ABOUT SINGLE USE SUPPORT

Single Use Support is a solution provider of innovative single use technologies for logistics and cold chain processes. At Single Use Support, we have set ourselves the goal to provide the biopharmaceutical industry with solutions that support them in increasing the reliability of storage and shipping and in turn minimizing the loss of valuable high-quality drug substance. On the basis of single use bags, Single Use Support offers biopharma companies access to a new and 100% secure logistics process for liquids.

The innovative process solution provider enables its customers to set up highly robust bulk drug substance freeze/transportation/storage processes for single-use bags, which in turn in creases patient safety and reduces the risk of bio-contamination and product loss. With the utilization of Single Use Support technology, bigger volumes of high-quality substance can be shipped internationally in a faster and absolutely secure manner, and at a lower loading volume.

Single Use Support was founded in 2016 and is based in Kufstein, Austria. At the global headquarters, new products are developed in cooperation with international pharmaceutical companies.

In the past years, Single Use Support GmbH has developed technologies that bridge the gap in handling of biopharmaceuticals. Its entire end-to-end process for biopharma liquid logistics are applicable to various areas, such as bulk drug substance, cell & gene therapies and seed train intensification. The core product RoSS, a single use bag protective shell system developed by Single Use Support, provides the basis for technologies and services around filling, freezing, shipping, storing, thawing and draining regardless of the biopharmaceutical product and the primary packaging used.

FEATURED PRODUCTS

Fully automated filling & draining system of multiple small single use bags in cell & gene therapies at highest accuracy.

RoSS.PADL is a scalable platform for cooling your single-use bag whilst gently massaging it to ensure there is a homogenous mixture of the solution. With the RoSS.PADL multiple cooling and massaging mechanisms can be placed side by side with one control system.

RoSS.LIQU is a smart rigid tote to protect 3D single-use bags with large volumes of up to 1000L for shipping applications. This robust stainless steel transport container is re-usable and offers a sustainable solution for single-use bag shipments compared to plastic alternatives.

Scale-down to one single drop of drug substance! RoSS.KSET offers the protection for drug substances between 1 ml to 250 ml. For anything above, RoSS can protect one or multiple small single use bags in one shell.

RoSS.FILL is a flexible platform for dispensing operations into single use bags and bottles and for bulk filtration. The fluid path is designed to be fully disposable and is able to accommodate a variety of sterile connection and disconnection options.

Refrigerating frozen drug substances for storage. Flexible, Stackable, Mobile, Coolable & Scalable.

Frozen liquids need to be transported from A to B... we enable it!

NEXT Generation Cell Culture Intensification: Taking the shortcut in biopharma upstream manufacturing process!

RoSS is an absolutely safe and tamper evident protective tray for 2D single use bags. It is compact and easy to handle during storage and shipping. The shell consists of the perfect combination of different materials that protect the bag from external impact.

RoSS.pFTU is a flexible plate-based freeze-thaw unit for any scale and batch sizes. The platform is compatible with single use bags and also bottles of all manufacturers and sizes. RoSS.pFTU is the perfect solution if you are looking for a monitored and scalable freezing process. Our RoSS freeze/thaw units allow for the quickest possible freezing and thawing of drug substances. The platforms not only facilitate quick but also constant freezing and thawing of high-quality liquids with the advantage of maintaining the liquid’s quality and consistency throughout the process.

100% secure integrity test for single use bags – "at point-of-use" and across all manufacturers.

Highly robust, stackable, coolable and compact – Fort Knox for high-quality substances!

Stainless steel trolley for up to 22 RoSS® trays for handling and storage. Simply ask for details.

The RoSS.FILL Flex Rack enables you to now also fill bottles with your RoSS.FILL, making the transition from bottles to single use bags easy.

CONTACT INFORMATION

Single Use Support

Endach 36

Kufstein, 6330

AUSTRIA

Contact: Thomas Wurm

FEATURED ARTICLES

  • Read how the implementation of Pharma 4.0 standards and SOPs aims to reduce the different types of human error through the automation of processes that have traditionally involved human performance.

  • These insights provide a brief primer on Pharma 4.0 and will convey the key principles of the digital revolution in the pharma sector.

  • This article will give an overview of the inline buffer dilution process and discuss its benefits compared to traditional formulation of buffer solutions.

  • Today's challenges require a move towards agility and change, especially in the biopharma industry. Old-established structures will need to be reconsidered or even restablished and renewed.

  • Controlling the freezing behavior of bulk drug substance is the ultimate goal in biopharma manufacturing. This study demonstrates the impact of ice front growth speed on scalability of freezing protein solutions.

  • Supply chain management for CGTs will become increasingly complex to sustain their specific requirements. A much-needed approach to solving problems related to supply chain management is the development of smart packaging and related smart technologies.

  • When it comes to saving a patient’s life, speed and safety are key – as is the safe handling of the matter, where special protective and coolable packaging play a crucial role.

  • There is no full Pharma 4.0 manufacturing in place yet, but there are first innovations to build on.

  • Cell and gene therapies yield a small volume of individualized product for each single patient. Loss of the shipment or damage to the transported goods have serious consequences for patients.

  • There is still potential product loss with unprotected single-use bags, and there are still human errors dampening the euphoria of single-use systems. Here's how to protect your product investment.

  • The supply chain of single-use assemblies is presently the biggest bottleneck in biopharmaceutical manufacturing. Single Use Support GmbH is taking quick action to alleviate this industry-wide pain by offering single-use manifold assemblies, and – starting today – launching its new online configurator MyManifold.com.

  • RoSS shells contain 3D foams to protect and immobilize the filled and frozen bags while transporting. In this study we tested the RoSS shell's influence on the sterility on ISO cleanrooms

  • Until recently, only isolated solutions for working filling, freezing/thawing and transporting sensitive drug materials were available. Learn how we've addressed this problem with end-to-end bottle solutions.

  • Plastic totes to carry large 3D single-use bags are widely spread across the biopharma environment. However, they sometimes fail to withstand volumes of biopharmaceuticals up to 1000L.

  • Many of the countless biopharma freezers don’t meet the requirements of big pharma or small biotech. This comparison of cold storage options will help you make sound decisions for ultracold storage. 

  • Decontamination by vaporized hydrogen peroxide is common in the pharmaceutical industry. Here, we examine the resistance of RoSS and Bottle RoSS and components against 3% hydrogen peroxide.

  • The Indianapolis-based CDMO has ordered RoSS.FILL CGT to fill lentiviral vectors into small single-use bags. Specially designed for cell and gene therapies, RoSS.FILL CGT is an automated cGMP-compliant filling and filtration platform to dispense small to medium sized volumes of highly valuable drug substances into multiple small single use bags. The technology will be supplied to Genezen’s facility by the end of 2021.

  • Scalability around freezing means the ability to guarantee constant stress on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. Read how by standardizing the IFGS – icefront growth speed – for all possible scenarios regardless of the filling volume and type of bags but also regardless of the type of system, i.e. whether LabScale, MidScale or LargeScale, you can fulil this requirement.

  • Less than 0,01% of the plastic waste generated annually worldwide are single-use technologies derived from the biopharma. This portion is subject to strict guidelines, so they’re usually collected, decontaminated and disposed rigorously. Furthermore, manufacturers of single-use technologies are obliged to facilitate the separation of the product into its base materials after use. Therefore, the single-use products are mostly very easy to recycle.

  • The international provider of process solutions for the biopharmaceutical industry, Single Use Support, which was only founded in 2016, is experiencing a massive run on its product innovations.

VIDEOS