Bioprocessing Application Notes & Case Studies

  1. Expansion Of Human Bone Marrow-Derived MSCs 11/3/2025

    Achieving over 870 million viable, quality mesenchymal stem/stromal cells is possible. This efficient cell culture method scales bone marrow-derived MSCs for clinical needs.

  2. Maximizing MSC Yield And Quality: A Comparative Media Study 11/3/2025

    Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

  3. Overcoming Scale-Up Challenges In Viral Vector TFF 10/29/2025

    Discover how a tailored TFF solution delivers a scalable, high-yield process that integrates smoothly with existing infrastructure and maintains regulatory compliance.

  4. Implementing A Versatile Mixing System To Drive Down Costs 10/29/2025

    Learn how a CDMO reduced capital expenses and operational complexity by adopting an all-in-one mixing solution that supports every stage of production and a wide range of volumes.

  5. Enhancing CRISPR Knock-In And Knock-Out 10/29/2025

    Achieve scalable, non-viral CRISPR delivery for T cells. The next-generation electroporation platform provides robust, efficient gene editing in large-scale volumes.

  6. Cytokines For Ex Vivo Cell Culture 10/29/2025

    Comparable T cell expansion and function between cytokine sources were demonstrated. Generated CAR-T cells showed robust cytotoxicity and lower exhaustion markers.

  7. In Vitro Drug Screening On Cancer Cells 10/29/2025

    Explore a high-throughput assay combining stain-free imaging and multiplexed viability/toxicity measurements to evaluate drug effects on cancer cells, ideal for labs optimizing cell-based screening.

  8. Walk-Away Monitoring Of Cytotoxicity, Viability, And Apoptosis 10/29/2025

    Real-time cell health monitoring reveals how drug dose and timing impact apoptosis, necrosis, and viability. Explore how automated workflows help pinpoint mechanistic toxicity windows.

  9. Getting The Most Out Of Cell-Based Assays With The Optimal Read Function 10/29/2025

    Gain insight into a whole-well fluorescence analysis that improves sensitivity and reproducibility in cell-based assays by accounting for uneven cell distribution.

  10. How Blast Freezing Affects The Quality Of Bottled Drug Substance: Test Results And Insights 10/27/2025

    Uneven ice formation during bottle freezing creates a "Volcano Effect," pushing solutes into highly concentrated zones. This test-based study explains this risk to drug substance quality.