Cytiva product datasheets, catalogs, app notes

  1. Executing A Closed Connected Process From Start To Finish 12/22/2020

    Review recommendations from the execution of a closed and connected mAb process, from design considerations to scale-up.

  2. A Model To Increase Yield In mAb Cell Culture Perfusion At Large Scale 9/28/2020

    As process intensification is adopted into large scale manufacturing, the responsibility of scale-down models to accurately represent the expanded operating space quickly follows. 

  3. Developing A Closed Connected Single Use mAb Purification Process 9/28/2020

    This article provides an overview of a successfully designed closed and physically connected mAb process at the pilot scale with single-use components.

  4. Developing A Continuous Large-Scale Perfusion Cell Culture Process 9/25/2020

    The key benefits of perfusion processes are compact process design, flexibility, increased productivity, increased yield, and consistent product quality. 

  5. Automated High Throughput mAb Purification Using Fibro Technology 4/21/2020

    Read how the Fibro PrismA unit provides a time advantage with comparable recovery and product quality attributes to resin-based column.

  6. Scale-Up Of CHO Cell Fed-Batch Cultures 2/21/2020

    This application note compares cell growth and recombinant protein production of multiple CHO cell clones when cultured in HyClone ActiPro basal medium and Cell Boost 7a and 7b feeding supplements.

  7. Effects Of Feeding Strategy On CHO Cell Performance In Fed-Batch Cultures 2/21/2020

    Here, we demonstrate a fed-batch process for a CHO cell line producing a mAb. The results emphasize the importance of an appropriate feeding strategy to optimize cell growth and productivity.

  8. Purifying Tagged Proteins Using A Small And Compact LC System 2/3/2020

    Learn how you can perform routine protein purification in a variety of common applications with ease while efficiently utilizing bench and cold cabinet space with the ÄKTA go.

  9. Epitope Binning: A Critical Step In Antibody Selection 1/31/2020

    Epitope binning immunoassays using surface plasmon resonance (SPR) can and should be deployed in the development of new potential drug candidates. This article discusses how SPR is used to characterize closely related “bins” of mAbs targeting the same epitope of the target protein and how the selection process is used to develop new vaccines, therapeutic antibodies, and diagnostic tools.

  10. EDGE Confocal Imaging Technology 10/9/2019

    Increasingly, scientists are being challenged to study more biologically-relevant model systems, and this often means imaging thick, demanding 3D samples that may also be alive. Read how IRIS and EDGE confocal imaging can offer high contrast imaging of thicker samples.