Bioprocessing Application Notes & Case Studies

1. WuXiHigh 2.0 Delivers A 180 mg/mL Formula 3/26/2026

   This case study shows how smart formulation and integrated development achieved a stable 180 mg/mL biologic for subcutaneous delivery, for teams tackling concentration issues.

2. Rapid Assessment Of Fab-VHH Expression Application Of The Pfast™ Program 3/25/2026

   A systematic screen of 40 expression configurations delivered production-ready Fab-VHH conditions within 10 days, achieving 570 μg/mL titers with light chain-first orientation.

3. High-Throughput Pyrogen Testing In A Multimode Microplate Reader 3/20/2026

   Explore a faster, high‑sensitivity approach to pyrogen detection that uses an NF‑κB reporter system to measure both endotoxin and non‑endotoxin contaminants to enable shorter workflows.

4. Particle Data Collection And Interpretation For ISO Cleanrooms 3/19/2026

   Transition from periodic sampling to continuous monitoring. Learn to establish risk-based alert limits and use N:M trending to maintain a true state of control in critical cleanroom zones.

5. QC In The Whole Genome Sequencing Library Preparation Workflow 3/19/2026

   Take a look at how electrophoresis systems differ in sizing accuracy and why those distinctions matter for assessing high‑molecular‑weight DNA and protecting QC checkpoints across sequencing workflows.

6. Comparison Of Different Methods To Isolate HMW DNA From Bacteria 3/19/2026

   Different extraction methods produce dramatically different DNA sizes and qualities, directly affecting long‑read sequencing results. See how performing early QC can improve sequencing success.

7. Separation Of cfDNA With An NGS Kit On Fragment Analyzer Systems 3/19/2026

   Learn how precise sizing methods reveal nucleosome patterns in cfDNA and help distinguish true signal from extraction‑related artifacts for more reliable genomic analysis.

8. Sample Quality Control In The Whole-Genome Sequencing Workflow 3/19/2026

   See how consistent QC checkpoints show how even degraded samples can produce strong sequencing results when monitored with reliable sizing, quantification, and workflow‑specific thresholds.

9. Method Development For Forced Degradation Of GLP-1 Agonist 3/18/2026

   Gain insight into how a systematic approach reveals impurity behavior, strengthens selectivity, and refines chromatographic conditions to build a reliable degradation method for a GLP‑1 agonist.

10. Denaturing SEC-MS Analysis Of High Molecular Weight Impurities 3/18/2026

    Look at how denaturing SEC‑MS uncovers low‑level oligomers and truncated variants in GLP‑1 peptides, offering clarity on impurity profiles and supporting confident assessment of molecular integrity.