DOWNSTREAM PROCESSING FEATURED ARTICLES

Article: How To Choose An Industrial Cation Exchanger For IgG Purification

Cation-exchange chromatography is the third most used industrial method for antibody purification after anion-exchange and protein A affinity chromatography. It is most commonly used as an intermediate step but continues to attract attention as a capture method. By Pete Gagnon

DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

DOWNSTREAM PROCESSING PRODUCTS

BioTek’s Take3™ and Take3™ Trio Micro Volume Plates are designed to increase the functionality of your BioTek microplate spectrophotometer, multi-mode or Hybrid reader by decreasing the sample size required to a mere 2 µL.

This is an exciting platform technology for cell cultivation. It is a highly versatile process which permits great increases in cell and product concentrations as compared to Fed Batch processing.

The QAII Station has been designed to ensure each tested dissolution apparatus conforms with mechanical specifications.

ARTeSYN arterial process valves can be arranged in a multitude of orientations. They can be arranged with individual straight through valves for quick assembly and break down or in multi-valve arrays to facilitate even the lowest hold up volume requirements.

The Avanti® J-HC High Capacity Centrifuge provides you with a complete solution for batch bioprocessing. A maximum of 9 Liters can be spun at speeds of 5,000 rpm and 7,480 x g for greater sample throughput. This allows processing of up to 36 Liters per hour when harvesting bacteria. Enhanced operator safety is provided with disposable HarvestLine System Liners.

The Pyros Kinetix® Flex is an optical tube reader that runs both chromogenic and turbidimetric assays in compliance with the USP, EP, and JP bacterial endotoxin test chapters.

A floor-model preparative ultracentrifuge possessing all of the attributes of the Beckman Coulter entry-level model XE, the Optima XPN enhancements simplifies use, optimizes control and security, and increases productivity.

The ARTeSYN DRV is designed to be a drop in replacement for your existing diaphragm valves, but with an easy to remove and replace flow through liner.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

DOWNSTREAM PROCESSING INDUSTRY NEWS