Insights On Downstream Manufacturing

  1. CaptureSelect Affinity Chromatography 11/4/2025

    30-second video sharing a visualization of our CaptureSelect affinity chromatography capability. The target protein binds with VHH molecules immobilized on the chromatography beads, non-target proteins are removed, and the eluted fraction contains a high yield of purified target protein.

  2. Optimization Of Anion Exchange Purification For The Large-Scale Production Of Plasmid DNA 11/4/2025

    In this webinar, we discuss pDNA purification, including how to identify optimal conditions for various chromatography media and optimize recovery and impurity removal.

  3. Use Cation Exchange Chromatography For High Yields In Vaccine Production 11/4/2025

    Learn how to achieve high yields in vaccine production by using Cation Exchange Chromatography for purifying SARS-CoV-2 spike proteins. This method provides high purity and minimizes protein aggregates.

  4. A Simple Method For Cell Growth Media Preparation 11/3/2025

    Explore how powder media and sterile fluid handling can reduce contamination risk and improve efficiency in viral vector production, especially for HEK293-based AAV workflows.

  5. Leveraging 3 Distinct Resins To Provide Effective Impurity Removal For mAbs And Novel Antibody Derivatives 11/3/2025

    Due to the complexity of bispecifics, Fc-fusion proteins, and Fab fragments, their manufacturing poses added purification challenges and requires a robust toolkit of purification techniques.

  6. THESYS ACS ERGO Column Packing And Unpacking 10/31/2025

    The time between batches for oligonucleotide synthesis has long been a bottleneck, consuming valuable lab time with complex, multi-step column maintenance. A new column design can simplify this process.

  7. Overcoming Scale-Up Challenges In Viral Vector TFF 10/29/2025

    Discover how a tailored TFF solution delivers a scalable, high-yield process that integrates smoothly with existing infrastructure and maintains regulatory compliance.

  8. Implementing A Versatile Mixing System To Drive Down Costs 10/29/2025

    Learn how a CDMO reduced capital expenses and operational complexity by adopting an all-in-one mixing solution that supports every stage of production and a wide range of volumes.

  9. Optimize DNA Clearance In High-Salt, GMP-Grade Purification Processes 10/28/2025

    Explore how salt-active endonucleases overcome DNA clearance challenges in viral vector purification by digesting down to 3–5 nucleotides and performing reliably in high-salt conditions.

  10. Strategies For Enhancing Bioprocessing Productivity 10/27/2025

    New complex therapeutics demand a shift from traditional bioprocessing. Learn how innovative strategies and resin technologies can help you manage costs and efficiently scale production.