Insights On Upstream Manufacturing

  1. Best Practices For Scaling PSC Expansion From Bench To Pilot To Commercial Scale 6/19/2025

    Achieve reproducible and robust PSC expansion with proven best practices. This session covers single-cell passaging, perfusion feeding, and in-vessel harvesting to streamline your process for efficient, linear scale-up.

  2. Quicker Development Using Cell Line Integration, End-To-End Support 6/19/2025

    Despite challenges with mammalian host cell line diversity, Lonza's mitigation strategies drive efficiency and reproducibility, maximizing cell growth and product quality.

  3. Guide To Seeding, Expanding, And Harvesting Stem Cells 6/18/2025

    Investigate important considerations for working with three different stem cell types: mesenchymal stem/stromal cells, induced pluripotent stem cells, and neural stem cells.

  4. Perfusion: Medium Selection And Testing 6/16/2025

    An examination of what to consider in a perfusion medium, including varying reconstituted concentrations, supporting multiple cell clones, allowing for high cell densities at low medium exchange rates, and using it in various types of perfusion.

  5. The Value Of Peptones For Cost-Effective Vaccine Manufacturing 6/16/2025

    Peptones offer a strategic solution to key biomanufacturing challenges by enhancing cell culture performance, improving yields, and reducing production costs.

  6. Development Of A CHO Medium And Feed System Using Advanced Analytical Tools And Workflow Considerations 6/16/2025

    Discover how a new, chemically defined cell culture medium and feed system can maximize recombinant protein production in Chinese hamster ovary (CHO) cells, enhancing productivity and streamlining manufacturing.

  7. Manufacturing CAR T Cell Therapies: Challenges, Insights And Solutions 6/16/2025

    Manufacturing patient-specific cell therapies is a complex, multi-step process. Addressing key hurdles in production time, scalability, and cost is crucial to making these vital treatments more accessible.

  8. Next-Gen Biomanufacturing: Process Intensification For mAb Production 6/13/2025

    Intensified processes, omics-driven media, and advanced bioreactors can boost efficiency and scalability in mAb production.

  9. Deliver What's Next With A Cell Therapy Manufacturing Platform 6/11/2025

    Streamline CAR T cell therapy manufacturing with an end-to-end solution featuring two automated systems that optimize every stage from cell isolation to final therapeutic dose.

  10. Improved T Cell Expansion Using Closed, Automated Stirred-Tank Bioreactors 6/10/2025

    A shift from traditional rocking motion systems to stirred-tank bioreactors can enhance T cell expansion, offering greater scalability and more intimate process control.