INSIGHTS ON UPSTREAM MANUFACTURING
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When Your Expression System Isn't Cooperating With Your Protein
When a protein resists an established expression system, the issue may be host-platform mismatch rather than a fundamentally difficult molecule.
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A Comprehensive Solution With Targeted And Non-Targeted Approaches
Explore how non-targeted NGS and targeted molecular assays can work together during cell line characterization to provide broad virus detection while supporting evolving regulatory expectations.
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Driving Measurable Productivity Gains In CHO Cell Culture
Explore how targeted media supplementation can improve CHO cell culture outcomes, simplify process optimization, and increase productivity across monoclonal antibodies and emerging modalities.
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Fusion-Enabled Biosimilar Peptide Teriparatide Expression
See how high-throughput fusion partner screening identified teriparatide production strains exceeding 6 g/L expression, supporting biosimilar comparability assessment and commercial manufacturing readiness.
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Cryopreserved Autologous Cell Therapy Workflow Processing8/21/2026
A closed, automated centrifuge system achieves consistent cell recovery and viability across leukopak donors and wash media, addressing key limitations of manual cell therapy processing.
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Optimizing Liquid And Solid Mixing Across Variable Process Volumes8/20/2026
Discover how working volume, material type, and solids behavior affect single-use mixing performance, with practical findings on blend times, homogeneity, analytical methods, and agitation rates.
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Evaluating Mixing Performance Across Liquids, Solids, And Powders8/20/2026
Analytical readings may indicate uniformity before mixing appears visually complete. Explore how material behavior, agitation, working volume, and addition methods affect mixing times.
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Reliable Mixing Across Changing Batch Volumes8/20/2026
See how working volume and agitation speed influence mixing, with practical performance data to help teams assess efficiency across a broad range of upstream and downstream operating conditions.
UPSTREAM MANUFACTURING SOLUTIONS
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When E. coli, CHO, and yeast fall short on titer, protein quality, or scalability, a P. fluorescens-based expression platform built on 25 years of strain engineering offers a different path.
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Learn about a single-use tubular bowl centrifuge platform that delivers high cell viability and recovery across multiple cell therapy manufacturing steps, from gene editing through final formulation.
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Unused 500-liter Cytiva bioreactor system, model XDR-500. Includes workstation controller, serial# 29708722.
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Used 200 liter Sartorius single-use jacketed bioreactor, model BIOSTAT CultiBag STR 200-DW. Includes Watson Marlow model 323 digital peristaltic pump, load cells with Sartorius model Midrics 1 display terminal, serial# STR 0583, built 2016, with Sartorius Stedim stirred single-use bioreactor touchscreen controller, model BIOSTAT CultiBag STR Plus. Includes (4) peristaltic heads, serial# 00716/16.
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Unused 50 liter Sartorius Biostat RM 50 (rocking motion) single-use bioreactor, built 2022.