DOWNSTREAM PROCESSING FEATURED ARTICLES
Stellar Biotechnologies Announces Filing A US Letters Patent Application
Stellar Biotechnologies, Inc. ("Stellar" or the "Company") (TSX VENTURE: KLH) (PINKSHEETS: SBOTF) (FRANKFURT: RBT) is very pleased to announce the filing of a US Letters Patent Application directed to protecting certain proprietary KLH manufacturing controls, KLH formulations and kits used in immunotoxicology and immune status testing which were invented by Drs. Chow, Sundsmo and Sagermann.
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![untitled]( "GE Healthcare Launches ÄKTA™ Pure, A New Modular Chromatography System For Protein Purification")
GE Healthcare Launches ÄKTA™ Pure, A New Modular Chromatography System For Protein PurificationGE Healthcare, the healthcare business of GE announced recently the launch of ÄKTA™ pure, a chromatography system for flexible, reliable and intuitive purification of proteins.
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![Untitled]( "Stainless Steel Vial Filling System Developed For Use In Vaccine Facilities")
Stainless Steel Vial Filling System Developed For Use In Vaccine FacilitiesTAP Biosystems (now part of the Sartorius Stedim Biotech Group), a leading supplier of innovative cell culture and fermentation systems for life science applications, recently announced the development of a stainless steel version of the fill-it system, designed for safely dispensing biohazardous materials such as vaccine stocks.
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Damania Lab Discovers Gene That Suppresses Herpesviruses
In a paper published by Cell Host and Microbe on Feb. 13, a research team led by Blossom Damania, PhD, of the Department of Microbiology and Immunology and member of the UNC Lineberger Comprehensive Cancer Center, found that suppressing the TLK enzyme causes the activation of the lytic cycle of both EBV and KSHV. During this active phase, these viruses begin to spread and replicate, and become vulnerable to anti-viral treatments.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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![Bill whitford]( "Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate")
Continuous Biomanufacturing: 10 Reasons Sponsors HesitateThe industry is abuzz with talk about continuous biomanufacturing (CB), and its virtues have been well described. Here we will look at some of the barriers or concerns perceived to limit its value to the industry. Justified or not, quite a few concerns have been expressed regarding the implementation of this new, rather disruptive technology.
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CD69 Expression On Activated Lymphocytes Is Stable In Streck's Cyto-Chex® BCT
The purpose of this study was to determine if the activation marker, CD69, is preserved and stable in whole blood samples collected in Cyto-Chex® BCT. Previous studies have demonstrated CD marker stability of whole blood samples collected in Cyto-Chex BCT for up to 7 days when stored at room temperature (18-22°C). By Jodi Alt, Ph.D
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Rapid Chemically-Defined Feed Media Development to Improve Simulated Cell Culture Processes
Implementing an optimized feed medium may be the most effective alternative for modifications to the growth medium in an existing process.
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Protein A Alternatives: Mixed Mode Resins For High Throughput mAb Feedstocks
Mixed mode resins can serve as an alternative to protein A in intermediate processing. Implementation of mixed mode resins can reduce water required for filtration and time for column loading.
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![Bacteria 450x300]( "Selecting The Optimal Resins For Endotoxin Depletion In Process Purification")
Selecting The Optimal Resins For Endotoxin Depletion In Process PurificationA guide to effectively remove endotoxins with versatile process resins.
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Efficiencies Of Natural Convection In Passive Pallet Shippers
Bulk transportation of temperature sensitive pharmaceuticals and biologics has become a common practice due to complex global supply chains. By Iftekhar Ahmed, Ben VanderPlas, and Stu Krupnick
DOWNSTREAM PROCESSING PRODUCTS
Cytiva provides filtration solutions and support for integrated bioprocessing applications at every step and every scale of the drug development, validation and manufacturing process.
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.