Bioprocessing Application Notes & Case Studies

  1. Benchmarking Filtration Performance Of TFF Cassettes 5/30/2025

    Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.

  2. Taking A Look At AAV Production Using HEK293 In A Perfusion Process 5/28/2025

    Discover a scalable, cost-effective solution for gene therapy manufacturing with VintaProcess™ — featuring VintaCell™, VintaFect™, and fixed-bed bioreactor technology.

  3. The Evolution Of AAV Production: Scaling Through Nature Instead Of Brute Force 5/28/2025

    This study evaluates the performance and productivity of VintaProcess in addressing the persistent manufacturing challenges in AAV gene therapy production.

  4. IR Spectral Signatures Of GC, AU, And GU Base Pairing In H2O-Based Buffer By MMS 5/22/2025

    Explore a label-free approach to characterize RNA structure with high sensitivity. See how specific base pair types are resolved, providing a clearer picture of RNA folding.

  5. Tackling Allogeneic Immunotherapy's Scale-Up Bottleneck With Vertical-Wheel® Bioreactors 5/21/2025

    New bioreactor technology provides an optimal environment for shear-sensitive cells, addressing key scale-up challenges for allogeneic therapies from research to commercial production.

  6. Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs 5/16/2025

    By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

  7. Modelling TPDs Utilizing Computational And Medicinal Chemistry Approaches 5/16/2025

    Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

  8. Enabling Transfer Of Raman Calibration Models Across Bioreactor Scales 5/16/2025

    Raman spectroscopy has revolutionized manufacturing through real-time monitoring. Explore a system that enables a seamless calibration model transfer from small- to large-scale bioreactors to enhance scalability and efficiency.

  9. A Scalable Manufacturing Platform For The Purification Of Stem Cell Derived Exosomes 5/16/2025

    EV production scale increases require paired robust, scalable, and cost-effective downstream processes. Process parameters can be tailored for therapeutic exosome programs and allow for maximum exosome recovery.

  10. Top 10 Pharma Company Uses Validation Technology To Streamline CQV 5/14/2025

    Discover how a Top 10 global pharma company saved over $900K using validation technology, as well as explore their digital CQV transformation to learn how you can achieve similar results.