Decontamination by means of vaporized hydrogen peroxide is commonly used within the pharmaceutical industry. The goal is to keep the bioburden as reduced in microorganisms as possible when handling with bio-decontamination agents. H2O2 – or vaporized hydrogen peroxide disinfects such agents. While being non-toxic, it destroys biological contaminants. In this study, we examine the the resistance of RoSS and Bottle RoSS with its different components against 3% hydrogen peroxide.

The Indianapolis-based CDMO has ordered RoSS.FILL CGT to fill lentiviral vectors into small single-use bags. Specially designed for cell and gene therapies, RoSS.FILL CGT is an automated cGMP-compliant filling and filtration platform to dispense small to medium sized volumes of highly valuable drug substances into multiple small single use bags. The technology will be supplied to Genezen’s facility by the end of 2021.

Scalability around freezing means the ability to guarantee constant stress on proteins (biopharmaceutical molecules) in all scales, filling volumes and loading scenarios. Read how by standardizing the IFGS – icefront growth speed – for all possible scenarios regardless of the filling volume and type of bags but also regardless of the type of system, i.e. whether LabScale, MidScale or LargeScale, you can fulil this requirement.

Less than 0,01% of the plastic waste generated annually worldwide are single-use technologies derived from the biopharma. This portion is subject to strict guidelines, so they’re usually collected, decontaminated and disposed rigorously. Furthermore, manufacturers of single-use technologies are obliged to facilitate the separation of the product into its base materials after use. Therefore, the single-use products are mostly very easy to recycle.

The international provider of process solutions for the biopharmaceutical industry, Single Use Support, which was only founded in 2016, is experiencing a massive run on its product innovations.

In an extremely complex, competitive and constantly evolving sector such as the biopharmaceutical industry, flexibility is key, not least since it is an immensely varied and compliance-driven field. This is one of the reasons why more and more logistics solutions – covering all steps from filling to freezing, thawing and distribution – are primarily based on single-use technologies. Read more on you can optimize performance and efficiency with single-use technologies.

Single-use components might not be considered as the most essential parts in biopharmaceutical manufacturing. However, they are quite capable of temporarily paralyzing the entire production of biopharmaceuticals on-site. Manufacturers need to fuel up the pace as supplies are scarce or being stockpiled in the era of COVID-19 vaccine production levels.

Single Use Support wanted to take a closer look into the single use bags when they’re at frozen state. The aim was to visually compare the interfacial stress of frozen single use bags: How does the bag experience stress in two different approaches of freezing, plate-based freezers and conventional static freezers?

SUSupport is a leading provider of safe, reliable and user-friendly solutions when it comes to protected storage and/or shipping of highly sensitive and at the same time highly valuable drug substance contained in single use bags. In addition to their flagship product, the RoSS shell, which protects 2D single-use bags of various sizes, the Austrian solution provider has now developed a stainless-steel 3D bag holder that offers reliable protection for all single use bags of up to 1,000 l.

In order to comply with the versatile requirements of today’s market, flexibility and the option to customize are key whilst maintaining availability and short lead times. This is true for many areas, not least when it comes to the ever-growing number of single-use technologies utilized in the biopharmaceutical industry.

To comply with the versatile requirements of today’s market, flexibility and the option to customize are key whilst maintaining availability and short lead times.

There are many choices for freezing biopharmaceutical bulk material. This paper demonstrates that the initial price can be deceiving and the significant additional costs during ongoing usage. 

CAR-T cell therapy is a promising personalized approach in the treatment of acute or chronic leukemia. Find out more about the CAR therapy and its related chances and risks in this article.

In response to the changing process intensification, development, and production requirements, more labs are choosing an approach based on recyclable and extremely flexible single-use technologies

How biopharma companies are leveraging the speed and flexibility enabled by single use technologies and systems to navigate the maze to a vaccine against COVID-19.

One of the most renowned biopharmaceutical companies in India orders the complete product range of the start-up company Single Use Support based in Austria. The large order associated with this not only opens up the emerging Indian biopharma market, but also underlines the growing relevance of holistic process solutions.

Regardless of all potential pitfalls from the current pandemic Single Use Support has reached the next milestone in its thriving development: The large scale freeze/thaw platform has been commissioned on site in California/US virtually.

Thanks to a cooperation with BakerHicks, Single Use Support is now taking the qualification and validation strategies of mechatronic systems to the next level.

While technically simple to perform, the freeze-storage-thaw cycle comprises several mechanistic aspects that can compromise protein quality if not properly understood and addressed.

There are currently many options of primary packages on how to transport the drug substance from A to B. This paper explains the benefits and shortcomings of a few of those options.

Flexibility - How to prevent being stuck in one single-use system for biopharmaceuticals.

Liquid bulk drug substance is of utmost value after manufacturing from Biopharma industries. The single use bag independent platform RoSS helps to avoid product loss through breakages through robust composition and makes it possible to introduce your flexible end-to-end solution in drug substance logistics.

Our unrivaled lead times while adjusting to your specifications make it easy to get your customized manifold for filling of drug substance into single use bags and bottles.

We close the gap between downstream and the fill & finish process in the biopharma industry. On the basis of single-use bags, we offer biopharma companies access to a new and almost 100% secure logistics process for liquids.

For any single use bag and any freezing infrastructure freeze your drug substance/product without worries! The right material at the right place – what we can learn from oysters. Tough protected & tamper evident! The tried and tested single-use bag gets its 100% secure and compact shell.

RoSS.pFTU is our “standard" freeze-thaw platform. It is suitable for different batch sizes and offers a fully scalable solution for medium-sized and large batch volumes. The platform is the perfect freeze & thaw single use option as it is compatible with single use bags from all established manufacturers as well as with different sizes and volumes.