Insights On Upstream Manufacturing

  1. Expansion Of Human Bone Marrow-Derived MSCs 11/3/2025

    Achieving over 870 million viable, quality mesenchymal stem/stromal cells is possible. This efficient cell culture method scales bone marrow-derived MSCs for clinical needs.

  2. Maximizing MSC Yield And Quality: A Comparative Media Study 11/3/2025

    Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

  3. Comparing Advanced Cell Culture Vessels vs. Traditional Options 10/31/2025

    Learn how innovative cell culture vessel design enables high-density cell growth with superior gas exchange and a closed system to scale up bioproduction efficiently while maintaining batch-to-batch consistency.

  4. Implementing A Versatile Mixing System To Drive Down Costs 10/29/2025

    Learn how a CDMO reduced capital expenses and operational complexity by adopting an all-in-one mixing solution that supports every stage of production and a wide range of volumes.

  5. The Case For Optimized And Excipient GMP Cell Culture Solutions 10/27/2025

    Learn how optimized, customizable formulations and Excipient GMP manufacturing streamline development, ensuring quality and consistency for a de-risked path to the clinic.

  6. A Simple And Accurate Method To Quantify Molar Concentrations 10/24/2025

    Explore a fast, size-independent method for NGS library quantification that improves accuracy, reduces workflow time, and ensures consistent sequencing results without the need for qPCR.

  7. Advance Long-Term Cell Kinetics With Integrated Fluid Handling 10/24/2025

    Examine how a novel setup enables uninterrupted long-term cell-based assays by combining CO₂ regulation and evaporation control to improve cell viability and data consistency for real-time analysis.

  8. Smarter CMC Strategies To Accelerate Next-Gen Biologics To The Clinic 10/23/2025

    Learn how process design and cross-functional collaboration mitigate risks and accelerate the path from early development to FIH manufacturing through real-world case studies of practical approaches.

  9. Cell Culture Media Filtration: Evaluating Cell Culture Performance 10/23/2025

    Cell culture performance remained consistent across PES and PVDF filters, even under worst-case filtration conditions. Discover a practical framework for evaluating membrane impact on CHO cell growth.

  10. Enhancing Non-Viral CAR T Manufacturing With Electroporation And Microbubble T Cell Isolation 10/22/2025

    Unlock superior non-viral CAR T manufacturing outcomes by combining gentle microbubble T cell isolation with advanced electroporation. See how this approach boosts cell viability and transfection efficiency.