DOWNSTREAM PROCESSING FEATURED ARTICLES
Unraveling The Molecular Roots Of Down Syndrome
What is it about the extra chromosome inherited in Down syndrome—chromosome 21—that alters brain and body development? Researchers have new evidence that points to a protein called sorting nexin 27, or SNX27.
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![1213_BioInnovation_pic]( "Critical Innovation Bioprocessing Trends For 2014")
Critical Innovation Bioprocessing Trends For 2014How the most critical innovations will affect the industry future with the efforts to reduce the costs of manufacturing a biologic, according to the 10th Annual Report and Survey of Biopharmaceutical Manufacturers.
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Kimberly-Clark Professional Launches Innovative RightCycle Program To Recycle Single-Use Cleanroom And Laboratory Gloves And Garments
To provide cleanrooms and laboratories with effective solutions to mitigate waste and enhance Corporate Social Responsibility (CSR) and sustainability efforts, Kimberly-Clark Professional has introduced RightCycle – the first large-scale recycling effort for nontraditional cleanroom waste.
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TAP Collaborates With CCRM On Process Optimisation Project For Cell Therapies
TAP Biosystems, a leading supplier of innovative cell culture systems and consumables for life science applications, has joined the Centre for Commercialization of Regenerative Medicine’s (CCRM) industry consortium to translate laboratory cell culture conditions into optimized processes and media for commercial production of cellular therapies.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Optimized Sterile Filtration of Pharmaceutical Solutions
The cost of filtration and separation stages within the production of pharmaceuticals has been increasing along with the increased complexity of final drug products.
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A Disposable Valve For Process Chromatography
This case study discusses the need for a fully automated, disposable chromatography system which was PLC controlled and designed for use in a cGMP environment. The required applications for the chromatography system included contamination removal, and concentration and purification of biologically derived proteins used in the production of research and clinical materials.
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Comparability Of The Cell-Freeze® (Charter Medical) Freezing Bag To The Cryocyte™ (Baxter) Bag For Cryogenic Storage Of Human Hematopoietic Progenitor Cells Successful cryopreservation of hematopoietic progenitor cells (HPC) is dependent upon a number of factors, including the biopreservation media, freezing rates, and storage using sterile, cryogenically durable storage bags. The Cell-Freeze® cryogenic storage containers are 510(k) cleared for storage, preservation and transfer of hematopoietic progenitor stem cells (HPC’s). By Charter Medical, Ltd.
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![Bill whitford]( "Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate")
Continuous Biomanufacturing: 10 Reasons Sponsors HesitateThe industry is abuzz with talk about continuous biomanufacturing (CB), and its virtues have been well described. Here we will look at some of the barriers or concerns perceived to limit its value to the industry. Justified or not, quite a few concerns have been expressed regarding the implementation of this new, rather disruptive technology.
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Metal Removal From Fine Chemical Products
Metal contamination in various injectable or even oral medicines is a serious concern.
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Biological Contamination Events In Isolators: What Lessons Can Be Learned?
Microbiological deviation and biological contamination events have been observed in pharmaceutical isolators including those used in production, sterility test and pharmacy aseptic services. By James Drinkwater, Bioquell UK Process & Compliance Director
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.