Given the complexity of mRNA, rigorous characterization and testing are required to ensure safe and effective mRNA drug products. This white paper provides a detailed description of assays for sequence identification and LNP composition, two critical quality attributes of mRNA-LNP products. Learn more.
Orca Bio's Dan Kirby has played a hand in prepping more than a few approved biologic therapeutic candidates for commercialization. Equally important, he knows firsthand what makes or breaks post-approval commercial efforts, having played virtually every role there is to play in drug sales and marketing.
Current processes in recombinant adeno-associated virus-based gene therapy production are generally not readily scalable. A group of scientists and engineers at MIT collaborated with the team at UMass Chan Medical School to develop a mechanistic model for the intracellular phenomena occurring during baculovirus infection and rAAV virion production in insect cells. A free and user-friendly implementation of the model is available online, and anyone can use it to test a wide range of conditions and hypotheses.
Addressing Cell Line Development Bottlenecks
Explore study results demonstrating the ability of a specialized reagent to substantially improve the cell line development workflow cloning phase for the manufacture of protein biologics and viral vectors.
LNP Formulation For mRNA Delivery
Microfluidic mixing is one of the most effective means to formulate lipid nanoparticles (LNPs). Explore LNP formulation, polishing, sterile filtration of mRNA-LNPs, and more.
The Cell & Gene Meeting on the Mesa is the sector’s foremost annual conference bringing together senior executives and top decision makers in the industry to advance cutting-edge research into cures. This year’s program will feature expert-led panels, extensive partnering capabilities, exclusive networking opportunities, and 100+ dedicated presentations by the leading publicly traded and privately held companies in the space. Register today.
LIFE SCIENCE LEADER MAGAZINE
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