INSIGHTS ON DOWNSTREAM MANUFACTURING
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![GettyImages-1363784042 chromatography, samples, resin]( "Periodic Counter Current Chromatography: A Step Toward Continuous DSP")
Periodic Counter Current Chromatography: A Step Toward Continuous DSPPCC boosts Protein A capture efficiency, cuts resin costs, increases productivity, and enables continuous downstream processing without sacrificing quality or compliance.
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![Scientist in HPLC lab GettyImages-1309780330]( "Twist Of Two: 2D-LC For Oligos")
Twist Of Two: 2D-LC For OligosDiscover how coupling orthogonal mechanisms reveals hidden impurities and creates a more robust strategy for characterizing complex oligonucleotide samples.
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![KNAUER - sepapure_oligo]( "A New Specialist For Oligonucleotides With Advantages")
A New Specialist For Oligonucleotides With AdvantagesDiscover how hybrid silica technologies ensure stability and high resolution in IP-RP chromatography applications while protecting instrumentation from excessive wear and tear.
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![GettyImages-1076055404 chromatography, purification]( "The Secret To Pure Oligos: Why Anion Exchange Chromatography Rules At Scale")
The Secret To Pure Oligos: Why Anion Exchange Chromatography Rules At ScaleDiscover how anion exchange chromatography delivers high loading capacity and clinical-grade purity while addressing common scale-up challenges like aggregation and equipment longevity.
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How To Navigate Through The Jungle Of Columns?12/15/2025
Whether prioritizing mass spectrometry compatibility or loading capacity, understanding the specific trade-offs between IP-RP, AEX, and SEC methodologies is essential for successful characterization.
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Size Matters: Mastering Size Exclusion For Oligos12/15/2025
Learn how to separate molecules strictly by size, effectively remove salts, and select the correct pore specifications for a gentle, non-destructive purification workflow.
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Charged For Action: The Hidden Secrets Of AEX Oligonucleotide Analysis12/15/2025
Understanding how to fine-tune pH and ionic strength allows for the detection of truncated sequences and single-nucleotide variants, turning complex purification challenges into reproducible data.
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The Hitchhiker´s Guide To Creating Oligonucleotides From Start To Finish12/15/2025
Producing high-quality oligonucleotides demands precise execution across multiple stages. Gain a clearer understanding of the complete mid-scale production workflow and necessary quality control measures.
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How To Reduce Batch Loss In Biopharma Production12/12/2025
Batch failures in biopharma remain costly despite improvements. Learn the leading causes in downstream purification and how supplier expertise can help reduce risk and protect production.
DOWNSTREAM MANUFACTURING SOLUTIONS
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![Asahi Kasei - Sluriprep]( "Slurry Handling Solutions")
Streamline your media preparation and column packing. Achieve greater consistency and safety with advanced slurry handling solutions designed for high productivity.
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![Asahi Kasei - SCS]( "Synthesis Columns: THESYS® SCS Column And THESYS® ACS Column")
Explore how advanced synthesis columns with specialized flow distribution and ergonomic design optimize reagent dispersal and simplify maintenance to support rigorous cGMP manufacturing requirements.
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![asahi kasei - VANTIJ_SU-VFC]( "VANTIJ® Virus Filtration Solutions")
Learn about automated systems that bridge the gap between filtration and buffer recovery, enhancing reproducibility and efficiency across clinical and commercial manufacturing scales.
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![Asahi Kasei - VANTIJ]( "VANTIJ® Single-Use Virus Filtration Controller")
Automating critical filtration steps significantly reduces cross-contamination risks and operational costs. This single-use approach ensures process repeatability and eliminates cleaning downtime.
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![GettyImages-1351826681-capping-vials-fill-finish]( "Aseptic Manufacturing: Fill/Finish For Vials, Syringes, Cartridges")
Sterile fill/finish requires isolator technology and regulatory compliance. From clinical development to commercial scale, technical expertise ensures the integrity of liquid and lyophilized injectables.
