DOWNSTREAM PROCESSING FEATURED ARTICLES
Tiny Capsule Effectively Kills Cancer Cells
A tiny capsule invented at a UCLA lab could go a long way toward improving cancer treatment.
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![Phenomenex Kinetex Calculator]( "Next-Generation Kinetex Calculator From Phenomenex Customizes Core-Shell HPLC/UHPLC Method Creation")
Next-Generation Kinetex Calculator From Phenomenex Customizes Core-Shell HPLC/UHPLC Method Creation Phenomenex Inc., a global leader in the research and manufacture of advanced technologies for the separation sciences, introduces the next-generation Kinetex Calculator – an online tool that generates customized, optimized Kinetex methods for HPLC or UHPLC systems. -
Rare Cancers Yield Potential Source Of Tumor Growth
Researchers at the National Institutes of Health have discovered a genetic mutation that appears to increase production of red blood cells in tumors.
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Nanotherapeutics Selects GE Healthcare Life Sciences Technologies For Advanced Development And Manufacturing Center
GE Healthcare recently announced that biopharmaceutical company Nanotherapeutics, Inc. has selected GE Healthcare Life Sciences' FlexFactory biomanufacturing platform to perform a central role in its Advanced Development and Manufacturing (NANO-ADM) Center at Alachua, Florida, USA.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Efficiency Test Of ReadyToProcess™ Columns
ReadyToProcess™ columns are prepacked, prequalified, and presanitized process chromatography columns suited for purification of biopharmaceuticals (e.g., proteins, vaccines, plasmids, and viruses) for clinical phase I and II studies. ReadyToProcess columns are available with several media at different volumes (1, 2.5, 10, and 20 L).
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Automation Of A Homogeneous Proximity Assay For Detection Of Residual Protein A In Biological Therapeutics
Protein A is used in affinity chromatography for therapeutic antibody purification and has been shown to leach from columns during purification of antibodies resulting in contamination. Residual Protein A in therapeutic drugs could elicit mitogenic or immunological reactions in patients.
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Optimized Sterile Filtration of Pharmaceutical Solutions
The cost of filtration and separation stages within the production of pharmaceuticals has been increasing along with the increased complexity of final drug products.
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CD69 Expression On Activated Lymphocytes Is Stable In Streck's Cyto-Chex® BCT
The purpose of this study was to determine if the activation marker, CD69, is preserved and stable in whole blood samples collected in Cyto-Chex® BCT. Previous studies have demonstrated CD marker stability of whole blood samples collected in Cyto-Chex BCT for up to 7 days when stored at room temperature (18-22°C). By Jodi Alt, Ph.D
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Metal Removal From Fine Chemical Products
Metal contamination in various injectable or even oral medicines is a serious concern.
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Biomanufacturing Complexity
This white paper addresses one of the most serious challenges facing biomanufacturing professionals today - how to understand and then deal with the extreme complexity associated with biotechnology manufacturing.
DOWNSTREAM PROCESSING PRODUCTS
The ReadyToProcess WAVE 25 rocker features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures up to 25 L. A filter heater is delivered with the system.
DOWNSTREAM PROCESSING MULTIMEDIA
Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.
Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.