Single Use Featured Articles

  1. White Paper: Silicone Molded Tubing Assemblies: A Solution For Reduced Contamination Risk And Greater Efficiency 1/13/2009
    The adoption of single-use systems is one of today’s most noteworthy trends in biopharmaceutical processing. The next-generation solution, molded tubing assemblies made of silicone, can help reduce the risk of contamination in biopharmaceutical and pharmaceutical processing. By Roger Hendrick, Audrey Wipret
  2. Case Study: mAb Purification - BioSC™ Sequential Multi Column Chromatography 12/23/2008
    A comparative COG’s (Cost of Goods) study for a batch and SMCC mAb capture step using Protein A media clearly demonstrates the enhanced productivity and economic savings that are achievable using BioSC by Novasep technology. A production-scale batch process might use a 1.7 meter column with a 20 cm bed height and a working capacity of 20 g/L mAb per liter of media running at 300 cm/h.
  3. Article: Method For Evaluating Bio-Container Transportation Applications 12/22/2008
    Single-use components are finding more use in the biopharmaceutical industry. One application increasing in use is transportation of sterile liquids. There are many challenges to consider when shipping a flexible container with sterile liquids. By Charter Medical
  4. Performance Evaluation Of An Automated Bioreactor Sampling System For Mammalian Cell Cultivation 11/4/2008
    Two common goals of biotherapeutics development are reduction in timelines and increased process understanding. An automated bioreactor sampling system developed by Groton Biosystems has proven its capacity to address those two seemingly conflicting needs for the industry. Due to the extreme length and stringent sterility requirement of mammalian cell cultivation, sampling automation of mammalian bioreactors remains an unmet need. By Groton Biosystems
  5. White Paper: Performance Evaluation Of An Automated Bioreactor Sampling System For Mammalian Cell Cultivation 11/4/2008
    Two common goals of biotherapeutics development are reduction in timelines and increased process understanding. An automated bioreactor sampling system developed by Groton Biosystems has proven its capacity to address those two seemingly conflicting needs for the industry. Due to the extreme length and stringent sterility requirement of mammalian cell cultivation, sampling automation of mammalian bioreactors remains an unmet need. By Groton Biosystems
  6. Case Study: IND-Enabling Studies And Chemical Synthesis Completed — Nine Months From Lead Selection 10/1/2008
    A client asked Ricerca to develop a robust chemical process, complete GLP toxicology to support a major program, and file an IND — all on a very aggressive timeline. By Ricerca Biosciences, LLC
  7. IND-Enabling Studies And Chemical Synthesis Completed — Nine Months From Lead Selection 10/1/2008
    A client asked Ricerca to develop a robust chemical process, complete GLP toxicology to support a major program, and file an IND — all on a very aggressive timeline. By Ricerca Biosciences, LLC
  8. Finding The Right Contract Manufacturer 8/18/2008
    Finding a suitable contract manufacturer is, perhaps, one of the most viable options. The pharmaceutical company can concentrate effort and money on research and development and marketing, while the contract manufacturer takes care of the manufacturing process, including validation, support for license application and packaging. In addition, outsourcing can be scheduled into the strategic planning of a drug’s lifecycle. During the early development phases, which last years, a partner with the necessary facilities and experience can be sought out and brought onboard. By Vetter Pharma-Fertigung GmbH & Co. KG
  9. Article: Comparing Shaker Flasks With A Single-Use Bioreactor For Growing Yeast Seed Cultures 2/13/2008
    Pichia pastoris is a species of methylotrophic yeast that is widely used for protein expression both in academia and the biotechnology industry. A number of properties make it suited for this task. Pichia has a high growth rate, and it can grow on simple, inexpensive media. It can also be grown in either shaker flasks or bioreactors, which makes it suitable for both small- and large-scale protein production
  10. The Future Of BioManufacturing

    The biomanufacturing industry is undergoing a major shift, from single-product processes and stainless steel infrastructure to flexible, multi-product facilities using single-use technology.