DOWNSTREAM PROCESSING FEATURED ARTICLES

Frost & Sullivan Lauds Pfenex Inc. For Developing A Protein Expression Platform That Delivers Unparalleled Success And Speed

Based on its comprehensive  TEAM Research rigorous 10 step evaluation methodology, Frost & Sullivan has awarded Pfenex Inc. with the 2012 North American Enabling Technology Award in Microbial Expression Technology.

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DOWNSTREAM PROCESSING PRODUCTS

DNA methylation events are heritable modifications that regulate gene expression without altering the DNA sequence itself. They serve as regulatory mechanisms for a wide range of biological processes and genetic diseases, and irregular methylation patterns have been associated with certain cancers.

Choose from ten fixed volume SoftGrip pipettes covering 0.2 µL to 1 mL. All pipettes have color-coded plunger buttons and labels for easy volume identification.

The CESI 8000 High Performance Separation-ESI Module is designed for mass spectrometry applications that analyze charged and polar molecules. Thanks to its robust OptiMS technology, the advantages of Capillary Electrophoresis are now delivered to the mass spectrometer without dilution or disturbance.

The Avanti® J-HC High Capacity Centrifuge provides you with a complete solution for batch bioprocessing. A maximum of 9 Liters can be spun at speeds of 5,000 rpm and 7,480 x g for greater sample throughput. This allows processing of up to 36 Liters per hour when harvesting bacteria. Enhanced operator safety is provided with disposable HarvestLine System Liners.

CHT is a leading purification medium of biomolecules in today’s demanding downstream process industry. Its mixed-mode support offers unique selectivities and often separates biomolecules that appear homogeneous with other chromatographic methods. The diverse binding capabilities of CHT for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any stage from initial capture to final polishing.

High throughput and high productivity are standard fare for every Beckman Coulter centrifuge and the Avanti JXN Series is no exception. It’s more than capable of delivering solutions for shared labs, GMP environments, networked instruments and more.

Get more results with the CHO Media Development Kit, which allows you to create a formulation development strategey that fits with your project timeline, resources, and goals.

Baumann 85000 sanitary pinch valves are intended for use with up to 3/4 inch O.D. pharmaceutical grade tubing. They are designed to couple FIELDVUE™ digital valve controller intelligence with a linear actuator and tube shell.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

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