Insights On Downstream Manufacturing

  1. Merck Process Transfer And Scale-Up Of Batch Protein A 6/30/2025

    Explore cost-saving innovations in purification using a system that achieves consistent product quality and yield while significantly reducing resin use and enhancing large-scale efficiency.

  2. Efficient AAV Purification With AAVx And AAV9 Magnetic Beads 6/30/2025

    Explore an alternative to chromatographic affinity capture that eliminates the need for universal nuclease treatment by utilizing magnetic beads with ligands specific to AAV.

  3. Enabling Continuous Manufacturing For CAR-T And LNP-Based Therapies 6/27/2025

    Breakthrough therapies are challenged by complex, batch-based manufacturing. A novel, integrated system enables continuous processing, improving consistency and reducing manual handling for advanced modalities.

  4. Recombinant Protein Process Development And Scale-Up 6/26/2025

    Discover a resin for recombinant protein purification with a standardized protocol that streamlines workflows from lab to production, which saves time and enhances efficiency across development stages.

  5. Optimize Your mAb Capture And Polishing With The Latest Resins And Tips 6/26/2025

    Discover the latest innovations in monoclonal antibody purification and explore resin selection strategies to optimize product quality and improve process efficiency.

  6. Smarter Cell Washing And Pre-Formulation For Allogeneic Therapies 6/26/2025

    Discover common pitfalls in cell washing and pre-formulation, including incomplete contaminant removal, manual handling, and throughput issues that compromise product quality and efficiency.

  7. Pre-Use Post Sterilization Integrity Testing (PUPSIT) Overview 6/18/2025

    Successfully implementing PUPSIT requires balancing regulatory compliance with operational efficiency. Gain insights into regulations and expert solutions to help streamline your manufacturing process.

  8. Enabling Development Of Scalable, Personalized Cell Therapies For Solid Tumor Treatments 6/16/2025

    Harnessing the body’s own immune system, researchers are developing personalized cell therapies to target solid tumors, using a patient’s unique mutations to create powerful, individualized treatments.

  9. Manufacturing CAR T Cell Therapies: Challenges, Insights And Solutions 6/16/2025

    Manufacturing patient-specific cell therapies is a complex, multi-step process. Addressing key hurdles in production time, scalability, and cost is crucial to making these vital treatments more accessible.

  10. Next-Gen Biomanufacturing: Process Intensification For mAb Production 6/13/2025

    Intensified processes, omics-driven media, and advanced bioreactors can boost efficiency and scalability in mAb production.