INSIGHTS ON DOWNSTREAM MANUFACTURING

  • Single-pass Tangential Flow Filtration For Bioprocessing

    Experiencing bottlenecks in your downstream process? Pellicon® Single-Pass TFF increases your productivity, capacity while reducing costs!

  • Concentrate Your Product After One Path With Pellicon® Single Pass Tangential Flow Filtration

    Discover Pellicon® Single-Pass Tangential Flow Filtration, the versatile ultrafiltration technology for process intensification.

  • Designing Quality Into Chromatography Resins To Minimize Variability

    Chromatography resins and adsorptive membranes occupy a central role in the downstream purification of biologics and as such, the raw materials and processes used to manufacture these materials directly impact their performance. Assurance of quality and lot-to-lot consistency begins at the earliest stages of the research and process development phases, when new resins and membranes are being conceptualized and designed to meet the evolving needs of our customers. This article explores the strategies and close collaboration employed by MilliporeSigma to design quality into resins and membranes and to help customers minimize variability in their purification process.

  • Planova BioEX

    Planova BioEX provides assurance beyond expectation with superior filtration performance, combined with its robust virus removability and excellent scalability.

  • LC Systems And DAC LC Columns

    Let Asahi Kasei Bioprocess modernize your next recombinant protein or oligonucleotide manufacturing plant with the ergonomic DAC LC Columns and flexible LC Systems that are built for you.

  • Inline Buffer Dilution And Formulation

    Discover our award-winning IBD™ technology and see how it generates accurate and reproducible buffers on-demand from concentrates to save you time, space and money.

  • DAC ERGO

    Explore how to conduct safe, efficient maintenance on large-scale stainless steel DAC Liquid Chromatography Columns with the DAC Ergo package, which allows a single operator to remove the bottom plate assembly in under fifteen minutes.

  • Designing Chromatography Resins To Ensure Process And Supply Transparency

    Chromatography resins are often sourced from a single supplier as the qualification process is lengthy and costly. As a result, security of supply is of high importance to our customers and to us. To improve on-time delivery reliability, and product quality of our chromatography resins, we have implemented a robust process. Watch the video to learn more.

  • Hyper-Productivity In Your mAb Purification Step

    Learn how a tenfold increase in productivity of 200 g/L/h compared to the industry norm was possible through an intensified Protein A capture process.

DOWNSTREAM MANUFACTURING SOLUTIONS

  • Flexible Manufacturing Of Vaccines

    Flexible manufacturing accelerates vaccine development and production to ensure that vaccines are available where and when they are needed most. We can guide you through each step of your complex journey to establish a single-use facility.

  • Thermo Scientific Labtainer Pro BioProcess Container (BPC)

    As technology and innovation advance within the bioprocessing industry, single-use technologies have also made considerable progress in the drug and vaccine manufacturing space. The innovative concept of the Thermo Scientific™Labtainer™ Pro BioProcess Container (BPC) provides flexibility and assurance—without compromise.

  • Inline Buffer Formulation

    Our award-winning IBD™ technology, generates accurate and reproducible buffers on-demand from concentrates to save you time, space and money.

  • Asahi Gold Particle Test System-II

    Fast and reliable post-use integrity testing for Planova™ 15N, 20N and 35N filters.

  • Viral Clearance Study Support

    The Field Applications (FA) team is focused on providing support to Planova™ filter users, including optimizing and conducting viral clearance study (VCS) filtrations at your selected BSL-2 laboratory. While holding your study parameters and data in the strictest confidence, we work to optimize your VCS plan to ensure the best possible outcome.