DOWNSTREAM PROCESSING FEATURED ARTICLES

3M Purification Inc. Introduces New Zeta Plus Encapsulated, Single-Use Depth Filtration Products

3M Purification Inc. has expanded its portfolio of Encapsulated Zeta Plus single-use depth filtration capsules.  The two new product lines – Zeta Plus Scale-up Capsule Filters and new single-layer media grades for Zeta Plus Encapsulated capsules – are designed with our industry leading Zeta Plus depth filter media, designed for applications in the bio-pharmaceutical industry including cell culture clarification, downstream process protection, virus, DNA and lipid reduction, and host cell protein (HCP), protein aggregate, endotoxin and anti-foaming agent removal.

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BioTek’s Take3™ and Take3™ Trio Micro Volume Plates are designed to increase the functionality of your BioTek microplate spectrophotometer, multi-mode or Hybrid reader by decreasing the sample size required to a mere 2 µL.

The SPRIworks Fragment Library Systems have built-in size selection and prepare fragment libraries for all three major next generation sequencing platforms. SPRIworks Systems simplify and automate fragment library construction for the Illumina Genome Analyzers, Roche GS FLX DNA Sequencer and Life Technologies SOLiD Sequencers.

Pure-Fit® SC is an innovative new connective technology that makes it possible to create true sterile connections anywhere – even outside the clean room environment.

The Emphaze Hybrid Purifier is a new single-use clarifying device containing a multi-mechanism all synthetic Q-functional anion exchange media integrated with a fine particle, bioburden reduction membrane. The anion exchange media is comprised of a quaternary amine hydrogel supported by a fine fiber nonwoven scaffold. A combination of 3M technology platforms enables the hyperfunctionalization of a high purity polypropylene nonwoven with a covalently attached, thermally stable, water soluble polymer; the functional polymer accounts for roughly two-thirds of the mass of the anion exchange media. The bioburden reduction membrane is a highly asymmetric, high loading capacity polyamide membrane which has nine zones of decreasing pore size spanning a roughly 20X range and terminating with a 0.2 μm bioburden reduction rated pore size.

The ATF™ System was originally designed for perfusion processes in mammalian cell culture, using hollow fiber filters to achieve an efficient cell separation with low shear and allowing robust large scale manufacturing.

Choose from ten fixed volume SoftGrip pipettes covering 0.2 µL to 1 mL. All pipettes have color-coded plunger buttons and labels for easy volume identification.

The Allegra X-30 Series Benchtop Centrifuges were designed with your needs in mind providing you with excellent performance and easy operation in a compact design that saves you valuable time and laboratory space.
Agilent's GeneSpring GX software provides powerful, accessible statistical tools for fast visualization and analysis of transcriptomics, genomics, proteomics and metabolomics data.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

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