Cytiva product datasheets, catalogs, app notes

41. Process-Economy Simulation Of mAb Capture Step With Protein A Chromatography Resin 10/10/2018

    Calculation examples that highlight scenarios where the enhanced capacity and alkaline‑stability of MabSelect PrismA can provide process economic benefits to large‑scale mAb processing.

42. Use Of Sodium Hydroxide For Cleaning And Sanitization Of Chromatography Resins And Systems 10/2/2018

    This application note examines these aspects of using sodium hydroxide as a cleaning and sanitizing agent.

43. Capacity And Performance Of MabSelect™ PrismA Protein A Chromatography Resin 10/2/2018

    This application note demonstrates the binding capacity of MabSelect PrismA in comparison with its predecessor products for both polyclonal and monoclonal antibodies.

44. Downstream Process Development For Efficient Purification Of Adenovirus 9/10/2018

    Here, we describe the development of two effective downstream processes for purification of adenovirus from cell culture harvest.

45. Optimization Of Midstream Cell Lysis And Virus Filtration Steps In An Adenovirus Purification Process 9/10/2018

    Here we describe screening of detergents for release of adenovirus from HEK293 host cells to replace the traditionally used detergent Triton™.

46. Process Economy Of Using Cytodex Gamma Microcarriers 8/3/2018

    Microcarriers are commonly used in bioreactor cultures to provide a large growth surface for anchorage-dependent cells, and are typically provided either untreated or gamma-irradiated and ready for use.

47. Accelerated Manufacturing Of Subunit Vaccines For A Rapid Pandemic Response 8/3/2018

    This application note describes a process for rapid production of recombinant anthrax protective antigen (rPA) in short process time for the manufacture of an anthrax subunit vaccine.

48. Efficient Purification Of The Pertussis Antigens Toxin, Filamentous Haemagglutinin, And Pertactin In Chromatography Workflows 2/21/2018

    Read how this method resulted in higher purity and yield than what can be expected from a purification process based on salt precipitations and sucrose gradient centrifugation.

49. Automated In-Line Buffer Prep Saves Time And Facility Footprint 2/1/2018

    Buffer preparation is both time- and space-consuming and become a challenge in biomanufacturing. This application note describes a lean approach to buffer preparation by implementing in-line conditioning.

50. Continuous Chromatography In Downstream Processing Of A mAb 2/1/2018

    In this study, periodic counter current (PCC) chromatography and straight-through processing (STP) technologies were evaluated in a continuous three-step monoclonal antibody (mAb) purification process.