Upstream Manufacturing

INSIGHTS ON UPSTREAM MANUFACTURING

Catalent Capabilities Update June 2026: Cell Line Development
Discover how an integrated approach to transient expression, cell line development, and manufacturing can accelerate biologics development from gene to IND.
LNP-Mediated Cell Transfection In Bioreactors Across Workflows
Lipid nanoparticles are redefining immune cell engineering. Delve into new data that demonstrates the performance across multiple cell types and bioreactor systems, supporting their potential workflows.
Enhancing Host Cell DNA Testing With Digital PCR
Residual host cell DNA testing is evolving with digital PCR. Discover how streamlined methods improve accuracy, minimize manual steps, and support efficient biopharmaceutical manufacturing processes.
A Clear Path To Rapid, Consistent Biosimilar Development
Faster timelines don’t have to come at the expense of quality or consistency. Discover proven strategies to generate stable, high-performing cell lines while reducing risk and supporting reliable scale-up.

Filtration In Preparation Of Cell Culture Media And Buffers
6/22/2026

Refine media and buffer prep with filtration that removes particles, reduces bioburden, and safeguards sterility — protecting processes, preventing contamination, and consistent biopharma performance.
How Intensified Upstream Processing Improves Scale-Up And Tech Transfer
6/22/2026

Intensified upstream processing can improve scalability and maintain quality. Learn how automation, PAT, and data-driven control strategies help modernize workflows and support consistent performance.
From Process Monitoring To Manufacturing Intelligence: Real-Time Analytics And Predictive Control In Biomanufacturing
6/19/2026

Advanced analytics, predictive modeling, explainable AI, and digital twins are helping biomanufacturers improve process visibility, anticipate outcomes, and support smarter operational decisions.
Towards A Universal LNP Platform For Multiplex Engineering
6/19/2026

Multiplex engineering of T cells for solid tumors requires precise delivery. Emerging LNP approaches enable co-delivery of RNA and DNA, offering a safer, more scalable path beyond viral vectors.

From Cell Line To Clinic: 4 Months Sooner With mAb Accelerator

Launch cell line development during funding to save four months, beating early bottlenecks and reducing capital risk with milestone-aligned models.
Bring Greater Control To Your Cell Therapy Manufacturing

Learn how automating activation, transduction, and expansion in a closed workflow can simplify operations, reduce manual steps, and improve consistency while enabling real-time monitoring.
Upstream Bioprocess Equipment For Commercial Manufacturing

Transform your bioprocessing workflow with intelligent, user-friendly systems that combine precision engineering with operational excellence for superior outcomes.
Single-Use Bioreactors For Cell Culture, Fermentation, And Commercial Manufacturing

Enhance your bioprocessing with single-use bioreactors that offer broad compatibility, reduced turnaround times, and consistent product yield through innovative design and flexible scalability.
Early Stage Capability From Sequence To IND And Beyond

See early-stage CDMO capabilities at a specialized bio campus, detailing process development, analytical support, bioconjugation services, cell banking, and scalable manufacturing solutions.