Bioprocessing Application Notes & Case Studies

  1. Improving Stability Through Science-Led OSD Reformulation 10/13/2026

    A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

  2. De-Risking Complex Generic OSD Development 10/13/2026

    Complex generic tablet development requires early alignment of regulatory strategy, QbD formulation, discriminatory dissolution, and reference-scaled bioequivalence.

  3. Cell Culture Monitoring With An Innovative Analyzer 10/9/2026

    Evaluate the speed, precision, and consistency of automated bioanalyte testing, including sensor detection principles, quality controls, glucose, and lactate linearity.

  4. Method Evaluation Guidance For Transferring A Process 10/9/2026

    Moving a cell counting method between analyzers in a lab requires evidence of comparability. A structured study of suspension and adherent models tests precision and linearity against defined criteria.

  5. An Automated Cell-Processing Platform For MSC Harvest 10/7/2026

    Discover closed, automated harvest, formulation, and dispensing of umbilical cord MSCs at commercial scale, with data on viability, recovery, and filling precision, including single runs.

  6. Purification Of Antibodies With Nuvia™ wPrime 2A Media, A Scalable Hydrophobic Weak Anion Exchange Resin 10/5/2026

    Discover how mixed-mode AEX-HIC resin in flow-through mode optimizes downstream mAb purification, lowering aggregate levels to 0.7% with high monomer recovery.

  7. Protective Shell For 2D Bags: Engineered For Mechanical Protection 10/2/2026

    Protect frozen single-use bag assemblies from movement and handling stress with rigid secondary packaging, dedicated foam immobilization, and efficient plate-freezing heat transfer.

  8. A More Controlled Approach To Chromatography Scale-Up 10/2/2026

    Scaling chromatography from development to manufacturing can introduce equipment and process variability. Precise flow control, PAT, and system-level engineering help maintain consistency, improve process control, and optimize capacity.

  9. How EPR Unlocks Missing Dynamics In Pharma And Structural Biology Workflow 10/1/2026

    Uncover how EPR spectroscopy fills the conformational gap by capturing dynamic protein motions, refining Cryo-EM models, and revealing hidden structural ensembles for drug discovery.

  10. Reduce Complexity, Not Quality In CAR T Cell Manufacturing 9/29/2026

    Fragmented CAR T cell manufacturing workflows drive up costs and extend timelines. This case study quantifies what consolidating manufacturing and QC through automation actually delivers.