DOWNSTREAM PROCESSING FEATURED ARTICLES

HPV Vaccine May Benefit HIV-Infected Women

Women with HIV may benefit from a vaccine for human papillomavirus (HPV), despite having already been exposed to HPV, a study finds. Although many may have been exposed to less serious forms of HPV, more than 45 percent of sexually active young women who have acquired HIV appear never to have been exposed to the most common high-risk forms of HPV, according to the study from a National Institutes of Health research network.

  • Endress+Hauser Introduces OUSBT66 Cell Density Sensor

    Endress+Hauser introduces the OUSBT66 sensor for cell density measurement. Using near-Infrared (NIR) light absorbance technology, the OUSBT66 is a non-intrusive, hygienic sensor that is ideal for real time, in-situ cell production optimization in life science processes, fermentation biomass measurement and algae growth monitoring for biofuel production.

  • High-Flow Sterile Connectors For Single-Use Applications

    Over the past decade, two developments have increased demand for high fl ow-rate connectors: Size advances in single-use bioreactors up to 2000L and the  implementation of single-use downstream.

  • Single-Use BioFlex Tubing Assemblies Featured In New Brochure Meissner has just released a new brochure featuring its BioFlex tubing assemblies. The single-use tubing assemblies are designed for secure fluid transfer in critical biopharmaceutical processing applications.

DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

DOWNSTREAM PROCESSING PRODUCTS

Macro-Prep hydrophobic interaction chromatography (HIC) media are methacrylate-based, 50 µm beads used for protein, polypeptide, enzyme, and nucleic acid purification.

Hydrophilic media and depth filters. Cellulosic, Diatomaceous earth + cellulose, GF, polyproylene and nano fiber disposable capsules or cartridges. For clarification, prefiltration or to protect columns. Many different inlet / outlet connections, with or without vents and drains. SIP / Autoclavable. Specify when gamma stability is required.

Designed with a smaller footprint so it will fit right in your lab, the Avanti J-E is compact yet powerful. The Avanti J-E’s extensive rotor library maximizes capacity and optimizes g-force for efficient, fast separations and greater variety of applications. Its high-torque, switched reluctance (SR) drive technology delivers faster acceleration and deceleration, which means less wait time for you. It offers an intuitive, user-friendly interface, as well as lower energy costs. What’s more, the Avanti J-E’s low height and contoured front panel help ease the burden of rotor installation and retrieval, for even more convenient operation.

CHT is a leading purification medium of biomolecules in today’s demanding downstream process industry. Its mixed-mode support offers unique selectivities and often separates biomolecules that appear homogeneous with other chromatographic methods. The diverse binding capabilities of CHT for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any stage from initial capture to final polishing.

Freeze drying is a potentially damaging process, especially to labile materials such as proteins or living organisms. Depending on the product type damage can occur at various stages of the process including freezing, drying and heating.

The S.U.F. is engineered for optimal oxygen mass transfer, mixing, and temperature control, and performs comparably to traditional stainless steel systems. Using traditional, fundamental engineering principles, scale-up and process development work is streamlined – offering you cost savings and efficiency. 
 

In an effort to push science forward, WHEATON is manufacturing  a new line of membrane driven flasks for high density cell culture. The flasks are designed to enhance small scale bio-production for antibody and protein generation.

When your instrumentation requires fluid handling equipment, you need more than parts—you need a partner. And that partner is Hamilton Company.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

DOWNSTREAM PROCESSING INDUSTRY NEWS