Newsletter | February 4, 2026

02.04.26 -- TFF Offers Ideal Anaerobic, GMP Conditions For LBP Concentration

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Webinar: Four Common Pitfalls to Avoid in UF/DF Setup and Scale-Up

UF/DF scale-up shouldn’t be where good processes fall apart. In this Repligen webinar, uncover four costly UF/DF pitfalls that derail programs—from membrane selection missteps to manual-heavy systems and PD–MSAT disconnects. Learn how early decisions impact scalability, timelines, and risk, and walk away with actionable strategies to build robust UF/DF processes that transfer smoothly to manufacturing. Click here to learn more.

FOCUS ON FILL-FINISH

5 Advantages Of Dual-Sourcing In Pharmaceutical Fill/Finish

Delve into the specific advantages of dual-sourcing in pharmaceutical fill/finish, exploring how this approach can bolster supply chain resilience, increase capacity, and accelerate commercialization.

Finding The Right Aseptic Processing Approach

How should you approach building your aseptic processing line? Gain insight into the advantages of using a modular, configurable technology rather than custom fill-finish solutions.

FILL-FINISH SOLUTIONS

Automate Your Fill/Finish Process For Precision - Terumo BCT

Leveraging Advanced Technology And Proven Expertise - Catalent

FOCUS ON DOWNSTREAM MANUFACTURING

TFF Offers Ideal Anaerobic, GMP Conditions For LBP Concentration

When configured correctly, TFF provides the gentle processing environment and oxygen protection required for strict anaerobes.

Optimize mAb Purification Using Protein A Membrane Chromatography

Uncover how high throughput (HTP) screening can utilize membrane chromatography at comparable consumables costs to traditional resins without compromising CQAs for prescribed therapeutics.

Viral Vector Sterile Filtration: Process Efficiency And GMP Alignment

Explore filtration strategies that improve viral vector yield and quality, with insights on AAV and lentivirus workflows, plus practical guidance for implementing PUPSIT in line with requirements.

Periodic Counter Current Chromatography: A Step Toward Continuous DSP

PCC boosts Protein A capture efficiency, cuts resin costs, increases productivity, and enables continuous downstream processing without sacrificing quality or compliance.

Automated PUPSIT For Drug Product Applications

Automated filtration systems streamline PUPSIT, leak testing, and integrity checks to ensure sterile drug product processing. See how these methods improve contamination control and compliance.

Top Five Downstream Processing Challenges For Viral Vectors And Exosomes

From discovery to patient doses, viral vectors and exosomes face a complex journey. Researchers must navigate five key downstream processing challenges to ensure these therapies reach their full potential.

Development Of Scalable Purification For Biotherapeutic Peptides

Discover key strategies for reversed-phase isolation of biotherapeutic peptides, as well as learn about method development, scale-up techniques, and RP/MS analysis to enhance purification workflows.

DOWNSTREAM MANUFACTURING SOLUTIONS

A Better Way For Closed-System Processing In Cell Therapy - CPC

Oligonucleotide Manufacturing: End-To-End Solutions - Entegris, Inc.

Particle Loss Studies - Particle Measuring Systems

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