Bioprocessing Application Notes & Case Studies

  1. Sterile Filter Membrane Selection For Cell Culture Media Filtration 8/24/2026

    Membrane design and filtration capacity affect pressure, throughput, and scale-up. See how comparative testing reveals opportunities to reduce required filtration area, capsule use, and changeouts.

  2. Detect Low-Abundance GLP-1 Impurities With Greater Sensitivity 8/24/2026

    Low-level impurities can be difficult to resolve using conventional approaches. Discover how a Charged Surface 2.3 µm superficially porous Phenyl-Hexyl column enhances reversed-phase LC-MS analysis.

  3. Differentiate Challenging Site-Specific Isomeric Amino Acids 8/24/2026

    Learn how high-resolution ion mobility, pre-IMS fragmentation, and product ion analysis can resolve difficult peptide isomers and localize structural differences, supporting confident characterization.

  4. Increase Throughput For Intact Mass Confirmation And Impurity Screening 8/24/2026

    Accelerate intact mass analysis of GLP-1 analogues with automated purity calculations, sub-ppm mass accuracy, and impurity detection for consistent results in under one minute per sample.

  5. Fusion-Enabled Biosimilar Peptide Teriparatide Expression 8/24/2026

    See how high-throughput fusion partner screening identified teriparatide production strains exceeding 6 g/L expression, supporting biosimilar comparability assessment and commercial manufacturing readiness.

  6. Optimizing Liquid And Solid Mixing Across Variable Process Volumes 8/20/2026

    Discover how working volume, material type, and solids behavior affect single-use mixing performance, with practical findings on blend times, homogeneity, analytical methods, and agitation rates.

  7. Conductivity Control For Linear And Step Gradients 8/20/2026

    Examine how closed-loop conductivity control supports accurate step and linear gradients, as well as consistent chromatography performance across changing flow rates and process conditions.

  8. Scaling Cation Exchange And Affinity Chromatography Operations 8/20/2026

    See how consistent residence time, linear velocity, and gradient formation support predictable monoclonal antibody purification across column scales while preserving chromatographic performance.

  9. Evaluating Mixing Performance Across Liquids, Solids, And Powders 8/20/2026

    Analytical readings may indicate uniformity before mixing appears visually complete. Explore how material behavior, agitation, working volume, and addition methods affect mixing times.

  10. Integrated AEX And SPTFF Processing Using A Single Automated Workflow 8/20/2026

    See how integrating AEX flow-through chromatography with inline SPTFF concentration can reduce intermediate handling and process transitions while maintaining polishing performance.