Bioprocessing Application Notes & Case Studies

  1. Stability Screening For Colloidal Stability: Diffusion Interaction Parameter Thermal Shift Assay 4/28/2025

    Colloidal stability is one of the most important properties to control due to the propensity for biopharmaceuticals to aggregate and the subsequent potential to severely affect the drug's efficacy and patient safety.

  2. Why Cell Line Screening Is Crucial For Successful CDC Assay Development 4/28/2025

    In developing a CDC assay for therapeutic mAb characterization or QC release testing, in addition to selecting a target cell line that expresses the mAb ligand, consideration should be made to the expression of CRPs on the cell surface.

  3. Demonstration Of Scalability For A Novel Fixed Bed Reactor Platform 4/28/2025

    Designed to enable efficient scalability, a new FBR platform allows operators to use one technology, with a standardized workflow, for their process development, scale-up, and manufacturing processes.

  4. CDMO Uses Robotic Gloveless Isolator For Advanced Therapeutics 4/28/2025

    CDMOs must innovate production architectures to meet the demands of advanced therapeutics to ensure a reliable supply and compliance. Discover how these approaches advance modern medicine and improve patient outcomes.

  5. Characterizing Binding Interactions By ITC 4/24/2025

    Isothermal Titration Calorimetry is a powerful technique for analyzing biochemical binding events, which is crucial for understanding molecular interactions and enzyme kinetics in biomedical research.

  6. CAR Expression Detection Using Fluorescent Labeled Proteins, Flow Cytometry 4/23/2025

    Learn how site-specific fluorescent labeling addresses key challenges in flow cytometry-based evaluations by enhancing assay sensitivity, reducing variability, and ensuring reliable results.

  7. A Novel Patient-Derived Colorectal Cancer Organoid Platform 4/22/2025

    Patient-derived organoids are revolutionizing drug discovery by mimicking tumors and predicting therapeutic efficacy. Discover a scalable bioprocess that enhances reproducibility and cost-effectiveness to pave the way for broader adoption.

  8. IVT mRNA Encapsulation Efficiency Assessment 4/21/2025

    In vitro transcribed mRNA revolutionizes biotherapeutics, which necessitates thorough quality assessments. Discover how an analyzer system enhances encapsulation efficiency and critical quality attributes in IVT mRNA workflows.

  9. CQA Assessment Of LNP-Encapsulated IVT mRNA 4/21/2025

    Learn more about issued guidelines on Critical Quality Attributes for IVT mRNA vaccines and biotherapeutics to focus on drug substance and LNP-encapsulated drug product assessment using an analyzer system.

  10. Boost Your Lab's Performance: 3 Ways To Increase Efficiency 4/16/2025

    Maximize your research potential by overcoming workflow bottlenecks. This piece explores flexible strategies for increasing throughput and integrating automation seamlessly into your laboratory operations.