INSIGHTS ON UPSTREAM MANUFACTURING

• Expansion Of Human Bone Marrow-Derived MSCs

  Achieving over 870 million viable, quality mesenchymal stem/stromal cells is possible. This efficient cell culture method scales bone marrow-derived MSCs for clinical needs.

• Maximizing MSC Yield And Quality: A Comparative Media Study

  Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

• Comparing Advanced Cell Culture Vessels vs. Traditional Options

  Learn how innovative cell culture vessel design enables high-density cell growth with superior gas exchange and a closed system to scale up bioproduction efficiently while maintaining batch-to-batch consistency.

• Implementing A Versatile Mixing System To Drive Down Costs

  Learn how a CDMO reduced capital expenses and operational complexity by adopting an all-in-one mixing solution that supports every stage of production and a wide range of volumes.

• The Case For Optimized And Excipient GMP Cell Culture Solutions

  10/27/2025

  Learn how optimized, customizable formulations and Excipient GMP manufacturing streamline development, ensuring quality and consistency for a de-risked path to the clinic.

• A Simple And Accurate Method To Quantify Molar Concentrations

  10/24/2025

  Explore a fast, size-independent method for NGS library quantification that improves accuracy, reduces workflow time, and ensures consistent sequencing results without the need for qPCR.

• Advance Long-Term Cell Kinetics With Integrated Fluid Handling

  10/24/2025

  Examine how a novel setup enables uninterrupted long-term cell-based assays by combining CO₂ regulation and evaporation control to improve cell viability and data consistency for real-time analysis.

• Smarter CMC Strategies To Accelerate Next-Gen Biologics To The Clinic

  10/23/2025

  Learn how process design and cross-functional collaboration mitigate risks and accelerate the path from early development to FIH manufacturing through real-world case studies of practical approaches.