Adenoviruses are commonly used as gene transfer vectors in gene therapy and clinical trials. However, their large size, complexity, and acid labile nature lead to challenges in their downstream purification.

A helpful set of criteria to help you compare and evaluate the features of the best-in-class integrity test instruments and to make informed choices.

How the adoption of innovative technologies to perform timely measurements on critical quality attributes (CQAs) of raw and in-process materials allows better process understanding and control.

By recognizing the limitations of today’s production processes, the industry may be able to overcome the challenges, complexity, and high cost of manufacturing vaccines and viral vector-based therapies.

Reference methods for packing columns with Nuvia IMAC Resin : From Lab-Scale to Process Scale. This collateral details the packing of Nuvia IMAC in 3 different column sizes.

In this video Bio-Rad's Process Chromatography Consultant, Jim Sulzberger speaks about continuous bioprocessing and chromatography resins.

This video reviews a DoE Workshop that provided best practices and guidelines for DOE experiments using mixed-mode chromatography resins.

A focus on strategies for virus and monoclonal antibody purification, viral clearance, and aggregate removal challenges

This video features a presentation of the analysis of the over all performance of different chromatography types based on their internal database looking specifically for the log reduction factors for the most testable viruses; MuLV, MVM, PRV, and Reo-3.