5 Overlooked Challenges In Viral Vector Manufacturing

Viral vector play a vital role in gene therapy and research, carrying genetic materials and transporting them into target cells. Most common viral vectors used in gene therapies are adeno-associated virus (AAV), lentivirus (LV), adenovirus (AVV), retrovirus (RV), and herpes simplex virus. This guide explores the use of viral vectors in gene therapies, as well as fluid management and other factors that negatively effect viral vectors during manufacturing.

We will cover:

• Scalability in Cell Line Development
• Accuracy in Bag Aliquoting
• Viscosity and Homogeneity in Liquid Transfer
• Product Viability after Freezing & Thawing
• and Bag Breakages in viral vector storage and shipping