Bioprocessing Application Notes & Case Studies

31. Accelerating The Development And Optimization Of Cell Culture Media 10/18/2024

    Here, we outline the use of a microbioreactor for the rapid screening and optimization of media formulations for perfusion processes, and its role in predicting the performance of larger-scale bioreactors.

32. Enhancing Process And QC For Multi-Column Chromatography 10/16/2024

    Explore two innovative technologies that address major purification challenges in DSP: continuous multi-column chromatography and advanced chromatography or liquid chromatography-mass spectrometry.

33. Vaporized Hydrogen Peroxide (VHP) Resistance Testing 10/16/2024

    Explore test results demonstrating the suitability of a robust microbial sampler for environments where frequent exposure to harsh cleaning and sterilization methods, like VHP in isolators, is routine.

34. Mixing Of Various Dry Powdered Media And Buffers 10/16/2024

    Explore how this mixing system efficiently handles various powdered media and buffers, ensuring precise solubilization and mixing in applications like cell culture and protein purification.

35. Super Short Activated CAR-T Process 10/16/2024

    Experience the benefits of faster, more effective CAR-T cell production with this innovative three-day short-cycle process, designed to enhance patient treatment outcomes while reducing costs.

36. Resolute® BioSC Pilot: Designed For Effective And Consistent Chemical And Microbiological Cleaning 10/10/2024

    Issues related to cleaning and cleaning validation are some of the most common concerns that arise in FDA Warning Letters. Discover how to ensure you pass your cleaning validation tests.

37. Achieving Optimal CAR-T Cell Generation 10/9/2024

    Discover the innovative methods behind CAR-T cell production, from custom plasmid design to lentiviral vector transduction, and explore their potential in revolutionizing cancer treatment.

38. Integrated Services For Cell Line Preparation And Storage 10/8/2024

    Explore a comprehensive suite of services for the manufacture, characterization, and storage of cell banks as well as the advantages of working with an experienced partner.

39. Get Reproducible Purification Scale-Up Results Faster 10/8/2024

    Is it difficult to reproduce laboratory purification results at process scale? We evaluated three prepacked columns from 1.6 to 33 cm column inner diameter (ID) with 20 cm bed height to observe their purification profiles.

40. Alternative Two-Step Mixed-Mode Approach To A mAb Purification Process 10/8/2024

    Two post–Protein A capture two-step mAb processes were developed and compared to an archetypical three-step mAb purification process using two IEX steps after Protein A capture.