Case Study: mAb Purification - BioSC™ Sequential Multi Column Chromatography
Source: Novasep
A comparative COG's (Cost of Goods) study for a batch and SMCC mAb capture step using
Protein A media clearly demonstrates the enhanced productivity and economic savings that are
achievable using BioSC by Novasep technology. A production-scale batch process might use a
1.7 meter column with a 20 cm bed height and a working capacity of 20 g/L mAb per liter of media running at
300 cm/h.
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