INSIGHTS ON DOWNSTREAM MANUFACTURING
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Accelerating Early Phase Biologics From The Clinic To Commercialization
Strategic planning in early-phase biologics accelerates clinical progress, reduces risk, and lays the groundwork for scalable, compliant manufacturing and successful commercialization.
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Cell Culture Media Mixing In A Benchtop Single-Use Mixer
Explore how efficient powder-liquid mixing and sterile filtration preserve media integrity and support reproducibility in biopharmaceutical workflows, with promising scalability for larger-volume applications.
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Biopharma Supply, Reimagined: Blarney, A Climate-Neutral Facility For Best-In-Class Filters
Explore how a new, climate-neutral manufacturing facility strengthens biopharma supply chains. Understand the benefits of its advanced filtration technologies and commitment to environmental sustainability.
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High Capacity, Scalable Cation Exchange Chromatography Membrane For Purification Of Monoclonal Antibody
Overcome binding capacity limitations in mAb purification. A new hydrogel membrane enhances productivity 30x over resins, offering superior loading capacity and consistent, scalable impurity removal.
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Sterile Filtration: Filter Sizing For Process Optimization11/11/2025
Correctly sizing sterilizing-grade filters is crucial for optimizing sterile filtration processes. Learn how Pmax and Vmax methodologies impact efficiency, cost, and filter performance, including the role of pre-filters.
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Ecolab, Purolite Resins Bio-Expo Live November 2025: Downstream Bioprocessing11/11/2025
Explore how a modular affinity resin toolbox can address purification challenges, delivering high dynamic binding capacity, minimal aggregation, and caustic durability for antibody capture.
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Transforming Nanoparticle Formulations From Bench To Commercial Scale11/11/2025
Unlock seamless transition from lab-scale nanoparticle research to commercial production. Learn how scalable turbulent-jet mixing ensures precise, uniform, and reproducible formulation results.
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Scale Up: Supporting Easy Scalability All The Way To Manufacturing11/11/2025
Achieve seamless purification scale-up from development to manufacturing using integrated chromatography and TFF systems. Optimize workflows, ensure batch consistency, and accelerate time to market.
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Intensified Antibody Purification With Membrane Chromatography11/10/2025
Learn how membrane chromatography can help overcome downstream bottlenecks in mAb purification, reduce costs, and support process intensification from development to GMP scale.
DOWNSTREAM MANUFACTURING SOLUTIONS
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Gene therapies hold immense potential to provide long-lasting treatments for a wide range of diseases. At Cytiva, we offer GMP-compliant, end-to-end manufacturing solutions designed to support the development and commercialization of advanced medicines across multiple modalities – including AAV, adenovirus (AV), lentivirus (LV), plasmid DNA (pDNA) and exosomes. Our dependable suite of technologies and expertise ensures scalability, quality, and regulatory confidence at every stage of your journey.
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Platform of automated, single-use systems for tangential flow filtration at multiple scales.
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ÄKTA ready™ 450 system is a single-use liquid chromatography system.
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Downstream process intensification offers major gains, but only with the right strategy. Learn how chromatography selection and expert input can help align purification workflows with production goals.
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Automated, parallel tools simplify protein purification to streamline screening, prep, and analytics with scalable formats and intuitive software for reproducible chromatography and MS workflows.