DOWNSTREAM PROCESSING FEATURED ARTICLES
New LIAISON Ixt/Arrow CellSep Advanced Provides Rapid, Automated Cell Separation For Up To Three Cell Types In A Single Run
DiaSorin has launched LIAISON Ixt/Arrow CellSep Advanced for the automated isolation of cells directly from whole blood or buffy coat.
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![PhenomemexTabless-Tube-Hold]( "New SPE Accessories Hold Tubes In 96-Well Spacing For Automated Applications")
New SPE Accessories Hold Tubes In 96-Well Spacing For Automated ApplicationsPhenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces two new Tabless Tube Holder accessories for its Strata and Strata-X lines of silica-based and polymeric solid phase extraction (SPE) sorbents.
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![Phenomenex-Kinetex-1]( "New 1.3-Micron Kinetex Core-Shell Media Delivers Superior UHPLC Performance")
New 1.3-Micron Kinetex Core-Shell Media Delivers Superior UHPLC PerformancePhenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, announces the addition of 1.3-micron UHPLC columns to its Kinetex core-shell product line.
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![Thermo Scientific Exactive Plus image 0521.jpg]( "Thermo Fisher Scientific Introduces Next-Generation Benchtop LC-MS System At ASMS 2012")
Thermo Fisher Scientific Introduces Next-Generation Benchtop LC-MS System At ASMS 2012Thermo Fisher Scientific Inc., the world leader in serving science, recently announced the Thermo Scientific Exactive Plus system, the company’s latest benchtop liquid chromatography-mass spectrometry (LC-MS) system for high-throughput screening, identification and quantification of compounds in complex matrices.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Efficiencies Of Natural Convection In Passive Pallet Shippers
Bulk transportation of temperature sensitive pharmaceuticals and biologics has become a common practice due to complex global supply chains. By Iftekhar Ahmed, Ben VanderPlas, and Stu Krupnick
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Rapid Screening Of A Cell-Based Assay For GLP-1 Receptor Using A Natural Product Library
Here we demonstrate the detection of GLP-1R binding through the incorporation of a homogeneous cell-based binding assay using HTRF Tag-lite® technology. By Brad Larson and Peter Banks, BioTek Instruments, Inc. and Nicolas Pierre, Suzanne Graham, Jean-Luc Tardieu, and François Degorce, Cisbio US, Inc.
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Automation Of A Homogeneous Proximity Assay For Detection Of Residual Protein A In Biological Therapeutics
Protein A is used in affinity chromatography for therapeutic antibody purification and has been shown to leach from columns during purification of antibodies resulting in contamination. Residual Protein A in therapeutic drugs could elicit mitogenic or immunological reactions in patients.
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Biomanufacturing Supply Chains
This white paper examines the major issues with biopharmaceutical supply chains and how to balance inventory and risk optimally in the network.
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Comparing The Automated Pipetting To Volumetric Glassware And Air Displacement Pipettes
Analytical sample preparation is used in many industries such as forensics, environmental chemistry, mining, beer and wine fermentation and many others. Concentrated samples are diluted and analyzed via High Performance Liquid Chromatography, Gas Chromatography, Atomic Absorption, and/or Inductively Coupled Plasma Spectroscopy to name a few. Traditionally these samples are prepared using volumetric glassware, syringes and/or pipettes.
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Removal Of Host Cell Proteins During Monoclonal Antibody Purification
Protein A chromatography is a widely used and highly successful method of purifying recombinant monoclonal antibodies. However, since Protein A has high affinity for antibodies, harsh conditions such as low pH are often required to elute monoclonal antibodies from Protein A affinity columns. By 3M Purification Inc
DOWNSTREAM PROCESSING PRODUCTS
Storage of pharmaceutical compounds is a function of the storage process and not a specific containment driven requirement per se. This is the case whether you are processing in a contained fashion or performing non-contained processing into open kegs with simple drum liners.
The S.U.F. is engineered for optimal oxygen mass transfer, mixing, and temperature control, and performs comparably to traditional stainless steel systems. Using traditional, fundamental engineering principles, scale-up and process development work is streamlined – offering you cost savings and efficiency.
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.