Insights On Downstream Manufacturing
-
A Closed And Automated Solution To Streamline Your Workflow
3/27/2024
Whether it's dilution, mixing, cryopreparation, or splitting of cellular products, ReadySelect offers a comprehensive solution for your up- or downstream cell therapy manufacturing workflow.
-
Top Challenges In Recombinant Protein Purification Process Development
3/27/2024
Get insights from process developers working with recombinant proteins that cannot be purified with affinity chromatography.
-
Understanding Viral Clearance During Anion-Exchange Chromatography
3/26/2024
A design of experiments (DoE) study examined the anion-exchange process in general and to draw possible correlations between such properties and overall viral clearance capability.
-
Scalable mRNA Affinity Capture
3/26/2024
The POROS Oligo dT(25) affinity resin offers a solution for the purification of mRNA by providing efficient purification, high binding capacity, and selectivity, while removing impurities.
-
Gain Confidence In Your ADCs With Stability Prediction Experiments
3/26/2024
Learn more about the importance of stability experiments early in the development process for antibody drug conjugates (ADCs) with the data collected being used to mitigate stability problems during extended storage or high-concentration use of the ADC.
-
Monoclonal Antibody Aggregate Polish And Viral Clearance Using HIC
3/26/2024
Explore highly productive POROS HIC polishing processes in both bind–elute and flowthrough modes that outcompeted legacy clinical processes designed for two highly challenging case studies (MAbs A and B).
-
AAV Process Intensification Using High Salt Lysis And Salt Tolerant Endonuclease
3/25/2024
In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity.
-
Get Full Control Of Your T Cell Isolation
3/21/2024
This study demonstrates the automated magnetic isolation of CD4/CD8+ cells from fresh or frozen leukapheresis using a functionally closed cell processing system paired with a modular application.
-
The Increasing Demand For Sterile Filtration Of High Concentration Drugs
3/21/2024
Explore the current trends and challenges with manufacturing high-concentration drug products and an approach to performing extensive filterability trials without a high quantity of expensive product.
-
What Is The DynaChromâ„¢ Single-Use Chromatography System?
3/21/2024
This chromatography system offers a flexible solution, paired with an advanced software platform, allowing easy integration with downstream process automation.