Insights On Downstream Manufacturing

  1. Predicting Viral Clearance Through CHO-RVLP And MVM-Mock Viral Particles 2/11/2025

    Reduce the cost and complexity of viral clearance validation with non-infectious surrogates. Learn how CHO-RVLP and MVM-MVP enable safer, more efficient biopharmaceutical process development.

  2. Utilizing Retrovirus-Like Particles (RVLP) To Evaluate Viral Clearance For Multiple Modes Of Separation 2/11/2025

    This study demonstrates that Retrovirus-like particles (RVLPs) can be used to accurately assess viral clearance, providing a valuable tool for the development of biopharmaceutical manufacturing processes.

  3. A Cost-Effective Alternative To Traditional Protein A Resin Chromatography 2/6/2025

    Examine this cost-effective, efficient alternative to traditional Protein A resin chromatography for mAb production to enhance productivity and reduce costs.

  4. Scalable Expansion And Downstream Processing Of High-Quality hiPSCs 1/31/2025

    Learn about a scalable, microcarrier-based 3D culture process for expanding hiPSCs to 10L, yielding over 10 billion cells while maintaining quality.

  5. The Next Frontier In mRNA: Modular Manufacturing For Scalable RNA-LNP Therapies 1/29/2025

    Explore constructing a modular RNA-LNP GMP facility using Cytiva's FlexFactory™ process train in a KUBio™ environment to scale RNA-LNP therapies.

  6. Ensuring Homogeneity In Biopharmaceutical Aliquotation 1/17/2025

    Tired of manual manipulation risks in biopharmaceuticals? Discover how automated homogenization ensures consistent cell counts and concentration levels, improving patient safety and process reproducibility.

  7. The Leader In Fill/Finish 1/17/2025

    Discover how our advanced fill-finish manufacturing capabilities can elevate the success of your project, streamlining processes and enhancing quality at every step.

  8. Getting More From Your Buffer Management Strategy 1/17/2025

    A drug manufacturer was facing challenges in buffer management. By implementing innovative inline buffer formulation technology, they were able to save space, increase efficiency, and become more sustainable.

  9. Toward A Gene Therapy Platform: What's The Best Format Of TFF? 1/13/2025

    Evaluate tangential flow filtration (TFF) formats and membrane chemistries for AAV gene therapy processing, assessing performance, scalability, economy, and closed processing options.

  10. Solvent-Free Purification Of D84-mer Oligonucleotide Using Capto™ PlasmidSelect Resin 1/13/2025

    Discover a solvent-free process using Capto PlasmidSelect and Capto Q ImpRes resins. They enable high-purity, scalable purification of long oligonucleotides, achieving more than 95% of full-length product purity.