MorphoSys Receives First Patent On Novel Antibody Platform Ylanthia In The US

MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX) today announced that the US Patent and Trademark Office (USPTO) has granted the first patent covering the Company's latest antibody platform Ylanthia, which became commercially available for existing and new partners in 2012.

  • Damania Lab Discovers Gene That Suppresses Herpesviruses

    In a paper published by Cell Host and Microbe on Feb. 13, a research team led by Blossom Damania, PhD, of the Department of Microbiology and Immunology and member of the UNC Lineberger Comprehensive Cancer Center, found that suppressing the TLK enzyme causes the activation of the lytic cycle of both EBV and KSHV. During this active phase, these viruses begin to spread and replicate, and become vulnerable to anti-viral treatments.

  • Making The Switch To Single-Use: Have You Thought Of Everything?
    Making The Switch To Single-Use: Have You Thought Of Everything?

    In 2014, Prolong Pharmaceuticals followed through with a decision to build a facility for the scale-up of their lead product, SANGUINATE. As part of this decision, the new facility would not utilize Prolong’s traditional manufacturing process and would instead switch to one that uses single-use technology (SUT) almost exclusively. Chuck Hart, Prolong’s director of manufacturing, recently sat down with me to discuss some areas he feels are sometimes overlooked when switching from traditional stainless steel to SUT.

  • Newfound Gene May Help Bacteria Survive In Extreme Environments

    In the days following the 2010 Deepwater Horizon oil spill, methane-eating bacteria bloomed in the Gulf of Mexico, feasting on the methane that gushed, along with oil, from the damaged well. The sudden influx of microbes was a scientific curiosity: Prior to the oil spill, scientists had observed relatively few signs of methane-eating microbes in the area. By Jennifer Chu, MIT

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  • Biomanufacturing Flexibility

    This white paper from BIO-G looks at how to create flexible, agile manufacturing facilities to respond to the current glut of biomanufacturing capacity and industry consolidation. Future proofing these facilities for higher titers and multiple product lines is also explored.

  • Compound Profiling And Toxicity
    Compound Profiling And Toxicity

    Utilizing a systems approach to drug discovery has generated a multitude of high affinity compounds for various classes of molecular targets with different degrees of disease state validation.

  • Microbial Fermentation In Single-Use Xcellerex™ XDR-50 MO Fermentor System
    Microbial Fermentation In Single-Use Xcellerex™ XDR-50 MO Fermentor System

    This application note describes the performance of a single-use Xcellerex XDR-50 bioreactor system when used in cultivations of E. coli and of modified Pseudomonas fluorecsens (P. fluorescens) producing a monoclonal antibody (MAb). Both the achieved microbe densities and product yield were shown to be consistent with the performance of conventional stainless steel systems.

  • Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate
    Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate

    By William Whitford, Strategic Solutions Leader, BioProcess, GE Healthcare Life Sciences

    The industry is abuzz with talk about continuous biomanufacturing (CB), and its virtues have been well described. Here we will look at some of the barriers or concerns perceived to limit its value to the industry. Justified or not, quite a few concerns have been expressed regarding the implementation of this new, rather disruptive technology. 

  • High Efficiency Separations At Any pH Or Mobile Phase
    High Efficiency Separations At Any pH Or Mobile Phase

    The Hamilton PRP-C18 is a new column designed to provide high efficiency reversed phase separations over an extended column life in nearly any mobile phase or pH.

  • An Automated Profiling Application For G9a Histone Methyltransferase And Bromodomain Proteins

    Due to several findings, G9a and BET bromodomain proteins have become the target for numberous drug discovery projects. In this study, we describe a novel, cell-based assay platform that uses the robust, yet simple Enzyme Fragment Complementation (EFC) Technology.

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Liquid Handling OEM Liquid Handling OEM

When your instrumentation requires fluid handling equipment, you need more than parts—you need a partner. And that partner is Hamilton Company.

Viscotek TDAmax: Gel Permeation / Size Exclusion Chromatography (GPC/SEC) Viscotek TDAmax: Gel Permeation / Size Exclusion Chromatography (GPC/SEC)

The Viscotek TDAmax is a complete, research grade, temperature controlled, multi-detector GPC/SEC system suitable for the molecular weight and molecular size determination of proteins, natural and synthetic polymers, copolymers and other macromolecules. 

Centrifugation: Allegra X-12 Centrifuge Centrifugation: Allegra X-12 Centrifuge
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Sterilizing Grade PES Filters: LifeASSURE™ PDA Sterilizing Grade PES Filters: LifeASSURE™ PDA

3M Purification Inc.’s LifeASSURE™ PDA series filter combines two asymmetric polyethersulfone (PES) membrane layers together with proprietary Advanced Pleat Technology (APT) design.

Fermentation Systems Fermentation Systems

Whether you prefer the convenience of a single-use bioreactor, the flexibility of an autoclavable system, or the robustness of a sterilizable-in-place (SIP) production-scale reactor, we have a system right for you.

XS Microbial Expression Technologies™ XS Microbial Expression Technologies™
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Beckman Coulter High Capacity Centrifuge:  Avanti® J-HC Beckman Coulter High Capacity Centrifuge: Avanti® J-HC

The Avanti® J-HC High Capacity Centrifuge provides you with a complete solution for batch bioprocessing. A maximum of 9 Liters can be spun at speeds of 5,000 rpm and 7,480 x g for greater sample throughput. This allows processing of up to 36 Liters per hour when harvesting bacteria. Enhanced operator safety is provided with disposable HarvestLine System Liners.

IVD Magnetic Beads: Magnosphere™ IVD Magnetic Beads: Magnosphere™

Magnosphere™ is a superparamagnetic particle for in vitro diagnostics and bio research applications.

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Optima X Series Ultracentrifuge: Energy Efficient Technology, Real-Time Data Tracker

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Large Scale Automated Depth Filtration Video

The Zeta Plus Encapsulated System product portfolio for single-use depth filtration has been expanded to include the Model# 16EZC Multi-Round Holder.

GE Healthcare At AAPS: FTA DMPK Cards

Jim Robbins and Julie Hilton Demonstrate GE Healthcare's Whatman Indicating FTA DMPK cards.

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