Bioprocessing Application Notes & Case Studies

1. LYO Cycle Development Ensures Success For Oncology Drug Scale-Up 5/14/2026

   An optimized lyophilization cycle removes excess moisture during scale‑up by adjusting drying for larger equipment, improving stability, maintaining efficiency, and supporting clinical validation.

2. Accelerating Development Of A Unique Molecule To Treat Lung Cancer 5/14/2026

   Process development and optimization enabled efficient scale‑up of a complex lung cancer therapy, improving yields, reducing costs, and supporting rapid clinical and commercial progress.

3. Enabling A Four-Fold Increase In Titer For mAb Manufacturing 5/14/2026

   A platform-based upstream strategy increased monoclonal antibody titers fourfold, improving yield, efficiency, and scalability via optimized clones, process design, and rapid scale-up.

4. How A Global Biosimilars Company Cut Manual Data Errors By 50% 5/8/2026

   Learn how a global biopharmaceutical leader halved transcription errors and integrated over 350 instruments to accelerate the development of high-quality, clinically proven biosimilars.

5. Native SEC-MALS Characterization Using A Chromatography Data System 5/7/2026

   Native SEC‑MALS offers a calibration‑free way to accurately characterize peptide oligomers, helping scientists distinguish true higher‑order structures while avoiding bias.

6. Microflow Columns Boost GLP-1 Sensitivity And Reduce Solvent 5/7/2026

   Microflow chromatography offers a practical way to boost GLP‑1 assay sensitivity while cutting solvent use. See how 1.0 mm columns improve peak response without sacrificing chromatographic performance.

7. Predicting Performance Of Lotions Through Rheological Characterization 5/6/2026

   Rheological testing shows how small formulation differences influence spreading, flow, and feel during use. With minimal sample volumes, these methods connect lab measurements to real‑world performance.

8. Rheology Is An Accurate Predictor Of Pharmaceutical Lotion Stability 5/6/2026

   Rheological creep testing provides a rapid way to predict pharmaceutical lotion stability by linking steady-state viscosity to particle settling behavior, enabling reliable shelf-life estimates.

9. Rapid Selection Of High-Performance CHO Basal And Feed Media 5/5/2026

   A CHO-S bispecific antibody program needed a better basal and feed media combination. Learn how the screening of 180 conditions in 12 weeks identified one that delivered 38% higher titers.

10. Development Of An Oncology VHH-ADC Candidate Via Site-Specific Non-Canonical Amino Acid Conjugation 5/5/2026

    Homogeneous ADCs demand precise conjugation chemistry. See how 100% ncAA incorporation and 15 g/L titers were confirmed in a VHH nanobody at bioreactor scale.