Bioprocessing Application Notes & Case Studies

  1. Tackling Allogeneic Immunotherapy's Scale-Up Bottleneck With Vertical-Wheel® Bioreactors 5/21/2025

    New bioreactor technology provides an optimal environment for shear-sensitive cells, addressing key scale-up challenges for allogeneic therapies from research to commercial production.

  2. Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs 5/16/2025

    By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

  3. Modelling TPDs Utilizing Computational And Medicinal Chemistry Approaches 5/16/2025

    Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

  4. Enabling Transfer Of Raman Calibration Models Across Bioreactor Scales 5/16/2025

    Raman spectroscopy has revolutionized manufacturing through real-time monitoring. Explore a system that enables a seamless calibration model transfer from small- to large-scale bioreactors to enhance scalability and efficiency.

  5. A Scalable Manufacturing Platform For The Purification Of Stem Cell Derived Exosomes 5/16/2025

    EV production scale increases require paired robust, scalable, and cost-effective downstream processes. Process parameters can be tailored for therapeutic exosome programs and allow for maximum exosome recovery.

  6. Top 10 Pharma Company Uses Validation Technology To Streamline CQV 5/14/2025

    Discover how a Top 10 global pharma company saved over $900K using validation technology, as well as explore their digital CQV transformation to learn how you can achieve similar results.

  7. Pharmacokinetic Study Of Salbutamol Through Nose Only Exposure In CD-1 Male Mice 5/13/2025

    Explore how using advanced tools like the inExpose system can provide precise measurements of lung and plasma drug concentrations to optimize inhalation therapy for pulmonary treatments.

  8. PSC Perfusion Guidance Using Vertical-Wheel Bioreactors 5/9/2025

    Unlock the potential of perfusion for pluripotent stem cell cultures. Explore key insights into achieving improved consistency and quality in your medium exchange protocols, leading to better outcomes.

  9. The Role Of Peptones In Boosting Monoclonal Antibody Production 5/9/2025

    Peptones have become a key tool in CHO cell bioprocessing, enhancing monoclonal antibody yield and quality.

  10. A Paperless Lab Simplifies, Accelerates Full Sample Lifecycle Data Management 5/1/2025

    Implementing IDBS’ ELN helped Crown Bioscience realize electronic experimental records, optimizing our business processes and helping them to be more standardized.