Insights On Downstream Manufacturing

  1. From Syringes To Wearables: Formulation's Impact 1/21/2026

    High‑concentration biologic formulations for prefilled syringes and on‑body devices enable easier self‑administration, reduce treatment burden, boost adherence, and address complex formulation challenges.

  2. Turbocharging pDNA Production: CDMO Case Study In Optimization 1/21/2026

    Optimize your plasmid DNA workflows with insights from Forge Biologics. Discover how TFF advancements cut processing time by 300% while improving RNA removal and DNA quality.

  3. The Science of Selection: Choosing The Right Hollow Fiber Filter 1/20/2026

    Discover how hollow fiber tangential flow filtration enhances downstream bioprocessing with efficient ultrafiltration and diafiltration, reduced fouling, and scalable performance.

  4. Sterile Injectables: Why Innovation Matters More Than Ever 1/15/2026

    New technologies and regulatory changes are shaping safer, more efficient filling processes. Discover why innovation is key to protecting patients and advancing therapies.

  5. Accelerating The Seed Train: Enabling N-1 Intensification 1/15/2026

    Discover how N-1 intensification shortens production timelines and improves cell viability by replacing traditional filtration with automated, low-shear separation techniques to achieve higher seeding densities.

  6. Multi-Column Chromatography For Efficient Polishing Purification 1/14/2026

    Boost downstream efficiency with multi-column chromatography for polishing to achieve higher productivity, reduced resin costs, and automated operation while maintaining purity and recovery.

  7. Enhanced Flow Kit Performance With Leak And PUPSIT Testing 1/13/2026

    Sterile drug filtration demands rigorous integrity testing to prevent contamination. Learn how PUPSIT and in situ leak testing strengthen compliance with EU GMP Annex 1 and ensure reliable manufacturing.

  8. Automated PUPSIT For Drug Product Applications 1/13/2026

    Automated filtration systems streamline PUPSIT, leak testing, and integrity checks to ensure sterile drug product processing. Learn how these methods improve contamination control and compliance.

  9. Wetting Recommendations For Successful Filter Integrity Testing 1/12/2026

    Discover best practices for hydrophobic and hydrophilic filters, troubleshoot failures, and optimize wetting in stainless steel and single-use systems to ensure process reliability and product quality.

  10. Optimized Product Recovery Using The Drug Product Filtration System 1/12/2026

    Explore strategies to maximize drug product recovery during sterile filtration, minimize hold-up volume, and reduce dilution after PUPSIT to ensure higher yield, improved efficiency, and less waste.