Bioprocessing Application Notes & Case Studies

31. Case Study: ThioBridge™ Conjugates 4/14/2025

    Discover how Abzena’s ThioBridge™ technology is enabling the next generation of stable, scalable, and clinically advanced ADCs through site-specific conjugation.

32. Transfer Of Fed-Batch To Semi-Perfusion Process 4/14/2025

    Continuous processes enhance product quality, yield, and cost savings. Explore transitioning a fed-batch process to perfusion using a small batch bioreactor system to optimize cell culture conditions and comparing performances.

33. Improve Productivity And Reduce Risk With Biostat® RM 4/14/2025

    Discover how a company overcame cell generation challenges by using a system that achieves a seed ratio of 1:120 and saves four days in seed preparation time.

34. Forget About Isolators: Switching From Manual Vial To Automated Bag Filling 4/11/2025

    Discover how transitioning from manual vial filling to single-use bag systems can reduce contamination risk, improve accuracy, and enhance GMP compliance in biopharmaceutical manufacturing.

35. Optimizing TFF And SPTFF For High-Concentration mAb Formulations 4/9/2025

    Discover the critical role of formulation buffer composition in stabilizing monoclonal antibodies during tangential flow filtration, a process involving ultrafiltration and diafiltration under high pressure and shear forces.

36. Selecting A Platform Filter For High Concentration mAbs 4/9/2025

    Read more about how Fujifilm Diosynth Biotechnologies evaluated a prime filter with challenging simulant solutions and how the experimental data confirmed superior performance, which demonstrated twice the throughput.

37. Innovative Therapeutic Applications Of Ion Exchange Resins 4/8/2025

    Chromatography resins are aiding in the delivery of cancer and inflammatory disease therapies. Learn how ion exchange resins act as therapeutic carriers for advanced drug delivery.

38. A Novel Approach To Improving AAV Titers 4/8/2025

    As demand for AAV-based therapies rises, optimizing production processes is essential. By utilizing existing technologies, tailored platforms, and optimized formulations, titers and productivity can be enhanced.

39. A Dilute-And-Shoot Method For Monitoring mAb PQAs From Spent Media 4/8/2025

    Learn more about an assay that innovatively measures monoclonal antibody PQAs directly from cell culture media and offers comprehensive insights into charge and glycoform heterogeneity to simplify upstream bioprocessing.

40. A Study To Assess Organoid Size And Cell Count From 3D Image Analysis 4/4/2025

    Recent advancements in 3D patient-derived organoids (PDOs) offer improved predictive power over traditional 2D assays. Explore a patented bioprocess for PDO expansion that could revolutionize drug discovery, especially in oncology.