Bioprocessing Application Notes & Case Studies

  1. AOC GMP Manufacture For A FIH Study 6/9/2026

    See an outline antibody-oligonucleotide conjugate manufacturing: process development, scale-up, GMP production, and analytical controls for efficient early-phase clinical material generation

  2. Improve Process Control And Achieve More Consistent Outcomes 6/4/2026

    Mixing efficiency at scale depends on more than speed alone. Gain insight into data that reveals how fill levels and vortex formation impact homogenization time, offering practical guidance.

  3. Lead Identification And Optimization For Computational Drug Discovery 6/3/2026

    AI-generated Fab molecules promise speed, but can computational designs actually express and bind at scale? A high-throughput screening workflow offers a data-backed answer.

  4. Fast-Tracking NDA Approval For A Novel Compound To Treat Infections 6/2/2026

    Strategic tech transfer and scalable manufacturing enabled rapid NDA approval, delivering registration batches and accelerating commercialization of a novel therapy for drug-resistant infections.

  5. Mammalian Expression 5/28/2026

    See how a biotechnology company advanced an engineered protein therapeutic while navigating development, regulatory, and scalability challenges. 

  6. Get Up To 4X Titer With N-1 Perfusion 5/26/2026

    N-1 perfusion improves antibody production by increasing cell density, optimizing media and conditions, boosting yields up to 4.5× while maintaining quality and reducing manufacturing time and costs.

  7. Evaluating Antibody Fragment Purification Using VH3 Resin 5/22/2026

    Explore how VH-domain targeting enables efficient purification of VH3 antibody fragments and bispecific formats, with strong recoveries and flexible wash conditions that support improved purity.

  8. Mild pH Protein A Purification Step With A Mild Elution Resin 5/22/2026

    As antibody formats diversify, low-pH protein A elution can drive aggregation and yield loss. Learn how milder elution conditions during capture can help protect sensitive molecules and ease challenges.

  9. Controlling mAb Aggregates In Chromatography Process Development 5/22/2026

    Antibody aggregation remains a critical downstream challenge, particularly for complex modalities. Explore why aggregates form, why they matter, and how chromatographic strategies can help reduce risk.

  10. How Automated ADC Filling Cuts Labor By 90% 5/20/2026

    Manual ADC filling demands 30 labor hours per batch, introduces contamination risk, and leaves product recovery to chance.See how automation cut that to 2 hours with ROI in under a year.