Single Use Featured Articles

31. High-Flow Sterile Connectors For Single-Use Applications

    Over the past decade, two developments have increased demand for high fl ow-rate connectors: Size advances in single-use bioreactors up to 2000L and the  implementation of single-use downstream.

32. The Benefits of Single-Use Technology in R&D and Manufacturing - Infographic

    This infographic represents how to bridge the gap in automated single-use technology between R&D and manufacturing, and the benefits of using single-use technology.

33. Article: Increase Production Efficiencies With Single-Use Transfer Lines

    Biopharmaceutical manufacturers are implementing new ways to leverage existing plant infrastructure to enhance process reliability and flexibility. One solution that continues to gain momentum is single-use systems — particularly single-use transfer lines — which can deliver significant value through added flexibility, improved asset/equipment utilization, and increased cost savings.

34. Article: Providing Sterility Assurance Between Single-Use And Stainless Systems

    As numerous biopharmaceutical manufacturers have gained firsthand experience with the benefits of incorporating single-use systems into their facilities, they are looking to expand use in both up-stream and down-stream applications. This is no surprise as increased volume and diversity of pharmaceutical products is causing manufacturers to design their facilities based on shorter production runs with multiple changeovers. Meeting these demands requires operational flexibility. By John Boehm and Brent Bushnell

35. Continuous Biomanufacturing: 10 Reasons Sponsors Hesitate

    The industry is abuzz with talk about continuous biomanufacturing (CB), and its virtues have been well described. Here we will look at some of the barriers or concerns perceived to limit its value to the industry. Justified or not, quite a few concerns have been expressed regarding the implementation of this new, rather disruptive technology. 

36. Combination Sterile Connections For Single-Use Applications

    Gain insight into why combination connections are used in single-use bioprocessing and guidance on how single-use systems can be designed to integrate the combination connectors.

37. Genderless Sterile Connectors Offer Flexibility And Faster Changeovers

    Genderless sterile connectors — with their ability to interconnect with each other without male/female limitations — can enhance the flexibility of single-use systems in a range of bioprocessing applications.

38. The Benefits Of Genderless Sterile Connectors For Single-Use Applications

    Genderless connections are those in which the connector halves are identical in design, thus eliminating the need for different male and female halves to make the connection.

39. Article: How To Choose An Industrial Cation Exchanger For IgG Purification

    Cation-exchange chromatography is the third most used industrial method for antibody purification after anion-exchange and protein A affinity chromatography. It is most commonly used as an intermediate step but continues to attract attention as a capture method. By Pete Gagnon