DOWNSTREAM PROCESSING FEATURED ARTICLES

virus bacteria The Process Behind The Potential: Therapy For HPV16-Related Malignancies

HPV-related malignancies are poised to skyrocket over the next thirty+ years. Here's a look into Cue Biopharma’s engineering-centric approach to in vivo tumor antigen specific T cell activation to treat these cancers.

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DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

  • Efficiency Test Of ReadyToProcess™ Columns

    ReadyToProcess™ columns are prepacked, prequalified, and presanitized process chromatography columns suited for purification of biopharmaceuticals (e.g., proteins, vaccines, plasmids, and viruses) for clinical phase I and II studies. ReadyToProcess columns are available with several media at different volumes (1, 2.5, 10, and 20 L).

  • Top 10 Considerations When Selecting An Isolator Supplier

    While price is certainly an important reason for buying any piece of capital equipment, it is not always the top reason. There are important considerations to examine when selecting an isolator supplier.

  • Proven Long Life Lasers™ In Optical Particle Counters Optical particle counters (OPC) utilize light illumination and extinction to determine the presence, size, number and/or concentration of particles. Particles are typically suspended in a fluid or air, which flow through the volume that is illuminated and viewed by the detection system.
  • Automated Bioluminescent ADCC Reporter Bioassay Using Bioengineered Jurkat Cells

    Pharmaceutical companies are increasingly exploring new biologic and biosimilar products, and thus increasing monoclonal antibody (mAb) immunotherapeutic research. By Tracy Worzella, Promega Corporation and Brad Larson, Applications Department, BioTek Instruments, Inc.

  • CD69 Expression On Activated Lymphocytes Is Stable In Streck's Cyto-Chex® BCT

    The purpose of this study was to determine if the activation marker, CD69, is preserved and stable in whole blood samples collected in Cyto-Chex® BCT. Previous studies have demonstrated CD marker stability of whole blood samples collected in Cyto-Chex BCT for up to 7 days when stored at room temperature (18-22°C).  By Jodi Alt, Ph.D

  • White Paper: Capillary Electrophoresis — A Simple Technique

    In 1989, Beckman Instruments introduced the first fully automated capillary electrophoresis instrument (P/ACE™ 2000) to the scientific community. At that time, CE demonstrated exceptional resolving of selected compounds, but the new technology lacked a track record of applications. By Beckman Coulter, Inc.

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DOWNSTREAM PROCESSING PRODUCTS

Freeze Drying Formulation Development Services

Freeze drying is a potentially damaging process, especially to labile materials such as proteins or living organisms. Depending on the product type damage can occur at various stages of the process including freezing, drying and heating.

Beckman Coulter Centrifuge: Avanti® JXN Series

High throughput and high productivity are standard fare for every Beckman Coulter centrifuge and the Avanti JXN Series is no exception. It’s more than capable of delivering solutions for shared labs, GMP environments, networked instruments and more.

Gene Expression Wash Buffer Kit
Agilent’s Gene Expression Wash Buffers are optimized and validated for consistently reliable, high volume, post-hybridization processing.
ELx405™ Select Deep Well Microplate Washer
From the leaders in microplate washing, BioTek introduces the world’s first deep well microplate washer that aspirates and dispenses into 96- and 384-well plates ≤50 mm in height.
Benchtop Centrifuge - Allegra X-14
Introducing the new Allegra X-14 Series. At 120 volts, it's a great alternative to the higher voltage Allegra X-15R. This benchtop centrifuge is convenient, hardworking, reliable, and will speed up your process, cycle after cycle.
Beckman Coulter Centrifuge: Allegra® Series General Purpose Centrifuges

High volume labs require simple, durable solutions to their centrifugation needs. Beckman Coulter’s Allegra® Series general purpose, benchtop centrifuges serve the needs of these labs by saving time, offering ease-of-use, and providing reliable design for endurance under the most exacting standards.

Cation Exchange & Anion Exchange Membranes: Natrix® HD Membrane Technology

Natrix HD Membranes offer a breakthrough in membrane architecture that will forever change downstream purification. Available in two chemistries: Q (strong anion exchange) and Sb (strong cation exchange and hydrophobic group).

Single Use Diaphragm Replacement Valve

The ARTeSYN DRV is designed to be a drop in replacement for your existing diaphragm valves, but with an easy to remove and replace flow through liner.

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DOWNSTREAM PROCESSING MULTIMEDIA

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Bioprocess With The Bozenhardts: Filling System Selection

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Optima X Series Ultracentrifuge: Energy Efficient Technology, Real-Time Data Tracker

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

nuviaQS
Nuvia Q & S High Capacity Ion Exchangers For Biotherapeutic Purification Video

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

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DOWNSTREAM PROCESSING INDUSTRY NEWS

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