Culture Development White Papers and Case Studies

  1. The Role Of Biological Indicators For Hydrogen Peroxide Vapor Technology

    Biological indicators (BIs) have become the industry standard for verification of hydrogen peroxide vapor (HPV) decontamination efficacy. By Dr Lynne Murdoch, Bioquell UK Ltd

  2. Supply Chain Reacts To Health Care Cost Pressures With Innovative Partnerships

    Innovation defines a wide range of initiatives that supply chain leaders in life science companies are pursuing to best help their organizations meet the fundamental changes occurring in the industry….heightened regulatory enforcement, outcomes-based reimbursement, consumer vs. provider centric care, increased access to care, and new taxes.  The magnitude of these changes was made perfectly clear at a Health Care conference hosted by Gartner in November 2012.  The keynote speaker, Don Cassey, CEO, Medical Segment, Cardinal Health, declared that the health care industry must reduce its cost by 30% in order to remain sustainable.  To put this in perspective, this means that the US health care system would need to shed $5Trillion in operating cost.  The need and value of step change innovation in the health care industry will never be higher.  By Dave Bode, VP, Health Care Solutions – DSC Logistics

  3. A Strategy For Implementing Rapid Microbial Methods

    The purpose of this white paper is to present a strategy to be used and applied for rapid microbiological methods (RMM). By Gilberto Dalmaso, Sterility Assurance Consulting, A&L Co

  4. Human ADME & Studies With Radiolabeled Compounds

    During clinical drug development there can be several situations where the use of radiolabeled medication or other radiolabeled compounds is required or favorable to accomplish the study objectives. This whitepaper is mainly focusing on human ADME studies and “microdose” studies to assess absolute bioavailability (BA). The major part of the information in this overview is also relevant for other clinical studies with a radiolabeled compound. By Ad Roffel and Henk Poelman, PRA Health Sciences

  5. Gemin X Pharmaceuticals: Finding A Drug's Mechanism Of Action

    Gemin X, a pharmaceutical company focused on the discovery and development of advanced oncology
    therapeutics, approached Metabolon to run a metabolism profile for one of their compounds—GMX1777.

  6. Kinetic Analysis Of Antibodies From Different Cultured Media

    The Octet QKe platform is evaluated to establish an analytical method for assessing the effects of media condition on the quality and activity of cultured antibodies. By David Ho, Tom Fletcher, and Jessie H.T. Ni

  7. A High-Throughput Static Culture Flask Alternative To Shake Flask Culture

    Irvine Scientific specializes in developing and manufacturing cell culture media for bioproduction. To ensure the utility of the medium, CHO cell lines are tested for density, viability and productivity. By Brandy Nunez, Brian Canna, MBA, and Jessie Ni, PhD

  8. Analysis Of Dialyzed Flask Technology For Antibody Production

    Efficient and cost effective hybridoma culture is essential to small and large scale monoclonal antibody production for research purposes. By Denis Phichith, PhD and Brian Canna, MBA

  9. Connection Technology Advances Closed System Processing

    The global demand for new biologics and vaccines, combined with the growing emergence of biosimiliars, is challenging drugmakers to re-evaluate their processes and seek ways to make them more flexible, reliable, and cost-effective. By John Boehm, Colder Products Company

  10. Staying Current In Cold Chain Management

    Our aim with this article is to explore the latest revision of Chapter <1079> from the U.S. Pharmacopeial Convention (USP) and to address questions that Vaisala, as a creator of systems used in cold chain applications, receives from customers and contacts who manage temperature-controlled supply chains. By Paul Daniel and Piritta Maunu, Vaisala, Inc.