Downstream Processing Products

1. Disposable Conical Transfer Sleeve 2/2/2012

   Another proven method for cGMP processing is also available now using drums, a conical drum funnel and drum lifts.

2. Mineral Membranes & Systems: Kerasep®- Bio Membranes and Systems 8/23/2011
   Cross- Flow Filtration mineral (inorganic) membranes and systems for bioprocessing and separation of biomolecules (e.g. monoclonal antibodies); especially for UF/DF filtration step in downstream processing.
3. Beckman Coulter Centrifuge: Avanti® J6-MI 12/4/2015

   It spins volumes.

   With six-liter capacity and an innovative range of rotors, carriers, and adapters, this versatile centrifuge can handle multiple high capacity applications. Ideal for bioprocessing and clinical and blood sample preparation, the J6-MI is the standard for quiet and convenient operation.

4. Bio-Beads SM-2 Adsorbents 5/17/2013

   Bio-Beads SM-2 nonpolar polystyrene adsorbents are analytical grade, neutral macroporous polymeric beads for use in hydrophobic interaction chromatography.

5. ReadyToProcess WAVE™ 25 Bioreactor System 2/24/2025

   The ReadyToProcess WAVE 25 rocker features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures up to 25 L. A filter heater is delivered with the system.

6. Emphaze™ AEX Hybrid Purifier 7/9/2014

   The Emphaze Hybrid Purifier is a new single-use clarifying device containing a multi-mechanism all synthetic Q-functional anion exchange media integrated with a fine particle, bioburden reduction membrane. The anion exchange media is comprised of a quaternary amine hydrogel supported by a fine fiber nonwoven scaffold. A combination of 3M technology platforms enables the hyperfunctionalization of a high purity polypropylene nonwoven with a covalently attached, thermally stable, water soluble polymer; the functional polymer accounts for roughly two-thirds of the mass of the anion exchange media. The bioburden reduction membrane is a highly asymmetric, high loading capacity polyamide membrane which has nine zones of decreasing pore size spanning a roughly 20X range and terminating with a 0.2 μm bioburden reduction rated pore size.

7. Nuvia Q Anion Exchange Media 6/6/2011
   Nuvia media are a family of ultra high capacity ion exchangers designed for optimal performance in bioprocessing workflows.
8. Process Development And Scale-Up Of Ceramic Hydroxyapatite 9/29/2016

   CHT is a leading purification medium of biomolecules in today’s demanding downstream process industry. Its mixed-mode support offers unique selectivities and often separates biomolecules that appear homogeneous with other chromatographic methods. The diverse binding capabilities of CHT for host cell proteins, leached protein A, antibody dimers and aggregates, nucleic acids, and viruses allow its use at any stage from initial capture to final polishing.

9. Anti Iba1, Polyclonal Antibody, Rabbit 6/1/2011
   Antibody against Macrophage/Macroglia-specific Protein, Iba1.
10. Perfusion & Concentrated Perfusion Technology 6/29/2011
    Recirculating hollow fiber systems have been used for a long time with mixed results. The recurring problem with these and all other cell retention systems is the difficulty in scaling up and staying sterile.