DOWNSTREAM PROCESSING FEATURED ARTICLES
Sanford-Burnham Research Projects Selected To Go To Space
We’re excited to announce recently that two of our research teams have won Space Florida’sInternational Space Station (ISS) Research Competition. Eight teams were selected from a pool of international applicants to send experiments to space in late 2013.
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![SterileConnectors]( "High-Flow Sterile Connectors For Single-Use Applications")
High-Flow Sterile Connectors For Single-Use ApplicationsOver the past decade, two developments have increased demand for high fl ow-rate connectors: Size advances in single-use bioreactors up to 2000L and the implementation of single-use downstream.
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![PhenomemexTabless-Tube-Hold]( "New SPE Accessories Hold Tubes In 96-Well Spacing For Automated Applications")
New SPE Accessories Hold Tubes In 96-Well Spacing For Automated ApplicationsPhenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces two new Tabless Tube Holder accessories for its Strata and Strata-X lines of silica-based and polymeric solid phase extraction (SPE) sorbents.
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Stratagene Introduces A New Product For Human Splice Variant Discovery Stratagene Corporation, a developer, manufacturer and marketer of specialized life science research and diagnostic products, announced the commercial availability of the Human SpliceMiner cDNA Library Panel
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Efficiencies Of Natural Convection In Passive Pallet Shippers
Bulk transportation of temperature sensitive pharmaceuticals and biologics has become a common practice due to complex global supply chains. By Iftekhar Ahmed, Ben VanderPlas, and Stu Krupnick
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![Bio-rad]( "Improving Aggregate Removal From mAb Feed Using Cation Exchange Chromatography")
Improving Aggregate Removal From mAb Feed Using Cation Exchange ChromatographyResearchers in the field of chromatography have required ever more sophisticated and selective methods for removing aggregates from the monomer.
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Automated Bioluminescent ADCC Reporter Bioassay Using Bioengineered Jurkat Cells
Pharmaceutical companies are increasingly exploring new biologic and biosimilar products, and thus increasing monoclonal antibody (mAb) immunotherapeutic research. By Tracy Worzella, Promega Corporation and Brad Larson, Applications Department, BioTek Instruments, Inc.
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Sani-Tech® Ultra White Paper
For several years, pharmaceutical manufacturing professionals have increasingly stated concerns about material leachables and extractables and their impact on the products they produce. Fluid transfer systems that include flexible tubing have been at the forefront of this discussion.
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![Test tubes laboratory GettyImages-1310126023]( "Examining Column Reproducibility During Method Development In Clinical Labs")
Examining Column Reproducibility During Method Development In Clinical LabsIn this study demonstrates how the HSS T3 stationary phase is a reliable stationary phase, as three batches made over a five-year span provide comparable results.
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Guidelines For Proper Filtration And Delivery Of Samples To On-Line Process Analyzers
Increasingly precise process control strategies, often linked to computer control, have accelerated the use of sophisticated on-line chemical composition analyzers in plant applications. Instruments such as gas and liquid chromatographs, ion chromatographs, laser optic instruments, atomic absorption instruments and specific ion analyzers, which were rarities in laboratories ten years ago, are now found routinely in plant settings. By Ken Perrotta, Division Engineering Manager
DOWNSTREAM PROCESSING PRODUCTS
Bio-Beads SM-2 nonpolar polystyrene adsorbents are analytical grade, neutral macroporous polymeric beads for use in hydrophobic interaction chromatography.
Resin are designed specifically for intermediate purification steps that remove host-cell contaminants from partially purified targets using strong or weak hydrophobic interactions. Methacrylate-based beads for protein and nucleic acid purification using hydrophobic interactions are available for purifying compounds that have weak or strong hydrophobic regions.
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.