Downstream Processing Featured Articles

1. Revision Of The EU GMP Guide: EU Commission Publishes Proposals For Chapters 3, 5, 6 And 8 1/24/2013

   On 17 January 2013, the EU Commission published the drafts of 4 revised chapters of the EU GMP Guide. The publication had been expected for a long time now.

2. 'Patch on a Chip' under development by Axon Instruments 11/1/2000
   New fabrication method will allow thousands of simultaneous patch clamp recordings...
3. Launch Of A New Protein A Chromatography Resin For Purification Of Antibody Drugs 10/2/2012

   Kaneka Corporation (Osaka, Japan; President: Kimikazu Sugawara ) announces the launch of KANEKA KanCapA, a new Protein A Chromatography Resin for the purification of therapeutic antibodies. 'KANEKA KanCapA' exhibits high antibody adsorbing capacity and alkaline resistance.

4. Cancer Cell Article Demonstrates First Definitive Evidence For Targeting of Pol I As New Approach To Cancer Therapy 7/10/2012

   Cylene Pharmaceuticals today announced that research collaborators at the Peter MacCallum Cancer Centre (Peter Mac) in Melbourne, Australia have established, for the first time, that RNA Polymerase I (Pol I) activity is essential for cancer cell survival and that its inhibition selectively activates p53 to kill tumors.

    

5. Brooks' Single-Use REMP Tubes Support Optimization Of Automated Serum And Plasma Storage 9/12/2012

   Brooks Life Science Systems, a division of Brooks Automation, Inc. a leading worldwide provider of automation solutions for compound and biological sample storage and management, announced recently that Karolinska Institute Biobank (KI Biobank) is successfully using Brooks’ REMP single-use heat sealed sample tubes to secure the long-term storage of plasma, serum and urine samples in its automated biorepositories.

6. The Medicines Company And Bristol-Myers Squibb Begin Global Alliance For Recothrom® 2/8/2013

   The Medicines Company (NASDAQ: MDCO) announced today that the global license and two-year collaboration for Recothrom®, a recombinant thrombin approved by the U.S.

7. HPV Vaccine May Benefit HIV-Infected Women 11/8/2012

   Women with HIV may benefit from a vaccine for human papillomavirus (HPV), despite having already been exposed to HPV, a study finds. Although many may have been exposed to less serious forms of HPV, more than 45 percent of sexually active young women who have acquired HIV appear never to have been exposed to the most common high-risk forms of HPV, according to the study from a National Institutes of Health research network.

8. Tweaking Gene Expression To Repair Lungs 2/25/2013

   Lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are on the rise, according to the American Lung Association and the National Institutes of Health.

9. Scientists Show Protein-Making Machinery Can Switch Gears With A Small Structural Change 11/15/2012

   For the past several years, Min Guo, an assistant professor at The Scripps Research Institute (TSRI), has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins.

10. Crucell And Scripps Research Discover And Describe Broad-Spectrum Antibodies Against Influenza B, A Crucial Link In Development Of Universal Flu Therapies And Vaccine 8/9/2012

    In a landmark discovery, researchers from Crucell Holland B.V. and The Scripps Research Institute, recently announced the identification of the first human monoclonal antibodies that appear capable of disabling all influenza B viruses.