Upstream Manufacturing

INSIGHTS ON UPSTREAM MANUFACTURING

LNP-Mediated Cell Transfection In Bioreactors Across Workflows
Lipid nanoparticles are redefining immune cell engineering. Delve into new data that demonstrates the performance across multiple cell types and bioreactor systems, supporting their potential workflows.
How Intensified Upstream Processing Improves Scale-Up And Tech Transfer
Intensified upstream processing can improve scalability and maintain quality. Learn how automation, PAT, and data-driven control strategies help modernize workflows and support consistent performance.
From Process Monitoring To Manufacturing Intelligence: Real-Time Analytics And Predictive Control In Biomanufacturing
Advanced analytics, predictive modeling, explainable AI, and digital twins are helping biomanufacturers improve process visibility, anticipate outcomes, and support smarter operational decisions.
Towards A Universal LNP Platform For Multiplex Engineering
Multiplex engineering of T cells for solid tumors requires precise delivery. Emerging LNP approaches enable co-delivery of RNA and DNA, offering a safer, more scalable path beyond viral vectors.

Extrahepatic Delivery Of mRNA-LNP To Spleen
6/19/2026

In vivo CAR-T approaches aim to reprogram T cells directly in the body using targeted lipid nanoparticles. Improved delivery to immune organs highlights new potential for scalable cell therapies.
Generate Stable High-Producing Clones In 14 Weeks
6/18/2026

Rising complexity is putting pressure on cell line development. Discover a streamlined approach that enables rapid generation of stable clones with strong titers and long-term consistency.
Where Speed Meets Complexity In Bioprocess Development
6/18/2026

Bioprocessing faces mounting pressure to compress timelines, especially for mAbs, while complex modalities like bispecifics and gene therapies introduce technical challenges. Process intensification, scale-up translation, and comparability risks remain critical hurdles.
The Scale-Up Of A Transient rAAV8 Production Process
6/18/2026

New approaches to suspension cell culture and process scaling enable consistent, high-titer rAAV production. Gain insight into a clearer path to scalable manufacturing for gene therapy pipelines.

From Cell Line To Clinic: 4 Months Sooner With mAb Accelerator

Launch cell line development during funding to save four months, beating early bottlenecks and reducing capital risk with milestone-aligned models.
Early Stage Capability From Sequence To IND And Beyond

See early-stage CDMO capabilities at a specialized bio campus, detailing process development, analytical support, bioconjugation services, cell banking, and scalable manufacturing solutions.
Upstream Bioprocess Solutions From Research To Commercial Manufacturing

Bioprocessing is at the heart of many industries and Eppendorf has the right solutions for all of them.
Support Growth: A Solid Support Growth Material For Cell Culture

Higher cell density and improved process consistency start with the right growth environment. This structured cell attachment helps streamline scale-up with unique protection to maintain strong viability across demanding bioprocess applications.
Flexible From Head To Toe: One Bioprocess Controller For All Your Needs

Flexible bioprocess control enables seamless transitions from development to scale, combining automation, intuitive operation, and precise environmental management to improve efficiency, reproducibility, and adaptability.