DOWNSTREAM PROCESSING FEATURED ARTICLES
A new biofuel production process created by Michigan State University researchers produces 20 times more energy than existing methods.
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![22275]( "RNA-Based Therapy Brings New Hope For An Incurable Blood Cancer")
RNA-Based Therapy Brings New Hope For An Incurable Blood CancerThree thousand new cases of Mantle Cell Lymphoma (MCL), a form of blood cancer, appear in the United States each year. With a median survival span of only five to seven years, according to the Leukemia and Lymphoma Society, this disease is devastating, and new therapies are sorely needed.
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![PBS3.jpg]( "PBS Biotech Launches Single-Use Bioreactor For Development Of New Vaccines And Biosimilars")
PBS Biotech Launches Single-Use Bioreactor For Development Of New Vaccines And Biosimilars PBS Biotech, Inc., a developer of state of the art bioreactors to be used in the fast growing biotechnology market, announced recently the launch of its innovative PBS 3 single-use bioreactor system. -
NIH-Funded Researchers Create Next-Generation Alzheimer's Disease Model
A new genetically engineered lab rat that has the full array of brain changes associated with Alzheimer’s disease supports the idea that increases in a molecule called beta-amyloid in the brain causes the disease, according to a study, published in the Journal of Neuroscience.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Micro-Volume Determination Of Labeling Efficiency In A Standard Microplate Reader
A variety of methods and reagents have been developed to efficiently label biomolecules. By Peter J. Brescia, Applications Scientist, BioTek Instruments, Inc.
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Automated Bioluminescent ADCC Reporter Bioassay Using Bioengineered Jurkat Cells
Pharmaceutical companies are increasingly exploring new biologic and biosimilar products, and thus increasing monoclonal antibody (mAb) immunotherapeutic research. By Tracy Worzella, Promega Corporation and Brad Larson, Applications Department, BioTek Instruments, Inc.
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Top 10 Considerations When Selecting An Isolator Supplier
While price is certainly an important reason for buying any piece of capital equipment, it is not always the top reason. There are important considerations to examine when selecting an isolator supplier.
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An Automated Profiling Application For G9a Histone Methyltransferase And Bromodomain Proteins
Due to several findings, G9a and BET bromodomain proteins have become the target for numberous drug discovery projects. In this study, we describe a novel, cell-based assay platform that uses the robust, yet simple Enzyme Fragment Complementation (EFC) Technology.
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Proven Long Life Lasers™ In Optical Particle Counters Optical particle counters (OPC) utilize light illumination and extinction to determine the presence, size, number and/or concentration of particles. Particles are typically suspended in a fluid or air, which flow through the volume that is illuminated and viewed by the detection system.
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![Bio-rad]( "Improving Aggregate Removal From mAb Feed Using Cation Exchange Chromatography")
Improving Aggregate Removal From mAb Feed Using Cation Exchange ChromatographyResearchers in the field of chromatography have required ever more sophisticated and selective methods for removing aggregates from the monomer.
DOWNSTREAM PROCESSING PRODUCTS
ÄKTA™ chromatography systems can handle both simple and complex purification tasks and accelerate daily routines. All systems are controlled by UNICORN™ software, a common control platform and user interface for all scales of operation.
Macro-Prep hydrophobic interaction chromatography (HIC) media are methacrylate-based, 50 µm beads used for protein, polypeptide, enzyme, and nucleic acid purification.
Storage of pharmaceutical compounds is a function of the storage process and not a specific containment driven requirement per se. This is the case whether you are processing in a contained fashion or performing non-contained processing into open kegs with simple drum liners.
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.