INSIGHTS ON UPSTREAM MANUFACTURING
-
![GettyImages-1435391920-cell-culture-development-well-plate]( "Perfusion Cell Line Development For Intensified Processes")
Perfusion Cell Line Development For Intensified ProcessesThe biopharmaceutical industry is transforming by shifting to continuous and intensified upstream bioprocesses, which are driven by evolving demands. Discover the key goals and innovations shaping this transition for modern healthcare.
-
![GettyImages-1434627610 lab, manufacturing]( "CLD To Upstream Optimization: Enhancing Biologics Quality, Productivity")
CLD To Upstream Optimization: Enhancing Biologics Quality, ProductivityExplore how advanced cell line development and upstream processing strategies optimize both productivity and therapeutic effectiveness, ensuring the development of high-quality biologics.
-
![GettyImages-1214627273-lab-microscope-sample]( "Next-Generation Cell Therapy: Eliminating Thermal Shock In Electroporation")
Next-Generation Cell Therapy: Eliminating Thermal Shock In ElectroporationConventional electroporation methods struggle with damaging heat buildup. Discover how innovative flow technology leverages physics to protect cells and enable large-scale therapeutic production.
-
![GettyImages-513110674 lab, research, sample, vial]( "Why Cell Washing Is The Hidden Bottleneck In Gene-Edited Cell Therapy")
Why Cell Washing Is The Hidden Bottleneck In Gene-Edited Cell TherapyScaling up life-saving gene-edited cell therapies means tackling production inefficiencies. Overcoming the time-consuming and risky cell washing step is crucial for clinical and commercial success.
-
Why Cell Line Screening Is Crucial For Successful CDC Assay Development4/28/2025
In developing a CDC assay for therapeutic mAb characterization or QC release testing, in addition to selecting a target cell line that expresses the mAb ligand, consideration should be made to the expression of CRPs on the cell surface.
-
Next-Gen Biomanufacturing: Process Intensification For mAb Production4/28/2025
Intensified processes, omics-driven media, and advanced bioreactors can boost efficiency and scalability in mAb production.
-
Greater Versatility: Multi-Well Inserts Allow For A Two-Chamber System4/28/2025
Multi-well inserts allowing for a two-chamber system that can expose cell cultures from above and below can provide greater versatility and expand research options compared to many standard cell culture plates.
-
Helpful Biosafety Testing Innovations Where And When You Need Them4/24/2025
Monoclonal antibody manufacturing is advancing to boost efficiency, cut costs, and expand access, driven by innovation, demand, and the rise of biosimilars.
UPSTREAM MANUFACTURING SOLUTIONS
-
![Femtobiomed - CellShot]( "CellShot® Technology: Partitioned Flow Electroporation")
Discover an innovative electroporation technology that eliminates washing, mixing, and heating, ensuring high cell viability, efficiency, and production yield for diverse genetic applications.
-
![Corning]( "Corning® CellCube® System")
The Corning CellCube system provides a compact, perfusion-based method for the mass culture of attachment-dependent cells. CellCube modules consist of a series of 10, 25, or 100 parallel, polystyrene plates joined to create thin, sealed laminar flow spaces between adjacent plates.
-
![HSC-Kit-Box-and-Vials_100ul_0324]( "CD34+ HSC LNP Kits")
Research Use Only (RUO) lipid nanoparticle (LNP) reagents to deliver RNA into hematopoietic stem cells (HSCs) for cell and gene therapy applications.
-
![T-Cell-Kit-Ignite-Box-and-Vials-6ml]( "GenVoy-ILM™ T-Cell Kits For mRNA")
Off-the-shelf, research use only lipid nanoparticle (LNP) reagents to deliver RNA into T-cells.
-
![ACROBiosystems - cytopak]( "CytoPak Products: Closed Process Solutions For Cell Therapy")
Enhance cell therapy workflows with cutting-edge closed-system solutions that simplify processes and support consistent cell growth from research to commercial production.
