INSIGHTS ON UPSTREAM MANUFACTURING
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![Primrose Bio - Expression Strategy webinar]( "Improving Scale-Up Starts With Expression Strategy")
Improving Scale-Up Starts With Expression StrategyEarly expression screening and strain-engineering strategies can reveal manufacturing risks and clarify which recombinant protein candidates are worth advancing before major investments are made.
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![Why Use The GSquad® Pro Vector System]( "Why Use The GSquad® Pro Vector System?")
Why Use The GSquad® Pro Vector System?Lonza's GSPro® vector platform centers on LHP1, a high-strength promoter developed to improve titer, product quality, and expression stability across a range of recombinant protein formats.
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![How Does GS piggyBac® Transposon Technology Work]( "How Does GS piggyBac® Transposon Technology Work?")
How Does GS piggyBac® Transposon Technology Work?Targeted genomic integration offers a more deliberate path to stable, high-expressing CHO cell lines than random integration methods have traditionally allowed.
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![How Can The GS Effex® Cell Line Increase The Potency Of Therapeutic Antibodies]( "How Can The GS Effex® Cell Line Increase The Potency Of Therapeutic Antibodies?")
How Can The GS Effex® Cell Line Increase The Potency Of Therapeutic Antibodies?Learn how GS Effex® integrates into our GS Gene Expression System®, letting customers use the same expression vectors, GS piggyBac® transposase technology, and media while incorporating the cell line into existing workflows.
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What Is The GS Discovery® Transient Expression System?9/18/2026
Two transient expression approaches, one optimized for speed and one for higher titers, are examined alongside the consistency advantages of a shared host cell and vector system.
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How Do I Choose An Expression System For My Biotherapeutic Molecule?9/18/2026
Selecting an expression system early in biotherapeutic development depends on molecular complexity, glycosylation requirements, and other structural characteristics that differ across platforms.
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Bylok® Platform For IgG-like Bispecific Antibody Assembly9/18/2026
Developing IgG-like bispecific antibodies poses significant expression and product-quality challenges. Discover how the bYlok® platform is designed to address these challenges and enable more efficient bispecific development.
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Inside The Technology Advancing CHO Therapeutic Protein Expression9/18/2026
Watch as Dr. Peter O'Callaghan, Senior Director and Head of Expression System Sciences, Licensing, answers key questions about the GS Gene Expression System® and the technologies behind its performance.
UPSTREAM MANUFACTURING SOLUTIONS
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![GettyImages-2178790629 cell]( "Building A GMP-Ready Cell Line Development Strategy From Day One")
Rushing early development without planning for commercialization can lead to delays. Aligning process and analytical strategies from the start supports efficient scale-up and smoother manufacturing.
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![Adeno-Associated Virus AAV GettyImages-597972114]( "Bending The AAV Manufacturing Cost Curve: Scalable Platform Innovation And Productivity Gains")
A stable producer cell line platform designed to replace transient transfection in AAV manufacturing, offering 10 to 15-fold titer improvements and simplified workflows from development through commercial scale.
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![4605-26-01]( "Used 500 Liter Cytiva XDR-500 Bioreactor System")
Used 500 liter Cytiva XDR-500 bioreactor system, model XDR-500. Includes (2) Rosemount Analytical model 1056 dual channel intelligent transmitters and (4) peristaltic pump heads, serial# XDR-08825-001, built 2011.
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![4658-2-01]( "Used 500 Liter Sartorious Single Use Bioreactor, Model STR 500 DW")
Used 500 liter Sartorius Biostat CultiBag single use bioreactor, model STR 500 DW, stainless steel bag holder with agitator drive, jacketed for 1 bar, control system with hmi touch screen, serial# STR-0550, built 2016.
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![4605-34-01]( "Used 10 Liter GE Xcellerex XDR-10 Single-Use Stirred Tank Bioreactor (Lot of 2)")
Used lot of (2) 10 liter GE Xcellerex (Cytiva) single-use stirred tank bioreactors, model XDR-10. Includes Emerson model 1056 controllers and Mettler Toledo model PBA655-B60 20" x 16" platform scales, serial# 29188443 & 29188442, built 2016.
