ADC Purification Without Compromise

Antibody drug conjugate (ADC) manufacturing presents unique challenges—from operator safety to process consistency. Repligen’s KrosFlo® RS 10 RPM™ tangential flow filtration (TFF) system is designed to address these complexities head-on. This overview explores how the system enables end-to-end automation and remote operation within isolators, helping reduce exposure to cytotoxins and minimize process delays. With integrated real-time drug-antibody ratio (DAR) measurement capabilities, operators gain greater control over product quality and batch consistency. The system’s design prioritizes both efficiency and safety, making it a powerful tool for accelerating ADC production timelines.

Watch the video to see how the RS 10 RPM™ system supports high-yield, high-precision workflows in ADC manufacturing.