Insights On Downstream Manufacturing

  1. mAb Purification: A Two-Step Approach Using A Strong AEX-HIC Mixed-Mode Resin 11/24/2025

    Elevate your mAb purification with a two-step chromatography strategy. Simplify the process, eliminate an entire step, and achieve substantial savings in time and material costs.

  2. Chromatography In Biologics Manufacturing: Purification Science, Resin Applications, And System Qualification 11/24/2025

    Explore chromatography fundamentals, resin selection strategies, and the regulatory frameworks required to qualify automated systems for compliant, commercial-scale biologics manufacturing.

  3. Rapid Process Development For Cell Line Optimization Using Protein A 11/20/2025

    Rapidly purify 24 monoclonal antibody samples in under eight hours with a membrane-based affinity capture that streamlines cell line optimization and accelerates early-stage bioprocess development.

  4. End-To-End Solutions For Biopharma Bottles 11/18/2025

    Until recently, only isolated solutions for working filling, freezing/thawing and transporting sensitive drug materials were available. Learn how we've addressed this problem with end-to-end bottle solutions.

  5. Virus Retention Performance Under Diverse Processing Conditions 11/14/2025

    Virus filtration is robust across a wide range of process parameters, including high protein concentration and flow decay. Discover how retention relies on size exclusion to simplify risk assessment.

  6. Accelerating Early Phase Biologics From The Clinic To Commercialization 11/13/2025

    Strategic planning in early-phase biologics accelerates clinical progress, reduces risk, and lays the groundwork for scalable, compliant manufacturing and successful commercialization.

  7. Cell Culture Media Mixing In A Benchtop Single-Use Mixer 11/13/2025

    Explore how efficient powder-liquid mixing and sterile filtration preserve media integrity and support reproducibility in biopharmaceutical workflows, with promising scalability for larger-volume applications.

  8. Quality Control In IVT RNA Workflow 11/12/2025

    Accurate sizing and purity checks are essential in IVT RNA workflows. Explore how automated electrophoresis improves QC efficiency and ensures RNA integrity for downstream applications.

  9. Biopharma Supply, Reimagined: Blarney, A Climate-Neutral Facility For Best-In-Class Filters 11/11/2025

    Explore how a new, climate-neutral manufacturing facility strengthens biopharma supply chains. Understand the benefits of its advanced filtration technologies and commitment to environmental sustainability.

  10. High Capacity, Scalable Cation Exchange Chromatography Membrane For Purification Of Monoclonal Antibody 11/11/2025

    Overcome binding capacity limitations in mAb purification. A new hydrogel membrane enhances productivity 30x over resins, offering superior loading capacity and consistent, scalable impurity removal.