Bioprocessing Application Notes & Case Studies

41. Glucose And Lactate Raman-Based Monitoring System 9/27/2023

    Evaluate the consistency, linearity, and specificity of a plug-and-play, in-line, Raman-based PAT solution that typically provides measurements with a precision of <0.1 g/L for both glucose and lactate.

42. Development Of A Novel Cell Culture Medium For AAV Production 9/26/2023

    Explore the medium development process of a novel cell culture medium for AAV production with multiple HEK293 lineages, which was performed with three different HEK293 cell lines to maximize AAV titers.

43. High Sequence Coverage And Confident PTM Analysis Of Biotherapeutics Using An EAD-Based Workflow 9/21/2023

    Explore how a streamlined, EAD-based middle-down workflow can achieve consistent high sequence coverages of mAb subunits and confident PTM analysis in a single injection.

44. Monitoring And Determining The Cause Of Antibody Discoloration Using cIEF And EAD 9/21/2023

    View a study which provides additional insight into the factors that govern the discoloration of protein therapeutics and the role of AGEs in color change.

45. EAD-Based Middle-Down Workflow Analysis 9/21/2023

    How can a single-injection, EAD-based middle-down workflow leverage accurate mass measurement, information-rich EAD fragmentation and automated data analysis to offer confident sequence confirmation.

46. CE-SDS Analysis Of Etanercept Using The BioPhase 8800 System 9/21/2023

    In this study, a system with multi-capillary capabilities was used to analyze etanercept by bapillary electrophoresis-sodium dodecyl sulfate (CE-SDS).

47. Accurate HC-LC Pairing And A Close-To-Nature Solution For bsAbs 9/11/2023

    Examine how a proprietary technology ensures high levels of accurate HC-LC pairing without detriment to critical quality attributes such as titer, binding affinity, stability, and immunogenicity.

48. mRNA-LNP Nucleic Acid Assessment From Distinct Formulations 9/8/2023

    Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.

49. Molecular Weight Confirmation For Length, Integrity And Impurity Analysis Of A 70-Mer Oligonucleotide 9/8/2023

    Explore a workflow used to determine the molecular weight and analyze the purity of a 70-mer DNA sequence with a 3’ dT overhang.

50. Assessment Of Product Quality In Upstream Process Development 9/7/2023

    Simplify your capillary electrophoresis sodium dodecyl sulfate and imaged capillary isoelectric focusing workflows with an automated platform for analyzing protein size and charge during development.