INSIGHTS ON DOWNSTREAM MANUFACTURING

• Controlled Nucleation Offers Homogeneity And Batch Consistency

  Controlled nucleation standardizes freezing across all vials, leading to uniform ice crystals and improved lyo cake quality. This critical step reduces variability and supports robust product scale-up.

• mAb Purification: A Two-Step Approach Using A Strong AEX-HIC Mixed-Mode Resin

  Elevate your mAb purification with a two-step chromatography strategy. Simplify the process, eliminate an entire step, and achieve substantial savings in time and material costs.

• Rapid Process Development For Cell Line Optimization Using Protein A

  Rapidly purify 24 monoclonal antibody samples in under eight hours with a membrane-based affinity capture that streamlines cell line optimization and accelerates early-stage bioprocess development.

• End-To-End Solutions For Biopharma Bottles

  Until recently, only isolated solutions for working filling, freezing/thawing and transporting sensitive drug materials were available. Learn how we've addressed this problem with end-to-end bottle solutions.

• Virus Retention Performance Under Diverse Processing Conditions

  11/14/2025

  Virus filtration is robust across a wide range of process parameters, including high protein concentration and flow decay. Discover how retention relies on size exclusion to simplify risk assessment.

• Accelerating Early Phase Biologics From The Clinic To Commercialization

  11/13/2025

  Strategic planning in early-phase biologics accelerates clinical progress, reduces risk, and lays the groundwork for scalable, compliant manufacturing and successful commercialization.

• Cell Culture Media Mixing In A Benchtop Single-Use Mixer

  11/13/2025

  Explore how efficient powder-liquid mixing and sterile filtration preserve media integrity and support reproducibility in biopharmaceutical workflows, with promising scalability for larger-volume applications.

• Quality Control In IVT RNA Workflow

  11/12/2025

  Accurate sizing and purity checks are essential in IVT RNA workflows. Explore how automated electrophoresis improves QC efficiency and ensures RNA integrity for downstream applications.

• Biopharma Supply, Reimagined: Blarney, A Climate-Neutral Facility For Best-In-Class Filters

  11/11/2025

  Explore how a new, climate-neutral manufacturing facility strengthens biopharma supply chains. Understand the benefits of its advanced filtration technologies and commitment to environmental sustainability.