Bioprocessing Application Notes & Case Studies

1. Aggregate Analysis Of Insulin Analogues 12/11/2025

   Therapeutic peptide purity is critical. Learn about SEC analysis of high molecular weight impurities in Insulin Glargine and Insulin Lispro to ensure product quality and safety.

2. Assessing Quality AAV Attributes Including Aggregation And Capsid Load 12/11/2025

   Assessing AAV critical quality attributes (CQAs)—like aggregation and the full-to-empty capsid ratio—is vital for gene therapy safety and efficacy. See how SEC-MALS enables reliable analysis.

3. Insights To Sustainable Signaling Devices With Bioluminescent Bacteria 12/5/2025

   A protocol for scaling a bioluminescent marine strain is validated, revealing atypical light kinetics that necessitate an immediate harvesting window for maximum performance.

4. Accelerate Drug Discovery With Real-Time Cell Interaction Insights 12/5/2025

   Decoding immune cell interactions reveals critical insights for cancer therapy. Advanced imaging and spectral analysis enable precise identification of synapses, accelerating immuno-oncology research.

5. AOC GMP Manufacture For A FIH Study 12/5/2025

   Successful development of AOCs for FIH studies requires robust GMP processes and efficient scale-up. A key step is careful management of a multi-day conjugation process with vital in-process checks.

6. AOC Conjugation – mAb With SiRNA 12/5/2025

   See how to overcome risks in mAb-SiRNA conjugation, including disulfide scrambling and SiRNA deconjugation, by using advanced chemical and operational solutions to improve material yield and stability.

7. The Proven Supplement For CAR-T Solid Tumor Cytotoxicity 12/4/2025

   Optimize cell culture for solid tumor research. Replacing traditional serum can significantly enhance CAR-T cytotoxicity, improve consistency, and streamline the path to GMP-ready workflows.

8. Optimized Transient Transfection Platform: AAV Program From Gene To GMP 12/2/2025

   Achieve faster AAV gene therapy progress by adopting a unified platform for manufacturing. Accelerate your program to GMP readiness with up to 9x higher titers and robust, high-quality full capsid yields.

9. The Art Of Phosphitylation 11/24/2025

   Phosphorylation is key for bioactives, with phosphoramidites favored for high selectivity. Discover how choosing specific protecting groups and new technologies fine-tunes the synthesis process.

10. Vaccine Fill Line Operations 11/24/2025

    Learn how adopting a harmonized, risk-based validation strategy across global sites can reduce operational readiness timelines and drive improvements in equipment effectiveness and regulatory compliance