Insights On Downstream Manufacturing

  1. Single-Step Purification Of A 21-mer Oligonucleotide Using Capto™ Q ImpRes Resin 1/13/2025

    Explore how the oligonucleotide therapeutics market is advancing with scalable solutions for high-purity purification, supporting global production of life-changing RNA therapies.

  2. Effect Of NK-EVs And Carboplatin On Osimertinib-Resistant Lung Cancer Cells 12/18/2024

    Delve into a study that examines the possibility of the combination of NK-cell-derived EVs and CBP as a viable immunochemotherapeutic strategy for resistant cancers.

  3. mAb Up- And Downstream Process Intensification Strategies 12/12/2024

    Discover how to reduce monoclonal antibody (mAb) manufacturing time and costs through process intensification. Learn about continuous perfusion, ultrahigh cell density banks, and more.

  4. mRNA Purification Using Anion Exchange Chromatography At Ambient Temperature 12/11/2024

    Explore how anion exchange chromatography with dual gradient elution enables efficient mRNA purification at ambient temperature.

  5. Best Practices For Chromatography Column Packing 12/6/2024

    Proper packing for resin is crucial to prevent issues like cracking or channeling which can lead to process disruptions and product loss.

  6. Packing MabSelect™ And MabSelect SuRe™ Resins Using Verified Methods 12/6/2024

    Proper packing of MabSelect resins is crucial for efficient chromatography. Verified methods ensure stability, optimal flow, and reproducibility across scales using automated tools.

  7. Guide To PUPSIT And Annex 1 In Aseptic Processing 12/5/2024

    Pre-use, post-sterilization integrity testing (PUPSIT) ensures filters remain undamaged and effective during aseptic manufacturing. Discover how you can successfully perform PUPSIT with proven solutions.

  8. Resolute® BioSMB Multi-Column Chromatography 12/2/2024

    Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

  9. Intensifying Chromatography With A Scalable Sartorius Rapid Cycling Platform 11/27/2024

    Explore the capabilities of two new chromatography systems that meet key requirements for rapid cycling chromatography (RCC) and enhance performance for membrane-based ion exchange.

  10. Leveraging Protein A Capture Technology 11/27/2024

    See how a Protein A capture technology boosts mAb purification productivity 10-fold, supports membrane-based platforms, and enables intensified processes with improved yields.