DOWNSTREAM PROCESSING FEATURED ARTICLES
GE Healthcare Launches FF High Performance Nitrocellulose Membranes Optimized For Diagnostic Assay Reproducibility
GE Healthcare Life Sciences’ new Whatman FF High Performance (HP) membrane provides the industry with a new diagnostic membrane to enable fast, razor-sharp line separation and highly reproducible results for the detection of target molecules in liquids such as water, urine, blood and saliva.
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New LIAISON Ixt/Arrow CellSep Advanced Provides Rapid, Automated Cell Separation For Up To Three Cell Types In A Single Run
DiaSorin has launched LIAISON Ixt/Arrow CellSep Advanced for the automated isolation of cells directly from whole blood or buffy coat.
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3M Launches Large-Scale, Single-Use, Multi-Round Depth Filtration System
3M expanded its portfolio of Encapsulated Zeta Plus™ single-use depth filtration products to include our Model# 16EZC Multi-Round Holder.
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Filming Bacterial Life In Multicolor As A New Diagnostic And Antibiotic Discovery Tool
An international team of scientists led by Indiana University chemist Michael S. VanNieuwenhze and biologist Yves Brun has discovered a revolutionary new method for coloring the cell wall of bacterial cells to determine how they grow, in turn providing a new, much-needed tool for the development of new antibiotics.
DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES
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Automating Protein Purification Processes Achieves Reliable Results And Reproducibility
ÄKTA start is an easy-to-use, reliable protein purification system. In this application note it is described how Erica, a post-doctoral researcher, used ÄKTA start to purify GST-tagged protein using a predefined method template, a GSTrap FF column, and a Frac30 fraction collector.
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A Disposable Valve For Process Chromatography
This case study discusses the need for a fully automated, disposable chromatography system which was PLC controlled and designed for use in a cGMP environment. The required applications for the chromatography system included contamination removal, and concentration and purification of biologically derived proteins used in the production of research and clinical materials.
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Removal Of Host Cell Proteins During Monoclonal Antibody Purification
Protein A chromatography is a widely used and highly successful method of purifying recombinant monoclonal antibodies. However, since Protein A has high affinity for antibodies, harsh conditions such as low pH are often required to elute monoclonal antibodies from Protein A affinity columns. By 3M Purification Inc
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USP <787> Small Volume Testing With Liquid Particle Counters
By their very nature, biological therapeutics are not only expensive to manufacture but are often produced in small volumes.
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Examining Column Reproducibility During Method Development In Clinical Labs
In this study demonstrates how the HSS T3 stationary phase is a reliable stationary phase, as three batches made over a five-year span provide comparable results.
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White Paper: Capillary Electrophoresis — A Simple Technique
In 1989, Beckman Instruments introduced the first fully automated capillary electrophoresis instrument (P/ACE™ 2000) to the scientific community. At that time, CE demonstrated exceptional resolving of selected compounds, but the new technology lacked a track record of applications. By Beckman Coulter, Inc.