INSIGHTS ON DOWNSTREAM MANUFACTURING

• Optimize Time, Space and Cost With Inline Buffer Formulation And System

  Discover how integrating inline buffer formulation with chromatography reduces buffer waste by 50% and delivers a 710% ROI, transforming downstream efficiency and sustainability.

• Evaluation Of TFF Operating Control Strategies And Scalability

  Gain insight into a comparison of TMP and permeate control strategies for viral vector TFF, highlighting impacts on flux, processing time, impurity removal, and scale-up predictability across development.

• The Effect Of Conventional Cooling Versus Controlled Ice Nucleation On Primary Drying Time

  See how controlled ice nucleation shortens lyophilization cycles, supports higher drying temperatures, and reduces complexity for amorphous and mixed formulations without sacrificing quality.

• Performing Virus Clearance Studies With Retroviral-Like Particles: Updated Guidance

  Updated regulatory standards now support using non-infectious retroviral-like particles for viral clearance. This shift reduces costs and accelerates timelines for biomanufacturers.

• A Gentler Workflow: Fc-fusion Protein Purification With Mixed-Mode And Anion Exchange Chromatography

  3/26/2026

  Gain insights into comparative performance, workflow flexibility, and practical considerations for implementing a new weak anion exchange hydrophobic resin and a strong anion exchange resin.

• WuXiHigh 2.0 Delivers A 180 mg/mL Formula

  3/26/2026

  This case study shows how smart formulation and integrated development achieved a stable 180 mg/mL biologic for subcutaneous delivery, for teams tackling concentration issues.

• Tool Enzymes For Antibody-Drug Conjugate Development And Manufacturing

  3/26/2026

  See how modern tool enzymes enable cleaner, more consistent ADC conjugation, sharper analytics, and a smoother path from research to clinical development — practical guidance for manufacturing.

• Ensure Successful Viral Clearance

  3/26/2026

  A decade of viral clearance data comparing established and emerging operations, highlighting LRV performance, key process risks, and practical insights to strengthen downstream safety.

• AST Origins: Pioneering RTU Flexibility With Robotic Fill-Finish Systems

  3/25/2026

  Modernize sterile manufacturing with robotic fill-finish systems. Achieve multi-format flexibility and risk reduction to meet the rigorous demands of personalized medicine and small-batch production.