DOWNSTREAM PROCESSING FEATURED ARTICLES
GeoVax Labs, Inc. (
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Scientists Show Protein-Making Machinery Can Switch Gears With A Small Structural Change
For the past several years, Min Guo, an assistant professor at The Scripps Research Institute (TSRI), has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins.
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NIH-Funded Researchers Create Next-Generation Alzheimer's Disease Model
A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer’s disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the disease, according to a study, published in the Journal of Neuroscience.
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New 1.3-Micron Kinetex Core-Shell Media Delivers Superior UHPLC Performance
Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, announces the addition of 1.3-micron UHPLC columns to its Kinetex core-shell product line.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Chromatography Column Protection With 3M Purification LifeASSURE™ PLA Series Membrane Filters Protective, or guard, filters are often used in chromatography column purification steps to protect the column media from contaminants in the various fluids that come in contact with the column.
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Rapid Chemically-Defined Feed Media Development to Improve Simulated Cell Culture Processes
Implementing an optimized feed medium may be the most effective alternative for modifications to the growth medium in an existing process.
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Improving Aggregate Removal From mAb Feed Using Cation Exchange Chromatography
Researchers in the field of chromatography have required ever more sophisticated and selective methods for removing aggregates from the monomer.
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Continuous Harvesting Of Extra-Cellular Proteins From Mammalian Cell Cultures Utilizing Small-Scale Perfusion
The use of a small-scale cell culture system not only maximizes the production of valuable protein but also avoids the high capital cost associated with system scale-up. Continuous harvesting can provide significant improvements in protein yields when compared to those of typical batch operations.
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Single-Use Connections Advance Aseptic Processing
John Boehm discusses how single-use connections advance aseptic processing and create increased process flexibility and reliability while reducing costs.
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Examining Column Reproducibility During Method Development In Clinical Labs
In this study demonstrates how the HSS T3 stationary phase is a reliable stationary phase, as three batches made over a five-year span provide comparable results.