Novel Cell Lysis Solution: Scaling Up The Harvest Process While Preserving What Matters

By Beth Kroeger-Fahnestock Director, New Product Introduction (BioPharma), Avantor, Inc.

The ecotoxicity of Triton X-100 has clearly demonstrated that biomanufacturers should consider a change in their approach to cell lysis. To ensure patient safety — as well as a portable process outside of Europe — it’s time to find a novel reagent without harmful, endocrine-disrupting properties. This white paper presents study data on key features of 100X concentrated, ready-to-use J.T. Baker^® Cell Lysis Solution as a scalable alternative that provides complete cell lysis for viral vector recovery.