INSIGHTS ON DOWNSTREAM MANUFACTURING

• LVV Manufacturing: Old But Gold Gene Therapy Viruses?

  Discover how plasmid design, transfection protocols, and controlled freezing methods combine to address critical manufacturing challenges in lentiviral vector production for gene therapy applications.

• Quality Assurance In Pharmaceutical Water For Injection (WFI) Systems

  Maintaining the integrity of Water for Injection (WFI) systems is a non-negotiable priority in pharmaceutical manufacturing. Watch this webinar to refine your contamination control strategies.

• Method Development For Forced Degradation Of GLP-1 Agonist

  Gain insight into how a systematic approach reveals impurity behavior, strengthens selectivity, and refines chromatographic conditions to build a reliable degradation method for a GLP‑1 agonist.

• Denaturing SEC-MS Analysis Of High Molecular Weight Impurities

  Look at how denaturing SEC‑MS uncovers low‑level oligomers and truncated variants in GLP‑1 peptides, offering clarity on impurity profiles and supporting confident assessment of molecular integrity.

• Digital Twin For Fill-Finish: Overview And Use Cases

  3/16/2026

  Digital twin technology optimizes aseptic fill-finish through real-time mirroring and predictive simulation. Improve yields and validate complex recipes by integrating dynamic virtual models.

• De-Risking A Novel Valve Component For Use With Standard Syringe Systems

  3/16/2026

  A novel valve provides dual‑chamber functionality within standard syringes, keeping two liquid drugs separated until injection while reducing development risk through advanced modeling.

• LNP And Liposomal Center Of Excellence

  3/10/2026

  A connected development pathway supports smoother scale-up and greater consistency for LNP-based therapeutics. Explore how integrated expertise across key stages helps teams accelerate progress.

• The Importance Of Process Locks To Align Upstream And Downstream

  3/9/2026

  In this closing segment from the Bioprocess Online Live event “Optimizing Process Development Through Upstream And Downstream Integration,” the panelists emphasize the importance of periodic process locks to ensure alignment between upstream and downstream development teams. These locks are critical, says Eric Doerr, a manufacturing lead at Sanofi, because they allow both upstream and downstream to have a better understanding of the process and keep them on the same page.

• Feed Media Can Significantly Impact Process Performance

  3/9/2026

  In this segment from the Bioprocess Online Live event “Optimizing Process Development Through Upstream And Downstream Integration,” our panelists respond to an audience question about feed media and its impact on process performance.