INSIGHTS ON UPSTREAM MANUFACTURING

• Single Cell Seeding Conditions For Improved Colony Outgrowth

  Cloning efficiency (colony outgrowth) is often overlooked in the cell line development workflow relative to the single cell isolation step. However, recovery and growth of the single cells is a well-known challenging step in the process.

• Testing Cell Line Development Technology Platforms In Parallel

  Access to multiple cell line development platforms — and the option to test them against one another — can minimize project risk, optimize titers, and differentiate vendor partners.

• Analyze Media Without Removing Your mAb

  Cell media analysis becomes challenging when faced with high concentrations of a protein. New mass spec-based analyzers offer a faster and simpler alternative.

• Select The Best Chemically Defined CHO Media From The Start

  A key aspect of process development is optimizing cell culture media. Whether media is sourced in-house or externally, it is vital to ensure consistency.

• Combining VIPS And ATUM To Accelerate Commercial Cell Line Manufacturing

  1/14/2022

  Scientists are constantly striving to develop the highest producing clones and to do it faster. We now demonstrate how this can be achieved by using only a handful of cloning plates.

• Cell Culture Medium Development And Analysis For Bioproduction

  1/12/2022

  Much of the increase in productivity since the start of the bioproduction era decades ago has been due to optimization of cell culture media.

• The Critical Role Of Cell Culture Media Development And Optimization

  1/12/2022

  Increased analytics capabilities have provided new insights into the relationship between cell culture media and the outcome of the final biologics product.

• At-Line Spent Media Analysis Is Now A Reality – Don’t Get Left Behind

  1/11/2022

  Spent media analysis should no longer be a lengthy process. See how an at-line analyzer removes process bottlenecks and speeds up process development.