Bioprocess Online for bioanalytics, biopurification, bioproduction

AI Is Not The CMC Revolution You're Looking For, And That's OK

Advanced therapy development today is less about big funding, more about frugality. Artificial intelligence unlocks a competitive advantage.

More Featured Editorial

EDITOR'S DESK

On The Ground At BPI: Kat Kozyrytska On Ethical AI And Collaboration
AI consultant Kat Kozyrytska advocates for ethical AI adoption and explains its potential to foster collaboration across the industry.

On The Ground At BPI: Takeda's Amy Shaw On Scaling Cell Therapy Manufacturing

Takeda head of process development, Amy Shaw, explains what factors to consider when scaling up or scaling out cell therapy manufacturing.

On The Ground At BPI: Industry Reflections With Carl Schoellhammer, Ph.D.

DeciBio partner Carl Schoellhammer, Ph.D., speaks on the record with Bioprocess Online's chief editor Tyler Menichiello at the 2025 BioProcess International conference in Boston.

The Death Of A Dogma: David Baltimore And Lessons For Modern Drug Discovery

Nobel laureate, David Baltimore passed away at 87 years old, on September 6, 2025. He was widely regarded as a scientific visionary who at just 37, co-discovered reverse transcriptase, an enzyme that flipped molecular biology on its head by showing that genetic information could flow from RNA back to DNA, not just the other way around.

Single-Use Standardization Starts At Home

During a Bioprocess Online Live event, “Single-Use Harmonization Needs A Tune Up," panelists discuss a way forward for the industry to unlock the true flexibility and promise of single-use technology.

GUEST COLUMNISTS

Solving The Stem Cell Consistency Conundrum With iMSCs
The ability to produce unlimited batches of induced mesenchymal stem cells from a single iPSC cell bank is, perhaps, one of their most alluring features.
Sensitive Critical Starting Materials Need A 'Just-In-Data' Approach
Here's a blueprint for transforming the fragmented, high-risk interface between vector and cell therapy platforms into a unified, predictable, and compliant system.
Exploring The Benefits Of Electroporation In NK Cell Transfection
Electroporation creates temporary holes in cell membranes for genetic material to slip through. The technique offers some key advantages to viral transduction.
On The Potency Assurance Journey, Travelers Need A Road Map
When regulatory expectations change by the phase, the route can be difficult and confusing to navigate for both new and experienced potency investigators.
It's Not Just You, Everyone's Talking About OPV
Ongoing process verification has evolved beyond a compliance exercise to a strategic priority thanks, in part, to technology advancements.
Guidelines For Defining A Control Strategy Framework For Accelerated mAb Programs
This article assembles an industrywide “platform” knowledge base on the impact of parameters across unit operations in a standard mAb process.
A Multi-Omics Approach For Characterizing Clinical-Scale iPSC Batches
The transition from 2D to 3D cell culture requires a combination of advanced analytical techniques, but aligning new methods with established principles can be challenging.
Global Implications Of Zero Tariffs On Indian Pharma Exports To China
Discover the worldwide impacts of China’s zero-tariff policy on Indian pharmaceutical drugs.

BIOPROCESSING WHITE PAPERS

A Checklist For Efficient And Reliable Gene Therapy Manufacturing
Gain insight into how to design and execute an efficient upstream AAV production process, and follow the checklist within to ensure all appropriate factors are considered at each phase of drug development.

Business Continuity Management: The Benzonase® Endonuclease Success Story
8/21/2024

Business continuity management is a key success contributor to the pharma industry. Explore best practices for a robust supply chain and how they can translate into success stories.
Designing, Selecting, And Developing Bioconjugates For Clinical Success
10/24/2024

Accelerate the development of complex bioconjugates to unlock new possibilities for targeted therapies and advance the next generation of precision medicine.
Application Of Plant And Process Models
1/22/2025

Explore innovative process and facility models that optimize efficiency, sustainability, and cost-effectiveness in biopharmaceutical manufacturing.
Elevating mRNA Manufacturing Toward GMP-Readiness
8/27/2025

The mRNA Technology Transfer Program empowers LMICs with scalable vaccine production. Learn about a partnership that drives innovation in mRNA and sets a global blueprint for equitable health access.
Optimizing Poloxamer 188
1/13/2025

Poloxamer 188 stabilizes proteins in liquid formulations and protects cells from shear stress. Molecular weight and hydrophobicity variations influence its effectiveness in different biopharmaceutical applications.

More Bioprocessing White Papers

BIOPROCESSING APP NOTES & CASE STUDIES

More Bioprocessing App Notes & Case Studies

BIOPROCESS ONLINE CONTENT COLLECTIONS

This collection of articles digs into the industry’s growing focus on knowledge management as an indispensable facet of biomanufacturing and pharmaceutical development, exploring how it plays into risk management, quality, vendor relationships, and supply chain resilience.