The Case For Modernizing Small-Volume Aseptic Processing

By Nik Ekman, application development manager, cell & gene therapy, CPC

Maintaining sterility for therapeutics that biopharmaceutical and cell and gene manufacturers produce is critical – particularly when unique, personalized samples are processed for precision medicine. As precision medicine grows, so does the demand for greater efficiencies in smaller batch aseptic manufacturing. ​

Nik Ekman, Application Development Manager at CPC, makes the case for moving outside of the biosafety cabinet. The white paper focuses on: ​

Cost: eliminating tube welder costs (~$20-45K per welder) and associated consumables like blades and adapters (~$7-$20 per weld) + validation, calibration, maintenance, and repair.​

Time, efficiency and operator use: Reducing the time required to make sterile connections. Making a sterile connection with MicroCNX Series Connectors is 4-7X faster than an operator using a tube welder.​

Flexibility: MicroCNX connectors also can connect tubing of different materials and sizes without adapters, unlike welders. ​

Reducing hold up volume: connectors do not require the extra tubing that is involved in tube welding, which is a source of hold up volume.