Culture Development White Papers and Case Studies

11. Multi-Parallel Microscale Bioreactor System Unlocks Bottlenecks In Bioprocess Development 9/13/2012

    Implementation of high throughput automated systems is recognized as a valuable approach in the field of bioprocess development. An efficient multi-parallel microscale bioreactor system can unlock development bottlenecks in a variety of bioprocess applications, such as cell line screening, media development, feed and process optimisation, QbD and DoE studies.

12. 5 Challenges That Continue To Plague The $2B Pharmacovigilance Sector 6/15/2012

    The Asia Pacific region is fast becoming the growth center of the worldwide pharmaceuticals market. By 2015, these markets are projected to account for almost a third of the total pharmaceutical sales worldwide. By Pharma IQ

13. Automation Of A Novel Cell-Based ELISA For Cell Signaling Pathway Analysis 5/21/2012

    Monitoring and quantifying cell signaling pathways is critical for understanding the behavior of cell processes and many disease states. By Wendy Goodrich and Peter Banks, BioTek Instruments, Inc., Winooski, VT and Ron Osmond and Antony Sheehan, TGR Biosciences, Adelaide, Australia

14. Managing Cell-Based Potency Assays: From Development To Lifecycle Maintenance 4/24/2012

    Characterization of a biological product — which includes the determination of physicochemical properties, biological activity, immunochemical properties, purity and impurities — is necessary to establish the safety and efficacy profile of a given product (ICH Q6B).  By Dr. Weihong Wang, manager, Molecular and Cell Biology, Eurofins Lancaster Laboratories

15. Decontamination Of Laboratory Animal Research Rooms Using Vaporized Hydrogen Peroxide (VHP®) 4/12/2012
    Walter Reed Army Institute for Research is a U. S. government laboratory facility located in the Washington D.C. area.
16. Propagation Of Influenza Virus In Vero Cells 2/9/2012

    The aim of this work was to establish a process to produce influenza virus in Vero cell culture using single-use equipment. The end result would be a fast and simple process enabling scale-up and adaptation to industrial production. The following parameters were evaluated: medium composition, cell detachment, medium supplements, agitation conditions, and infection conditions. 

17. Biomanufacturing Flexibility 12/22/2011

    This white paper from BIO-G looks at how to create flexible, agile manufacturing facilities to respond to the current glut of biomanufacturing capacity and industry consolidation. Future proofing these facilities for higher titers and multiple product lines is also explored.

18. Chromatography Column Protection With 3M Purification LifeASSURE™ PLA Series Membrane Filters 9/14/2011
    Protective, or guard, filters are often used in chromatography column purification steps to protect the column media from contaminants in the various fluids that come in contact with the column.
19. Development Of A Partly Controllable System At Shake Flask Scale 9/2/2011
    The main objective of this study was to develop an easy to handle and partly controllable process cultivation system at shake flask scale.
20. Automated Washing Of Multiplex Bead Based Assays For The Luminex MAGPIX® Reader System 8/22/2011
    Luminex xMAP® technology provides the means to measure multiple analytes simultaneously from the same sample. By Paul Held Ph.D., Laboratory Manager, Applications Dept., BioTek Instruments, Inc.