Bioprocessing Application Notes & Case Studies

31. Pharmacokinetic Study Of Salbutamol Through Nose Only Exposure In CD-1 Male Mice 5/13/2025

    Explore how using advanced tools like the inExpose system can provide precise measurements of lung and plasma drug concentrations to optimize inhalation therapy for pulmonary treatments.

32. A Duplex Assay For Quantification And Qualification Of AAV 5/13/2025

    Adeno-associated virus is a key gene therapy vector. Explore how digital PCR offers precise, standard-free quantification with improved consistency and inhibitor tolerance over traditional qPCR methods.

33. Analysis Of DNA Integrity And Stability Using Digital PCR 5/13/2025

    Digital PCR offers precise, inhibitor-resistant DNA quantification and genome integrity assessment. Discover how this method enhances accuracy and reproducibility, especially in AAV analysis, using multiplexed targets and Poisson-based calculations.

34. PSC Perfusion Guidance Using Vertical-Wheel Bioreactors 5/9/2025

    Unlock the potential of perfusion for pluripotent stem cell cultures. Explore key insights into achieving improved consistency and quality in your medium exchange protocols, leading to better outcomes.

35. The Role Of Peptones In Boosting Monoclonal Antibody Production 5/9/2025

    Peptones have become a key tool in CHO cell bioprocessing, enhancing monoclonal antibody yield and quality.

36. A Paperless Lab Simplifies, Accelerates Full Sample Lifecycle Data Management 5/1/2025

    Implementing IDBS’ ELN helped Crown Bioscience realize electronic experimental records, optimizing our business processes and helping them to be more standardized.

37. Stability Screening For Colloidal Stability: Diffusion Interaction Parameter Thermal Shift Assay 4/28/2025

    Colloidal stability is one of the most important properties to control due to the propensity for biopharmaceuticals to aggregate and the subsequent potential to severely affect the drug's efficacy and patient safety.

38. Why Cell Line Screening Is Crucial For Successful CDC Assay Development 4/28/2025

    In developing a CDC assay for therapeutic mAb characterization or QC release testing, in addition to selecting a target cell line that expresses the mAb ligand, consideration should be made to the expression of CRPs on the cell surface.

39. Demonstration Of Scalability For A Novel Fixed Bed Reactor Platform 4/28/2025

    Designed to enable efficient scalability, a new FBR platform allows operators to use one technology, with a standardized workflow, for their process development, scale-up, and manufacturing processes.

40. CDMO Uses Robotic Gloveless Isolator For Advanced Therapeutics 4/28/2025

    CDMOs must innovate production architectures to meet the demands of advanced therapeutics to ensure a reliable supply and compliance. Discover how these approaches advance modern medicine and improve patient outcomes.