Cell Culture 10/1/2025

    Learn a strategy for scalable bioprocessing and media optimization that drives intensified viral vector production. Achieve high cell density, excellent viability, and consistent AAV titers from 50mL to 5L.

  7. Chemically Defined HEK293 Viral Feed Boosts Viral Vector Production 10/1/2025

    Discover how a chemically defined viral feed can boost AAV titers by up to 8-fold, supporting multiple serotypes and both suspension and adherent HEK293 cell lines, simplifying scalability.

  8. Simplify Cell Line Development 10/1/2025

    Explore a streamlined method for isolating viable single cells using microfluidic dispensing and whole-well imaging that is designed to improve clonality, cell health, and reproducibility.

  9. Optimization And Scale-Up Of A Plasmid DNA Production Process 9/30/2025

    Optimizing pDNA production in E. coli requires strategic media selection and scale-up planning. Explore a study that identifies ideal conditions for high-yield manufacturing.

  10. Genetically Modified MSCs For The Treatment Of GvHD 9/30/2025

    Discover how genetically engineered MSCs are significantly advancing GvHD treatment. Learn about preclinical success with CXCR4-IL10-MSCs and the process for scaling up their GMP production.