Insights On Downstream Manufacturing

  1. Real-Time Monitoring Of Solvent Clearance By TFF In The ADC Process 6/13/2025

    Raman spectroscopy revolutionizes ADC manufacturing by enabling real-time monitoring of solvent clearance. Discover how it enhances process control, ensures regulatory compliance, and supports the production of high-quality therapeutics.

  2. Minimizing Fluid Loss By Monitoring Back Pressure During Clarification 6/12/2025

    Learn how a biopharma manufacturer mitigated the significant financial risk of fluid loss with a pressure-sensing pump that now protects their high-value product during clarification operations.

  3. Seals And Stability: Preventing Failures In Synthesis And Chromatography Columns 6/11/2025

    Unlock the key to long-term column performance and stability. Learn how crucial seal maintenance can prevent catastrophic failures and safeguard your therapeutic products.

  4. Evaluation Of A New Multimodal Anion Exchange Resin For Emerging Biotherapeutic Process Challenges 6/11/2025

    Tackle tough bioseparation challenges head-on. Learn about a new multimodal anion exchange resin, showcasing superior impurity clearance and higher yields for complex and low pI proteins.

  5. Advancing The Purification Of VSV-G Pseudotyped Lentiviral Vector 6/9/2025

    Discover new strategies to overcome lentiviral purification challenges with a scalable approach that maintains viral infectivity through gentle processing conditions.

  6. AAV Purification: Solving Downstream Challenges 6/9/2025

    In this roundtable discussion, a trio of distinguished experts in AAV purification and process development share their expertise and best practices in tackling and solving downstream challenges.

  7. Exploring The Challenges Of Cell Dissociation In Vaccine Manufacturing 6/9/2025

    Vaccine manufacturing relies on efficient cell dissociation methods. Explore the challenges of traditional approaches like trypsin and the benefits of animal origin-free alternatives for improved workflows.

  8. Utilizing Small-Scale Downstream Studies Across Biologics Manufacturing 6/6/2025

    Small-scale downstream studies play a critical role in enabling efficient, low-risk tech transfer for biologics development.

  9. The Hidden Threat To Product Purity: Neglected Seals In Synthesis Columns 6/3/2025

    In biopharmaceutical manufacturing, seemingly minor components like seals can pose significant risks to product purity. Overlooking them can lead to contamination and costly delays.

  10. Innovations In CGT Processing 6/3/2025

    Discover insights into how innovative connectors streamline workflows, save time, and enhance reliability in critical applications, ultimately supporting improved outcomes in cell and gene therapies.