DOWNSTREAM PROCESSING FEATURED ARTICLES

New Monoclonal Antibody Developed That Can Target Proteins Inside Cancer Cells

Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells.

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DOWNSTREAM PROCESSING PRODUCTS

Designed with a smaller footprint so it will fit right in your lab, the Avanti J-E is compact yet powerful. The Avanti J-E’s extensive rotor library maximizes capacity and optimizes g-force for efficient, fast separations and greater variety of applications. Its high-torque, switched reluctance (SR) drive technology delivers faster acceleration and deceleration, which means less wait time for you. It offers an intuitive, user-friendly interface, as well as lower energy costs. What’s more, the Avanti J-E’s low height and contoured front panel help ease the burden of rotor installation and retrieval, for even more convenient operation.

Get more results with the CHO Media Development Kit, which allows you to create a formulation development strategey that fits with your project timeline, resources, and goals.

All Hamilton General Use Housings/Armatures have an integrated electrode protection design to prevent possible damage of the electrode membrane due to solid components in the sample.

CHO Feed 3 is a chemically-defined protein-free feed medium of non-animal origin. Using Irvine Scientific’s Rational Culture Media Design™ approach, this formulation has been developed to achieve high growth kinetics and product yield in fed-batch processes.

Sterilizing grade 0.04um, 0.1um, 0.2um hydrophilic PES membrane filters plus other micron ratings. Single layer or double layer PES and with optional prefilter layers to extend on-stream life. Gamma compatible and suitable PVDF alternative. Mold injected capsules with multiple inlet / outlet options including sanitary ‘T’ clamps, hose barbs, quick sanitary connectors, elbows and threads. Almost any combination of connecting inlet or outlet is possible with over 30 options. Full validation supporting documents are available. Ideal for tube sets and hook up to bioreactors, fermenters, biocontainer, biobags, wave bags or single use fermenters.

ZenPure’s in-company mold design and injection capabilities, filter production and quality assurance facilitate manufacturing audit and product traceability that meet the highest industry standards.

3M Purification's core filtration technologies address the most demanding applications in pharmaceutical processing for small molecule and active pharmaceutical ingredient (API) applications.

Nuvia HR-S media is a new strong cation exchanger that has been optimized for particle size and chemistry that provides exceptional resolution and high recovery.

Bio-Beads SM-2 nonpolar polystyrene adsorbents are analytical grade, neutral macroporous polymeric beads for use in hydrophobic interaction chromatography.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

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