Oncolytic viruses constitute a new promising therapeutic approach for treatment of cancer. Here’s an example of a scalable, end-to-end process for oncolytic adenovirus production using modern tools and technologies.
With the uptake of single-use bags in cell culture processes, some manufacturers have reported inconsistent cell growth. Read how Sartorius has addressed the challenge of cell growth performance in single-use bags with their Flexboy® bags and new Flexsafe® platform.
Using rocking bioreactor systems can shorten the seed train prior to inoculation and provide optimized growth conditions for sensitive cells. This study presents a robust production of adenovirus using a rocking bioreactor system.
Increasing the integration of upstream and downstream processing and moving toward increased automation results in greater optimization of process efficiency - a key goal for biopharmaceutical production.
Bioprocessing has been used for decades for the industrial production of beverages and for the production and preservation of food and feed ingredients. The ability to monitor and control critical process parameters is a prerequisite. Read how researchers are tackling the challenges in food and feed applications, both old and new.
Stem cell-derived cortical neurospheres are of great interest in basic neurobiology research and drug research. Cultivation in controlled, stirred-tank bioreactors can improve the homogeneity of neural spheroid cultures and allows culture scale-up.
This video will give you an introduction on the Xuri™ W25 cell expansion system. You’ll get an overview of the system control capabilities which make it suitable for use in a regulated environment, and its flexibility to handle multiple indications with various cell types.
This video provides and overview on the Sefia™ cell processing system, The overview will show the intuitive interface with augmented process control and integrated traceability, easy to implement at your cell therapy activities.
This video provides an introduction to the Sepax™ C-Pro, cell processing system, showing how to start a procedure and preparing and installing the corresponding kit.
Watch this video to learn the important decisions that each biopharma executive must make to break down roadblocks during the critical first step of cell line development and bring their molecule to clinic successfully.
A next-generation bioprocess control station, designed as a universal platform capable of meeting the ever changing needs of all segments of the biotech and pharmaceutical sciences.
A bioreactor/fermentor control station for heat-blanketed and water-jacketed glass vessels and single-use vessels from 250 mL to 40 L.
When you select AbbVie Contract Manufacturing for your biologics product, you’re partnering with a leading developer and manufacturer that is at the forefront of biopharmaceuticals with both our own products and customers’ products. Our scientific team and state-of-the-art facilities clearly demonstrate the capability to optimize success all the way from innovation to commercialization.
With patients’ lives at the end of the pipeline, biologics contract manufacturing needs to be safe, reliable and consistent in supply. The developers of these large molecule drugs, however, are also operating in a highly competitive space. Speed-to-market is imperative, along with efficient processes and low costs. A lot of this will rest on the quality of the cell line development and the expertise of the biologics CMO you choose.
Fermentation is a critical step in both drug and toll manufacturing, as companies look to produce the core compounds that form their eventual products. While it is possible to undertake this in-house, the expertise contract fermentation services provide can improve the quality, affordability, speed and scalability of your program.