DOWNSTREAM PROCESSING FEATURED ARTICLES

Newfound Gene May Help Bacteria Survive In Extreme Environments

In the days following the 2010 Deepwater Horizon oil spill, methane-eating bacteria bloomed in the Gulf of Mexico, feasting on the methane that gushed, along with oil, from the damaged well. The sudden influx of microbes was a scientific curiosity: Prior to the oil spill, scientists had observed relatively few signs of methane-eating microbes in the area. By Jennifer Chu, MIT

DOWNSTREAM PROCESSING WHITE PAPERS & CASE STUDIES

  • Guidelines For Proper Filtration And Delivery Of Samples To On-Line Process Analyzers

    Increasingly precise process control strategies, often linked to computer control, have accelerated the use of sophisticated on-line chemical composition analyzers in plant applications. Instruments such as gas and liquid chromatographs, ion chromatographs, laser optic instruments, atomic absorption instruments and specific ion analyzers, which were rarities in laboratories ten years ago, are now found routinely in plant settings. By Ken Perrotta, Division Engineering Manager

  • Biomanufacturing Complexity

    This white paper addresses one of the most serious challenges facing biomanufacturing professionals today - how to understand and then deal with the extreme complexity associated with biotechnology manufacturing.

  • Met One Sensors Resistant To Vaporous Hydrogen Peroxide (VHP) Pharmaceutical manufacturers often require an aseptic production environment to minimize the presence of microbes and their potential contamination of the manufactured product.
  • Top 10 Considerations When Selecting An Isolator Supplier

    While price is certainly an important reason for buying any piece of capital equipment, it is not always the top reason. There are important considerations to examine when selecting an isolator supplier.

  • Comparing The Automated Pipetting To Volumetric Glassware And Air Displacement Pipettes

    Analytical sample preparation is used in many industries such as forensics, environmental chemistry, mining, beer and wine fermentation and many others. Concentrated samples are diluted and analyzed via High Performance Liquid Chromatography, Gas Chromatography, Atomic Absorption, and/or Inductively Coupled Plasma Spectroscopy to name a few. Traditionally these samples are prepared using volumetric glassware, syringes and/or pipettes.

  • Rapid Screening Of A Cell-Based Assay For GLP-1 Receptor Using A Natural Product Library

    Here we demonstrate the detection of GLP-1R binding through the incorporation of a homogeneous cell-based binding assay using HTRF Tag-lite® technology. By Brad Larson and Peter Banks, BioTek Instruments, Inc. and Nicolas Pierre, Suzanne Graham, Jean-Luc Tardieu, and François Degorce, Cisbio US, Inc.

DOWNSTREAM PROCESSING PRODUCTS

The SPRIworks Fragment Library Systems have built-in size selection and prepare fragment libraries for all three major next generation sequencing platforms. SPRIworks Systems simplify and automate fragment library construction for the Illumina Genome Analyzers, Roche GS FLX DNA Sequencer and Life Technologies SOLiD Sequencers.

Choose from ten fixed volume SoftGrip pipettes covering 0.2 µL to 1 mL. All pipettes have color-coded plunger buttons and labels for easy volume identification.

PRP-X300 is a polymeric column packing for the separation of alcohols and organic acids.

Designed with a smaller footprint so it will fit right in your lab, the Avanti J-E is compact yet powerful. The Avanti J-E’s extensive rotor library maximizes capacity and optimizes g-force for efficient, fast separations and greater variety of applications. Its high-torque, switched reluctance (SR) drive technology delivers faster acceleration and deceleration, which means less wait time for you. It offers an intuitive, user-friendly interface, as well as lower energy costs. What’s more, the Avanti J-E’s low height and contoured front panel help ease the burden of rotor installation and retrieval, for even more convenient operation.

The VHP® TS1000™ Tri-Scale Sensor boosts VHP® VICTORY™ Biodecontamination Cycle efficiency and effectiveness of room and facility biodecontamination ensuring that hydrogen peroxide vapor sterilant is adequately distributed. 

Agilent's GeneSpring GX software provides powerful, accessible statistical tools for fast visualization and analysis of transcriptomics, genomics, proteomics and metabolomics data.
The Avanti J-30I High-Performance Centrifuge System gives you the fastest separations possible - in the shortest amount of time. Swinging-bucket and fixed-angle rotors provide maximum separation forces in excess of 100,000 x g at speeds up to 30,000 rpm.
PreSens offers a new system for measuring oxygen and pH in shake flasks. The SFR – Shake Flask Reader measures rapid and precise in up to 9 shake flasks simultaneously. This novel device is used for microbial cultivations and cell cultures.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

DOWNSTREAM PROCESSING INDUSTRY NEWS