DOWNSTREAM PROCESSING FEATURED ARTICLES

Evotec Acquires Cell Culture Service GmbH

Evotec AG recently announced the acquisition of all shares in Cell Culture Service GmbH (CCS), a Hamburg-based company which supports the cell culture needs of a world-wide customer base of biotech and Pharmaceutical companies.

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This is an exciting platform technology for cell cultivation. It is a highly versatile process which permits great increases in cell and product concentrations as compared to Fed Batch processing.

The Emphaze Hybrid Purifier is a new single-use clarifying device containing a multi-mechanism all synthetic Q-functional anion exchange media integrated with a fine particle, bioburden reduction membrane. The anion exchange media is comprised of a quaternary amine hydrogel supported by a fine fiber nonwoven scaffold. A combination of 3M technology platforms enables the hyperfunctionalization of a high purity polypropylene nonwoven with a covalently attached, thermally stable, water soluble polymer; the functional polymer accounts for roughly two-thirds of the mass of the anion exchange media. The bioburden reduction membrane is a highly asymmetric, high loading capacity polyamide membrane which has nine zones of decreasing pore size spanning a roughly 20X range and terminating with a 0.2 μm bioburden reduction rated pore size.

BioTek’s Take3™ and Take3™ Trio Micro Volume Plates are designed to increase the functionality of your BioTek microplate spectrophotometer, multi-mode or Hybrid reader by decreasing the sample size required to a mere 2 µL.

Complement your gene expression analysis with LOH studies. Confirm your SNP analysis results by sequencing. Combine MLPA genomic results with quantitative gene expression for the full story.

The SoftGrip pipette and Hamiton AdvanTip Precision Pipette Tips create a liquid handling system designed for optimal performance. Ensure you are getting the Hamilton accuracy and precision advantage by using only Hamilton AdvanTip Precision Pipette Tips.

PreSens offers a new system for measuring oxygen and pH in shake flasks. The SFR – Shake Flask Reader measures rapid and precise in up to 9 shake flasks simultaneously. This novel device is used for microbial cultivations and cell cultures.

3M Purification Inc.’s LifeASSURE™ PDA series filter combines two asymmetric polyethersulfone (PES) membrane layers together with proprietary Advanced Pleat Technology (APT) design.

Proyield Pea PCE80B is a protein hydrolysate derived from pea protein concentrate by enzymatic hydrolysis. The enzymes used for digestion are from non-animal sources. Proyield Pea PCE80B has been ultrafiltered to reduce endotoxin.

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Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

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