Bioprocessing Application Notes & Case Studies
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Glucose And Lactate Raman-Based Monitoring System
9/27/2023
Evaluate the consistency, linearity, and specificity of a plug-and-play, in-line, Raman-based PAT solution that typically provides measurements with a precision of <0.1 g/L for both glucose and lactate.
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Development Of A Novel Cell Culture Medium For AAV Production
9/26/2023
Explore the medium development process of a novel cell culture medium for AAV production with multiple HEK293 lineages, which was performed with three different HEK293 cell lines to maximize AAV titers.
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High Sequence Coverage And Confident PTM Analysis Of Biotherapeutics Using An EAD-Based Workflow
9/21/2023
Explore how a streamlined, EAD-based middle-down workflow can achieve consistent high sequence coverages of mAb subunits and confident PTM analysis in a single injection.
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Monitoring And Determining The Cause Of Antibody Discoloration Using cIEF And EAD
9/21/2023
View a study which provides additional insight into the factors that govern the discoloration of protein therapeutics and the role of AGEs in color change.
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EAD-Based Middle-Down Workflow Analysis
9/21/2023
How can a single-injection, EAD-based middle-down workflow leverage accurate mass measurement, information-rich EAD fragmentation and automated data analysis to offer confident sequence confirmation.
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CE-SDS Analysis Of Etanercept Using The BioPhase 8800 System
9/21/2023
In this study, a system with multi-capillary capabilities was used to analyze etanercept by bapillary electrophoresis-sodium dodecyl sulfate (CE-SDS).
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Accurate HC-LC Pairing And A Close-To-Nature Solution For bsAbs
9/11/2023
Examine how a proprietary technology ensures high levels of accurate HC-LC pairing without detriment to critical quality attributes such as titer, binding affinity, stability, and immunogenicity.
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mRNA-LNP Nucleic Acid Assessment From Distinct Formulations
9/8/2023
Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.
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Molecular Weight Confirmation For Length, Integrity And Impurity Analysis Of A 70-Mer Oligonucleotide
9/8/2023
Explore a workflow used to determine the molecular weight and analyze the purity of a 70-mer DNA sequence with a 3’ dT overhang.
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Assessment Of Product Quality In Upstream Process Development
9/7/2023
Simplify your capillary electrophoresis sodium dodecyl sulfate and imaged capillary isoelectric focusing workflows with an automated platform for analyzing protein size and charge during development.