DOWNSTREAM PROCESSING FEATURED ARTICLES
America’s biopharmaceutical research companies are testing 981 medicines and vaccines to fight the many types of canceraffecting millions of patients worldwide, according to a report released today by the Pharmaceutical Research and Manufacturers of America (PhRMA).
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Saving Patients From The Needle Boosts Drug Delivery Company Revenues: Report
Led by needle-free delivery systems the advanced implantable/injectible drug delivery market reached revenues of $13.3 billion in 2012, according to their recently published report Injectable, Implantable and Needle-Free Drug Delivery Systems.
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Galapagos And Roche Conclude Strategic Alliance
Galapagos NV (EURONEXT BRUSSELS: GLPG) announced today that it agreed with Roche to end their alliance in fibrosis.
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HPV Vaccine May Benefit HIV-Infected Women
Women with HIV may benefit from a vaccine for human papillomavirus (HPV), despite having already been exposed to HPV, a study finds. Although many may have been exposed to less serious forms of HPV, more than 45 percent of sexually active young women who have acquired HIV appear never to have been exposed to the most common high-risk forms of HPV, according to the study from a National Institutes of Health research network.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Connection Technology Advances Closed System Processing
The global demand for new biologics and vaccines, combined with the growing emergence of biosimiliars, is challenging drugmakers to re-evaluate their processes and seek ways to make them more flexible, reliable, and cost-effective. By John Boehm, Colder Products Company
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Challenges And Solutions Of Scalable Cultivation For Anchorage Dependent Cells In Single-Use Bioreactor
Microcarrier (MC)-based suspension culture processes have been used to culture anchorage-dependent cells in bioreactors. However, scale-up of the process for high cell growth and productivity poses many challenges. By Brian Lee, Yas Hashimura, Daniel Giroux, Marcos Sousa, Joao Clemente, Manuel Carrondo, Siddharth Gupta, Michael McCaman, and Yong-Jae Kim
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Chromatography Column Protection With 3M Purification LifeASSURE™ PLA Series Membrane Filters Protective, or guard, filters are often used in chromatography column purification steps to protect the column media from contaminants in the various fluids that come in contact with the column.
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Biomanufacturing Debottlenecking And Process Optimization Optimizing biomanufacturing is particularly challenging because of variability and complexity associated with the sharing of finite and interdependent resources. By BIO-G
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Optimizing A Growth Media Filtration System For Mycoplasma Control
Case study on helping a supplier to the biopharmaceutical industry optimize the filtration train they used to sterilize growth media into bioprocess containers while also maintaining Mycoplasma control.
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Turning Data Into Information
As biopharmaceutical manufacturing has evolved from small-scale lab production in small flasks to massive commercial production in deep-tank bioreactors, an avalanche of production data has evolved to support it. From individual unit operation skids to distributed control systems and enterprise resource planning tools, biomanufacturing today is buried by the sheer quantity of data coming in from the manufacturing floor.