DOWNSTREAM PROCESSING FEATURED ARTICLES
Avanti J-26S High Performance Centrifuge Provides Enhanced Environmental, Safety Benefits
The newly redesigned Avanti J-26S high performance centrifuge from Beckman Coulter Life Sciences combines important environmental benefits with increased BioSafety* features.
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Pathobiology Professor's Vaccine Platform Gives Immune Systems A Boost
Dr. Bernhard Kaltenboeck, professor of pathobiology in Auburn University’s College of Veterinary Medicine, and research associates Erfan Chowdhury and Yihang Li have developed a vaccine platform to treat intracellular diseases for which antibodies are ineffective.
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Cloak And Swagger: Engineers Use Plasmonics To Create An Invisible Photodetector
It may not be intuitive, but a coating of reflective metal can actually make something less visible, engineers at Stanford and UPenn have shown. They have created an invisible, light-detecting device that can “see without being seen.” By Andrew Myers
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Is The Single-Use Standardization Debate Slowing Down Adoption?
Without single-use standardization, the customization required to build a single-use facility may prevent a full-scale adoption of single-use technology. So how do we move forward? Maybe, by taking a look back.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Materials Of Construction For Biopharmaceutical Water Systems
Stainless steels are uniquely qualified for bioprocessing applications not only because of their long service life, availability, and fabricability, but also because they are non-corroding, non-contaminant, can be polished to very smooth finishes, are strong and rigid, can withstand heat and chemical sterilization treatments, and are easily welded. By Michelle M. Gonzalez
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Comparison Of Five Cell Culture Media Demonstrating CHO Cell Culture Growth In Batch Or Fed-Batch Process For Commercial Operations
This case study details a two month, four phase project to design chemically-defined feed media that improved two simulated batch processes utilizing products by SAFC, Life Technologies, Thermo Fisher Scientific, and Irvine Scientific. By Mark C. Arjona, Evan R. Horowitz, Alex A. Jurisch, Jenny Y. Bang, Tom Fletcher, Irvine Scientific
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White Paper: Comparability Of The Cell-Freeze® (Charter Medical) Freezing Bag To The Cryocyte™ (Baxter) Bag For Cryogenic Storage Of Human Hematopoietic Progenitor Cells Successful cryopreservation of hematopoietic progenitor cells (HPC) is dependent upon a number of factors, including the biopreservation media, freezing rates, and storage using sterile, cryogenically durable storage bags. The Cell-Freeze® cryogenic storage containers are 510(k) cleared for storage, preservation and transfer of hematopoietic progenitor stem cells (HPC’s). By Charter Medical, Ltd.
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Selecting The Optimal Resins For Endotoxin Depletion In Process Purification
A guide to effectively remove endotoxins with versatile process resins.
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Biomanufacturing Complexity
This white paper addresses one of the most serious challenges facing biomanufacturing professionals today - how to understand and then deal with the extreme complexity associated with biotechnology manufacturing.
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Economic Analysis Of Single-Use Tangential Flow Filtration For Biopharmaceutical Applications Prior to creating an accurate economic model for TFF, a thorough understanding of the process where the TFF is used is needed. A process model is a valuable tool when properly executed and it must accurately include all critical aspects of the purification process. By Michael LaBreck, Mark Perreault, Novasep