DOWNSTREAM PROCESSING FEATURED ARTICLES
Ultrasound Idea: Prototype NIST/CU Bioreactor Evaluates Engineered Tissue While Creating It
Researchers at the National Institute of Standards and Technology (NIST) have developed a prototype bioreactor—a device for culturing cells to create engineered tissues—that both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis.
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![genderlesssterileconnectors]( "The Benefits Of Genderless Sterile Connectors For Single-Use Applications")
The Benefits Of Genderless Sterile Connectors For Single-Use ApplicationsGenderless connections are those in which the connector halves are identical in design, thus eliminating the need for different male and female halves to make the connection.
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Virus Engineered To Express Melanin Offers New Possibilities To Diagnose And Treat Solid Tumor Cancers
In a study released today in Proceedings of the National Academy of Sciences (PNAS), entitled "Vaccinia virus mediated melanin production allows MR and optoacoustic deep tissue imaging and laser induced thermotherapy of cancer," scientists combined the natural imaging potential of melanin with recombinant Vaccinia viruses' ability to selectively enter and replicate within tumor cells.
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![Single-use Connectors]( "The Value of Closing Your Process")
The Value of Closing Your ProcessFor R&D and PD applications, closed, single-use systems can protect against both biological and cross-contamination, saving valuable research time and money.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Biomanufacturing Supply Chains
This white paper examines the major issues with biopharmaceutical supply chains and how to balance inventory and risk optimally in the network.
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Optimized Sterile Filtration of Pharmaceutical Solutions
The cost of filtration and separation stages within the production of pharmaceuticals has been increasing along with the increased complexity of final drug products.
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![DebottleneckingCartoon]( "Biomanufacturing Debottlenecking And Process Optimization")
Biomanufacturing Debottlenecking And Process OptimizationOptimizing biomanufacturing is particularly challenging because of variability and complexity associated with the sharing of finite and interdependent resources. By BIO-G
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Rapid Chemically-Defined Feed Media Development to Improve Simulated Cell Culture Processes
Implementing an optimized feed medium may be the most effective alternative for modifications to the growth medium in an existing process.
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![CrystalStructure]( "How CHT Ceramic Hydroxyapatite Works Application Note")
How CHT Ceramic Hydroxyapatite Works Application NoteCHT ceramic hydroxyapatite is a versatile chromatography support used for separation of biological molecules as diverse as polyclonal and monoclonal antibodies, antibody fragments, enzymes, nucleic acids, and membrane proteins. By Paul Ng, Jie He, and Andrew Cohen, Bio-Rad Laboratories, Inc., Hercules, CA 94547
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Biomanufacturing Complexity
This white paper addresses one of the most serious challenges facing biomanufacturing professionals today - how to understand and then deal with the extreme complexity associated with biotechnology manufacturing.
DOWNSTREAM PROCESSING PRODUCTS
The ReadyToProcess WAVE 25 rocker features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures up to 25 L. A filter heater is delivered with the system.
AseptiQuik® STC Connectors integrate the AseptiQuik® sterile connector and the Steam-Thru® II SIP connector, giving manufacturers even greater flexibility for hybrid stainless steel and single-use processing.
Magnosphere™ is a superparamagnetic particle for in vitro diagnostics and bio research applications.
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.