DOWNSTREAM PROCESSING FEATURED ARTICLES

Pfenex Awarded Contract By The NIAID To Develop An Alternative Delivery Method For rPA-based Anthrax Vaccine

Pfenex Inc. Awarded Contract by the National Institute of Allergy and Infectious Diseases  (NIAID) to Develop an Alternative Delivery Method for its Recombinant Protective Antigen (rPA)-based Anthrax Vaccine

  • Study Points To Possible Cause Of, And Treatment For, Non-Familial Parkinson's

    Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson’s disease.

  • Stellar Biotechnologies Announces Filing A US Letters Patent Application

    Stellar Biotechnologies, Inc. ("Stellar" or the "Company") (TSX VENTURE: KLH) (PINKSHEETS: SBOTF) (FRANKFURT: RBT) is very pleased to announce the filing of a US Letters Patent Application directed to protecting certain proprietary KLH manufacturing controls, KLH formulations and kits used in immunotoxicology and immune status testing which were invented by Drs. Chow, Sundsmo and Sagermann.

  • Scientists Help Identify A Missing Link In Taste Perception

    Working with a multidisciplinary consortium of 19 researchers from nine institutions, Monell scientists have provided critical information to identify CALHM1, a channel in the walls of taste receptor cells, as a necessary component in the process of sweet, bitter, and umami (savory) taste perception.

DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

DOWNSTREAM PROCESSING PRODUCTS

Water for Injection (WFI) Quality Water is the most suitable water available for producing cell culture media, reconstitution of biochemical reagents, and as a final rinse water for critical applications. WFI Quality Water meets both EP and USP grade specifications and is 0.1µm sterile filtered at time of fill.

WHEATON’s selection of chromatography vials and accessories offers quality, value and reliability. WHEATON chromatography vials are designed for trouble-free operation in most autosamplers.

New C-Flex® ULTRA pump tubing is the latest addition to the C-Flex family of thermoplastic elastomer (TPE) tubing. Specifically designed to meet the critical demands of the biopharmaceutical industry, C-Flex® ULTRA outperforms all other TPE materials on the market today.

Amsphere™ A3 is a next generation Protein A chromatography resin for advanced protein separation in downstream processing of therapeutic antibodies manufacturing. With high capacity resin, Amsphere™ A3 has an overall improved process robustness, flow characteristics, optimized impurity removal, productivity and resin lifetime.

The ReadyToProcess WAVE 25 rocker features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures up to 25 L. A filter heater is delivered with the system.

The SPRIworks Fragment Library Systems have built-in size selection and prepare fragment libraries for all three major next generation sequencing platforms. SPRIworks Systems simplify and automate fragment library construction for the Illumina Genome Analyzers, Roche GS FLX DNA Sequencer and Life Technologies SOLiD Sequencers.

This is an exciting platform technology for cell cultivation. It is a highly versatile process which permits great increases in cell and product concentrations as compared to Fed Batch processing.

Protein A based affinity chromatography is the industry standard for the capture of monoclonal antibodies (MAbs) in downstream processing.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

DOWNSTREAM PROCESSING INDUSTRY NEWS