Bioprocessing Application Notes & Case Studies
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Using Automated Spinoculation For CAR T Cell Lentiviral Transduction
2/26/2024
There is a growing demand for closed and automated lentiviral transduction steps in CAR T cell therapy workflows. Learn about a potential solution to address this unmet need.
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A New Way To Perform mAb Capture
2/21/2024
Combining high-productivity chromatography methods and SU affinity membranes delivers a viable alternative to the current packed bed Protein A capture techniques for intensified purification of mAbs.
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Re-Imagining Chromatography: Building Efficient Downstream Processes
2/21/2024
Explore a stepwise approach for integrating process intensification principles into an existing process to increase productivity, reduce costs, and improve process sustainability.
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Integrated And Connected Downstream Processing Of mAbs
2/21/2024
We describe how intensifying two chromatography polishing steps by developing unit operations using Sartobind® Q and CMM HyperCel saves buffer volumes and accelerates the downstream process.
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Alofisel P3 Cell Therapy Facility
2/21/2024
Despite various issues with a client's CQV project, CAI delivered the project on time and significantly contributed to the delivery of the first ATMP facility in Ireland.
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EMPQ And Validation Support Services
2/21/2024
A growing pharmaceutical/biotech company hired a global consulting firm for a project that required EMPQ services for qualification activities on a newly completed aseptic processing suite.
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The Use Of Injectable Packaging From Early Development To Commercialization
2/20/2024
While in their early-stage development of a mAb biosimilar for oncology treatment, a large biopharmaceuticals company sought a packaging recommendation: a stopper to maintain high-quality standards.
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Optimizing Process Loads For VHP Decontamination
2/20/2024
Explore how CAI helped a company rescue a failing CQV project and create more efficient Vaporized Hydrogen Peroxide Material Air Lock (VHP MAL) Loads to enhance operational efficiency.
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SAP S4HANA Implementation: Commissioning, Qualification, And Validation
2/20/2024
Explore how CAI helped one company navigate complications when implementing SAP and how new solutions are being developed, validated, and implemented to establish this new global ERP system.
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Lentiviral Vector Bioproduction Follow-Up Tool
2/12/2024
Explore a new optical device that performs real-time, user-friendly, and label-free measurements of lentiviral vector physical titer and size distribution.