DOWNSTREAM PROCESSING FEATURED ARTICLES

AET BioTech And BioXpress Therapeutics To Co-Develop Biosimilar Adalimumab

AET BioTech, the separate biosimilars business within the generic drug developer AET (Alfred E Tiefenbacher) Group and BioXpress Therapeutics SA, a Swiss-based biotechnology company developing monoclonal antibody (MAb) biosimilars have entered into an agreement for the co-development of a biosimilar version of the TNF inhibitor MAb Adalimumab.

  • Endress+Hauser Introduces OUSBT66 Cell Density Sensor

    Endress+Hauser introduces the OUSBT66 sensor for cell density measurement. Using near-Infrared (NIR) light absorbance technology, the OUSBT66 is a non-intrusive, hygienic sensor that is ideal for real time, in-situ cell production optimization in life science processes, fermentation biomass measurement and algae growth monitoring for biofuel production.

  • Thallion And LFB Terminate Shigamabs Collaboration

    Thallion Pharmaceuticals Inc. (TSX-V: TLN) ("Thallion") and LFB Biotechnologies ("LFB") today announced that they have reached an agreement on the termination of their Development and Licensing Agreement related to Thallion's Shigamabs® program.

  • Forsyth Scientists Define The Bacteria That Live In The Mouth, Throat, And Gut

    For the first time, scientists have defined the bacteria that inhabit multiple sites along the healthy human digestive tract in a large number of individuals. To prevent and control bacterial diseases, it is essential to first identify which bacteria are responsible for keeping us in good health.

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DOWNSTREAM PROCESSING PRODUCTS

Sartopure PP2 Cartridges were optimized for the wide range of prefiltration.

Resin are designed specifically for intermediate purification steps that remove host-cell contaminants from partially purified targets using strong or weak hydrophobic interactions. Methacrylate-based beads for protein and nucleic acid purification using hydrophobic interactions are available for purifying compounds that have weak or strong hydrophobic regions.

Polyethylene (PE) and PTFE hydrophobic membranes for economical air / gas and vent filtration. Virus, bacteria and spore retentive. PE is gamma stable and will substitute PVDF. Retention ratings from 0.01um in gas applications or 0.1um in liquid applications, to 10um.

PES, Nylon or Cellulose Acetate hydrophilic membranes provide performance improvements over other membrane types like PVDF. Microbially retentive micron ratings from 0.04um, 0.1um and 0.2um to prefilter ratings 0.45um, 0.65um and up to 1.2um.

ZenPure designs, mold-manufactures and injects its own filter components. Engineering, product development and filter production under ISO standards facilitate full quality audit and traceability to meet the highest industry standards. Validation support documentation is available for appropriate products.

A proven method for confirming protein purity and yield without the need for gel staining steps. Stain-free gels provide visual confirmation of protein purity and yield by gel electrophoresis in less than 30 minutes. Stain-free technology is perfect for drug discovery, drug development, and method development for preclinical research.

The VHP® TS1000™ Tri-Scale Sensor boosts VHP® VICTORY™ Biodecontamination Cycle efficiency and effectiveness of room and facility biodecontamination ensuring that hydrogen peroxide vapor sterilant is adequately distributed. 

Capto L is an affinity chromatography medium for the process-scale capture of a broad range of antibodies and antibody fragments.

ARIES™ Smart Balance Rotor automatically corrects for imbalance.

The Agilent 2100 Bioanalyzer is a microfluidics-based platform for sizing, quantification and quality control of DNA, RNA, proteins and cells on a single platform. Results are delivered within 30-40 minutes in automated, high quality digital data.

DOWNSTREAM PROCESSING MULTIMEDIA

Bioprocess With The Bozenhardts is back, with a fresh episode packed with advice from Herman and Erich on the selection of filling systems for biopharmas. Listen in as the Bozenhardts give us an update on the process, logistics, and administration trends that are informing filling system decisions today, and offer direction on making choices that will prepare you for the fast-advancing therapies of tomorrow.

Beckman Coulter's Randall Lockner, marketing manager for centrifugation, explains the highlights of the floor model ultracentrifuge, the Optima X Series.

Bio-Rad now offers two very high capacity ion exchangers: Nuvia S, which can be used for capture and/or intermediate polishing; and Nuvia Q, which can be used for intermediate and/or final polishing.

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