INSIGHTS ON UPSTREAM MANUFACTURING

  • 2,000 L HyPerforma Single-Use Bioreactor Evaluation
    2,000 L HyPerforma Single-Use Bioreactor Evaluation

    The stirred-tank reactor is the most commonly utilized reactor type in biotechnology. Read more about the Thermo Scientific™ HyPerforma™ Single-Use Bioreactor (S.U.B.). It is designed as a stirred-tank reactor for animal cell culture and has the unique advantage of utilizing completely single-use product contact surfaces.

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UPSTREAM MANUFACTURING MULTIMEDIA

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UPSTREAM MANUFACTURING SOLUTIONS

  • HyPerforma Glass Bioreactors
    HyPerforma Glass Bioreactors

    The Thermo Scientific™ HyPerforma™ Glass Bioreactors are available in 1, 3, 7, and 15 L sizes. They offer easy operation and rapid assembly and are manufactured with the highest standards for materials and surface finish. Developed using a computational fluid dynamics (CFD) simulator, the HyPerforma Glass Bioreactor impellers provide maximum mixing with minimum shear force, resulting in a higher average kLa. The cold finger has been replaced by a cooling loop to increase the thermal surface. Laboratory performance tests have demonstrated a cooling rate two times better than a sample of products from other suppliers. Control can be bidirectional, which allows a single-wall vessel to be used for mammalian applications and fermentation processes* (needs two kits).

  • Flexible, Reliable, And Configurable Bioprocessing Solution

    Read more about solutions offered from Thermo Scientific including the HyPerforma™ G3Lite™ Controller, TruBio upstream software, HyPerforma S.U.B., TruFlow gas mass flow controller (MFC) and other products for your process development and production operations.

  • Production Scale Bioprocessing Solutions
    Production Scale Bioprocessing Solutions

    Flexible, reliable, and configurable bioprocessing solutions
    The Thermo Scientific™ HyPerforma™ G3Lite™ Controller is an open architecture control system that can be integrated with any single-use bioreactor such as the Thermo Scientific™ HyPerforma™ Single-Use Bioreactor (S.U.B.) (Available in sizes ranging from 50 L to 2,000 L). The system consists of a control tower that leverages intelligent transmitters, mass flow controllers (MFCs), pumps, sensors, and Thermo Scientific™ TruBio™ software that facilitates easy, reliable, and repeatable process development and commercial cell culture processes. HyPerforma G3Lite Controllers are fully self-contained, movable units that can be operated as stand-alone (for 1 vessel) or networked for multiple vessels. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.

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