Article | February 25, 2025

Countdown To Zero: Overcoming Downstream Processing's Top Five Challenges For Viral Vectors And Exosomes

Source: RoosterBio
GettyImages-1076055404 chromatography, purification
Credit: Getty Images

Viral vectors and exosomes, while revolutionary in their potential, present significant hurdles in downstream processing – the critical steps after production that purify and refine these delicate biological entities. Imagine trying to isolate a specific grain of sand from a beach, and you begin to grasp the complexity. From scalability bottlenecks to maintaining product integrity, the journey from bioreactor to patient is fraught with challenges. These downstream obstacles can be the difference between a groundbreaking therapy reaching patients and remaining confined to the lab.

This article examines the critical roadblocks hindering the efficient production of viral vectors and exosomes, and more importantly, how to overcome them. Read the full article to discover the top five downstream processing challenges and gain actionable insights to accelerate your path to clinical success.

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