DOWNSTREAM PROCESSING FEATURED ARTICLES

FDA Approves First Drug-Eluting Stent To Treat Peripheral Arterial Disease

The U.S. Food and Drug Administration approved the Zilver PTX Drug-Eluting Peripheral Stent (Zilver PTX Stent), the first drug-eluting stent indicated to re-open a particular artery in the thigh (femoropopliteal artery) when narrowed or blocked as a result of peripheral artery disease (PAD).

DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

DOWNSTREAM PROCESSING PRODUCTS

PureFlo hydrophobic polyethylene (PE) membrane filters, gamma compatible and ideal alternative to PVDF. Mold injected capsules with multiple inlet / outlet options including sanitary ‘T’ clamps, hose barbs, quick sanitary connectors, elbows and threads. Almost any combination of connecting inlet or outlet is possible with over 30 options. High gas flow at low differential pressure due to encapsulation geometries and polyethylene (PE) membrane. Full validation supporting documents are available. Ideal for tube sets and hook up to bioreactors, fermenters, biocontainer, biobags, wave bags or single use fermenters.

ZenPure’s in-company mold design and injection capabilities, filter production and quality assurance facilitate manufacturing audit and product traceability that meet the highest industry standards.

The QAII Station has been designed to ensure each tested dissolution apparatus conforms with mechanical specifications.

ARC Sensors are the complete solution: innovative premium quality sensors with a robust, direct, and standard interface to the PLC. Hamilton ARC Sensors send a 4-20 mA signal directly to an analog process control system while delivering at the same time the power of digital sensor management.

It spins volumes.

With six-liter capacity and an innovative range of rotors, carriers, and adapters, this versatile centrifuge can handle multiple high capacity applications. Ideal for bioprocessing and clinical and blood sample preparation, the J6-MI is the standard for quiet and convenient operation.

With the Eppendorf BioSpectrometer basic, measurements can be executed in the UV and Vis range from 200 nm to 830 nm. The freely selectable wavelengths offer you maximum flexibility during these procedures.

A proven method for confirming protein purity and yield without the need for gel staining steps. Stain-free gels provide visual confirmation of protein purity and yield by gel electrophoresis in less than 30 minutes. Stain-free technology is perfect for drug discovery, drug development, and method development for preclinical research.

CHT is a leading purification medium of biomolecules in today’s demanding downstream process industry. Its mixed-mode support offers unique selectivities and often separates biomolecules that appear homogeneous with other chromatographic methods. The diverse binding capabilities of CHT for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any stage from initial capture to final polishing.

The Avanti J-30I High-Performance Centrifuge System gives you the fastest separations possible - in the shortest amount of time. Swinging-bucket and fixed-angle rotors provide maximum separation forces in excess of 100,000 x g at speeds up to 30,000 rpm.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

DOWNSTREAM PROCESSING INDUSTRY NEWS