By applying remote monitoring solutions, advanced modeling, and optimization of manufacturing processes, Industry 4.0 offers improved process reliability and product quality through unlimited possibilities of connecting machines and data.
Using its Supplier Relationship Excellence (SRE) program, Amgen opened the lines of communication with suppliers and created a feedback loop where data can be shared to better understand operational performance.
To drive appropriate and dependable critical process control requirements, Biogen explored several novel strategies to increase process and raw material control and optimize communication of data throughout the supply chain.
Gain an understanding of exosomes which are recently attracting attentions of researchers as new mediators of cell-cell communication transporting biomolecules such as lipids, proteins, and RNAs in vivo.
Recent innovations in Single-Use technologies (SUT) have allowed traditional microbial fermentation processes to quickly capture the established benefits that have been proven over the past decade with animal cell culture processes when using disposable processing equipment.
This study presents how strategic enhancements to the sparge and agitation systems of Thermo Scientific HyPerforma S.U.B.s have revealed the potential for a three- to four-fold improvement in mixing and mass transfer performance compared to legacy S.U.B. designs.
Watch this video to learn more about this manufacturing site capabilities, quality management systems, PPI implementation, product expansion, assurance of supply and lead times.
The Viresolve® Barrier filter offers opportunities for efficient processing of cell culture media components to reduce the risk of bioreactor contamination.
See how GE Healthcare products that are currently used in the cell processing workflow for cell therapy.
In this webinar, you will learn about demonstrating the process development and scale-up of a recombinant CHOZN® GS clone in EX-CELL® Advanced™ cell culture media from small-scale up to 50 L pilot scale.
In taking a more strategic view toward monoclonal antibody manufacturing, there is a drive to develop processes with higher productivity and improved economics without sacrificing robustness or quality.
A webinar to learn about challenges faced with traditional expression systems and how a CHO cell line with the glutamine synthetase knock-out via ZFN provides benefits for fast, efficient cell line development with stable and high titer expression.
Choose the right process development and manufacturing partner to guide your company through the many parameters along the drug development process.
Flexible, reliable control and bioreactor systems for laboratory applications
Thermo Scientific™ HyPerforma™ bioprocess control systems are designed to optimize your process from the laboratory bench to full cGMP manufacturing. Our innovative control platform combines a flexible operating system with scalable, modular hardware, novel single-use sensors, and state-of-the-art bioreactors for strategic and streamlined bioprocess control.
HyPerforma benchtop solutions offer robust management of both cell culture and fermentation processes. The open architecture provides process flexibility, and dedicated hardware control allows for expansion. Thermo Scientific™ TruBio™ software is designed to support easy process control and scaling.
Flexible, reliable control and bioreactor systems for laboratory applications.