Bioprocessing Application Notes & Case Studies
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Achieving Environmental Sustainability In Bioprocessing
10/26/2023
Designing bioprocessing consumables has become increasingly important in the single-use space as a way to address sustainability concerns.
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Testing Cell-Based Immunotherapeutics For Microbial Contaminants
10/23/2023
In this study, two different immune cell preparations were evaluated for their compatibility with the Milliflex® Rapid System to establish a USP and EP compliant method for rapid sterility testing.
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Monitoring Industry Contamination Down To Single Particle Level
10/23/2023
Examine the benefit of using fluoropolymer film bags for the handling and storage of high value oligonucleotides- based payloads.
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Optimizing And Scaling Lentiviral Vector Production
10/23/2023
Here, we outline how the upstream and downstream workflows of the VirusExpress® platform for lentiviral vectors were optimized through the use of design of experiments and supplementary studies.
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Reducing The Level Of Host Cell Proteins In The Bioreactor Harvest
10/20/2023
Learn how MilliporeSigma helped a customer drastically reduce the level of HCPs in the bioreactor harvest prior to a production run to supply drug substance for a scheduled Phase 1 clinical trial.
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Accelerating Bulk Harvest Testing Using A CHO Animal Origin Free Virus Panel
10/19/2023
Here, we describe the Blazar® CHO Animal Origin Free (AOF) panel for rapid adventitious virus detection, a degenerate PCR-based approach to broad virus screening.
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Outsourcing Manufacturing Of Acetic Acid And Benzyl Alcohol Solutions
10/19/2023
Custom buffer solutions produced for a multinational biopharmaceutical company, enabled a fast facility expansion while still meeting the customers strict quality and regulatory requirements.
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Culturing Of Sf 9 Insect Cells With The BEVS, And SEAP Production
10/18/2023
This study analyzes the cultured Sf9 insect cell line infected with a baculovirus expressing SEAP, and compares the growth behavior and productivity in different orbitally shaken culture vessels.
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Process Transfer Of CHO Cultivations
10/17/2023
Explore the results of process-engineering characterization that demonstrate why the Minifors 2 is recommended for CHO cell culture processes but also other shear-sensitive cell types.
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The Systematic Characterization Of A Stirring Reactor
10/16/2023
This application note describes a systematic characterization of a stirring reactor and it's suitability for microbial applications.