Upstream Manufacturing

INSIGHTS ON UPSTREAM MANUFACTURING

Building A Resilient Supply Chain For Complex IVD Reagents (Or Proteins)
Explore how matching expression systems to diagnostic protein needs can improve yield, consistency, and scalability while reducing supply risks for IVD assays.
Cytovance Capabilities Update October 2026: Large Molecule
Move biologics from research and development toward commercialization with integrated development, analytics, scalable GMP manufacturing, and early-phase fill-finish capabilities.
Advances In ADC Development And Manufacturing
ADC manufacturability starts at molecule design, not downstream rescue. Learn how operator exposure to high-potency payloads shapes how conjugation workflows are built and qualified.
Streamlining Clonal Cell Line Selection With Susan Sharfstein, Ph.D.
In this episode of “Better Biopharma,” host Tyler Menichiello is joined by Susan Sharfstein, Ph.D., a professor of nanoscale science and engineering at the University at Albany’s College of Nanotechnology, Science, and Engineering.

The Importance Of Starting Material In Breakthrough Cancer Treatments
11/2/2026

Autologous TIL therapy starts with patient biology no developer can standardize. Discover which parts of the process can be controlled, and how far that goes toward reproducible products.
Breaking The DoE Bottleneck In Biologics Development
10/29/2026

Advanced screening designs reduce experimental burden while identifying critical process parameters, accelerating biomanufacturing optimization and process development.
Biologics Characterization Through Machine Learning
10/29/2026

Space-filling designs and ensemble machine learning can characterize a six-factor gene therapy process in just 24 runs, reducing time and materials.
Collaborating For Supply Chain Resilience
10/28/2026

Cell culture media supply resilience shapes continuity. A global CDMO's approach to tariff exposure spans both proprietary formulations and standard media, showing how supply strategy holds up.

Complex ADC Development. Simplified. One Coordinated European Platform

Successful targeted oncology programs combine biological engineering, potent compound synthesis, and efficient manufacturing to reduce complexity and speed clinical progress.
TheraPEAK® ActiCell® T Cell Activation Reagent

Bead-free activation of human T cells through biodegradable nanoparticles aims to protect cell health during expansion, with the reagent cleared by simple washing or centrifugation.
Quantum Flex Cell Expansion System: Inspired By Human Biology, Designed To Scale

Cell expansion built around low seeding requirements and high yields in 1 L or less. A bioreactor design drawn from human biology aims to simplify scale-up.
Guaranteed Tech Transfer And Process Development – Or Your Money Back

De-risk biotech development with guaranteed tech transfer and process support. Safeguard your investment from cell line development through protein optimization.
Nunc Cell Factory Systems: For Consistent Cell Culture Performance

Scaling adherent cell culture from flasks to multilayer systems depends on surface consistency, aseptic connections, and more. See how ultrasonic welding and retention hardware shape that path.